| Basic Information | |
|---|---|
| Species | Picea abies |
| Cazyme ID | MA_159099g0140 |
| Family | GT28 |
| Protein Properties | Length: 359 Molecular Weight: 37394.7 Isoelectric Point: 11.0705 |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT28 | 183 | 344 | 4.2039e-45 |
| LLVVGGSQGARIMADIVPPAIERLEPALWRRLSLVQQVREEDMSRVRAVYDRLKIEAELAPFFADLPARLAATHLVVSRSGAGTVAELGAIGRPSILVPL PGAIDQDQFANAGVLEKVGGAIRIPQNEFTPDRLASEISALAADPARLTTTATSARSVGRLD | |||
| Full Sequence |
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| Protein Sequence Length: 359 Download |
| MLAAGGTGGH LFPAEALGVA LMKRGARVRL MTDSRAVRYG GMFTSDMMDV VPSETVRGRT 60 PWALARTGAM LAAGGAMSLA LLLRQKPKAV IGFGGYPTLP PLIAAKLLGI PTIIHDSNAV 120 LGRANRLLST RVSAIATSLP GVLDRDPALA GKATVTGTPM RPAILAAAAV PYASPDTRGP 180 LRLLVVGGSQ GARIMADIVP PAIERLEPAL WRRLSLVQQV REEDMSRVRA VYDRLKIEAE 240 LAPFFADLPA RLAATHLVVS RSGAGTVAEL GAIGRPSILV PLPGAIDQDQ FANAGVLEKV 300 GGAIRIPQNE FTPDRLASEI SALAADPARL TTTATSARSV GRLDAAERLA DLAVKVAGI 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam04101 | Glyco_tran_28_C | 1.0e-26 | 182 | 327 | 146 | + Glycosyltransferase family 28 C-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site. | ||
| TIGR01133 | murG | 7.0e-69 | 1 | 327 | 333 | + undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]. | ||
| COG0707 | MurG | 1.0e-73 | 1 | 327 | 329 | + UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell envelope biogenesis, outer membrane] | ||
| cd03785 | GT1_MurG | 9.0e-102 | 1 | 327 | 328 | + MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. | ||
| PRK00726 | murG | 5.0e-107 | 1 | 327 | 333 | + undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | YP_001242004.1 | 0 | 1 | 359 | 9 | 367 | undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase [Bradyrhizobium sp. BTAi1] |
| RefSeq | YP_002288240.1 | 0 | 1 | 359 | 1 | 359 | undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase [Oligotropha carboxidovorans OM5] |
| RefSeq | YP_485613.1 | 0 | 1 | 359 | 8 | 366 | undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase [Rhodopseudomonas palustris HaA2] |
| RefSeq | YP_570519.1 | 0 | 1 | 359 | 8 | 366 | undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase [Rhodopseudomonas palustris BisB5] |
| RefSeq | YP_781031.1 | 0 | 1 | 359 | 8 | 366 | undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase [Rhodopseudomonas palustris BisA53] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3s2u_A | 1.00053e-42 | 1 | 357 | 6 | 355 | A Chain A, Crystal Structure Of The Pseudomonas Aeruginosa Murg:udp-glcnac Substrate Comp |
| PDB | 1nlm_B | 1e-39 | 1 | 357 | 10 | 354 | A Chain A, Crystal Structure Of The Pseudomonas Aeruginosa Murg:udp-glcnac Substrate Comp |
| PDB | 1nlm_A | 1e-39 | 1 | 357 | 10 | 354 | A Chain A, Crystal Structure Of The Pseudomonas Aeruginosa Murg:udp-glcnac Substrate Comp |
| PDB | 1f0k_B | 1e-39 | 1 | 357 | 10 | 354 | A Chain A, The 1.9 Angstrom Crystal Structure Of E. Coli Murg |
| PDB | 1f0k_A | 1e-39 | 1 | 357 | 10 | 354 | A Chain A, The 1.9 Angstrom Crystal Structure Of E. Coli Murg |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| ES821435 | 333 | 2 | 310 | 0.000000000000002 |
| CO115843 | 254 | 86 | 326 | 0.000000000000004 |
| CN815584 | 145 | 183 | 327 | 0.0000000000004 |
| DT604869 | 146 | 178 | 321 | 0.000000000001 |
| FL480091 | 86 | 241 | 326 | 0.0000000001 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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