Basic Information | |
---|---|
Species | Picea abies |
Cazyme ID | MA_10435411g0010 |
Family | GT47 |
Protein Properties | Length: 282 Molecular Weight: 31816.1 Isoelectric Point: 8.0627 |
View CDS |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 75 | 222 | 7e-35 |
FFSSDSQRELKEWKGTVASARRDFLFAFVGAERRGLGIRRAVIEQCSSSPKCVMVNCAMLKCSHRPEAVMTELLKANFCLQPSGDSPTRRSTFDALIAGC IPVFFRRDSAYEQYTWHLPSDPETYSVFIAEERMVNSRKALKIEDILS |
Full Sequence |
---|
Protein Sequence Length: 282 Download |
MAGQERKVEL EEKGRNGSFH GDRANRLGPE QAHHGEGNYL GNQSLGAPGY GECHDALGGE 60 PNVGRQRTGH SVSDFFSSDS QRELKEWKGT VASARRDFLF AFVGAERRGL GIRRAVIEQC 120 SSSPKCVMVN CAMLKCSHRP EAVMTELLKA NFCLQPSGDS PTRRSTFDAL IAGCIPVFFR 180 RDSAYEQYTW HLPSDPETYS VFIAEERMVN SRKALKIEDI LSSYSQEKIR KMREKIVEIM 240 PSLLYMNFAE KDGGEIFPKD AFDLSIEGML RKVMSSRFWN RL |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-25 | 93 | 216 | 134 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABK23792.1 | 0 | 128 | 282 | 1 | 155 | unknown [Picea sitchensis] |
RefSeq | XP_001752641.1 | 0 | 76 | 275 | 200 | 399 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001761213.1 | 0 | 76 | 273 | 230 | 427 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001763405.1 | 0 | 76 | 272 | 194 | 386 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001773063.1 | 0 | 76 | 274 | 194 | 392 | predicted protein [Physcomitrella patens subsp. patens] |
EST Download unfiltered results here | ||||
---|---|---|---|---|
Hit | Length | Start | End | EValue |
GR953898 | 219 | 64 | 282 | 0 |
GT738826 | 220 | 63 | 282 | 0 |
ES870503 | 196 | 87 | 282 | 0 |
DR571231 | 182 | 101 | 282 | 0 |
GT241877 | 207 | 76 | 282 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
---|