Basic Information | |
---|---|
Species | Picea abies |
Cazyme ID | MA_125709g0010 |
Family | GT47 |
Protein Properties | Length: 528 Molecular Weight: 60666.5 Isoelectric Point: 8.6016 |
View CDS |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 193 | 479 | 0 |
KILNVYVYPDGEKPYFHEGPMGAIYASEGWFMKQMEDNKQFVTKDFRKAHVYYMPYSVYEMRRGIPAPEQHNMPQISLYIRDYVNTIASKYPFWNRTHGR DHFFVACHDWGPYTTKEHPELRLNAIKVLCNADLSEGYFVSGKDGALPETNLDCLQQPPRGLGGLPVRKRSILAFFAGGNHGRVRPVLFKYWKDKDPGIK VYENLPQEIAKEKSYINHMKESKYCLCPMGYEVSSPRLVEAIYYDCVPVIIADHFFLPFSEVLNWESFSITVAEKDIPKLKTILLGI |
Full Sequence |
---|
Protein Sequence Length: 528 Download |
MERAGIVGSK IWKEELKKLV VILAGATAIY ALVQAWRTGY STGIRFSFDR FNGPGTGNYT 60 SNPPPAAISL QSRYGGVEHE YHSINNLSLR GTDALAPAGS FEIEKKNQSM IGSASTNDSL 120 DAHDLKLNDS VTNGANSTIL TTKEEWVITI EQQLLSAKCE IENAVPVLDN PELYGPVYYN 180 VSRFKRSYEM MEKILNVYVY PDGEKPYFHE GPMGAIYASE GWFMKQMEDN KQFVTKDFRK 240 AHVYYMPYSV YEMRRGIPAP EQHNMPQISL YIRDYVNTIA SKYPFWNRTH GRDHFFVACH 300 DWGPYTTKEH PELRLNAIKV LCNADLSEGY FVSGKDGALP ETNLDCLQQP PRGLGGLPVR 360 KRSILAFFAG GNHGRVRPVL FKYWKDKDPG IKVYENLPQE IAKEKSYINH MKESKYCLCP 420 MGYEVSSPRL VEAIYYDCVP VIIADHFFLP FSEVLNWESF SITVAEKDIP KLKTILLGIS 480 ERRYMSMHFR LSKVRKHFLW HRKSPQRYDI FHMILHSVWK SRLHEINC |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-59 | 191 | 479 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI23466.1 | 0 | 146 | 527 | 154 | 534 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_567512.2 | 0 | 124 | 525 | 129 | 530 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002269459.1 | 0 | 146 | 527 | 154 | 534 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002457517.1 | 0 | 146 | 526 | 141 | 520 | hypothetical protein SORBIDRAFT_03g008610 [Sorghum bicolor] |
RefSeq | XP_002530666.1 | 0 | 146 | 527 | 143 | 524 | catalytic, putative [Ricinus communis] |