Basic Information | |
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Species | Picea abies |
Cazyme ID | MA_159144g0050 |
Family | AA3 |
Protein Properties | Length: 545 Molecular Weight: 59340.6 Isoelectric Point: 9.4519 |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 6 | 535 | 0 |
YDYIIVGAGSAGCVLASRLSEDPNVNVLLIEAGAPSASIFVHMPAGIRVLYTSPKYNWQFWTEPQAHLNNRKIYIPRGRVVGGSSSINSMIAIRGNAWDY DSWADQGLPSWSYENLRPYLRKIEDATLVTRERNQDRGYSGPIRLSYGTLQHPISKAFIESAVSTGMRENNGFNGPSQIGAGFYELTIAEGKRSGAFKYL DRAKGRSNLTLMANCRVRRIAMEGTRARGVVIEKGGREIKISAEREVLLTSGAIGSPQLLMLSGIGPADHLHSLGIKPVLDSAGVGDNLQDHLDCAIRLE ASQPVTLTPYLGLIKGGLAGAQYILRGTGPATSQGVEAGAFWGPDKNSSLPEWQAHLIVALRNPPPNERIDHGFAIRVCQLRPKSRGTLRLRSADPSDTP AIDPRFLSDESDFVSMQEGVKQLCEIIDQPGLRKFVKRKIDIDAFTSVTSRKEWIRARAETIYHPVGTCRMGVDSNAVVDGQLRVRGIDNLRVIDGSIMP TVISGNTNLPIMAMAEKAAELVEGSNETRH |
Full Sequence |
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Protein Sequence Length: 545 Download |
MKLSGYDYII VGAGSAGCVL ASRLSEDPNV NVLLIEAGAP SASIFVHMPA GIRVLYTSPK 60 YNWQFWTEPQ AHLNNRKIYI PRGRVVGGSS SINSMIAIRG NAWDYDSWAD QGLPSWSYEN 120 LRPYLRKIED ATLVTRERNQ DRGYSGPIRL SYGTLQHPIS KAFIESAVST GMRENNGFNG 180 PSQIGAGFYE LTIAEGKRSG AFKYLDRAKG RSNLTLMANC RVRRIAMEGT RARGVVIEKG 240 GREIKISAER EVLLTSGAIG SPQLLMLSGI GPADHLHSLG IKPVLDSAGV GDNLQDHLDC 300 AIRLEASQPV TLTPYLGLIK GGLAGAQYIL RGTGPATSQG VEAGAFWGPD KNSSLPEWQA 360 HLIVALRNPP PNERIDHGFA IRVCQLRPKS RGTLRLRSAD PSDTPAIDPR FLSDESDFVS 420 MQEGVKQLCE IIDQPGLRKF VKRKIDIDAF TSVTSRKEWI RARAETIYHP VGTCRMGVDS 480 NAVVDGQLRV RGIDNLRVID GSIMPTVISG NTNLPIMAMA EKAAELVEGS NETRHSGAAP 540 KKQTA |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam05199 | GMC_oxred_C | 8.0e-46 | 388 | 523 | 140 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
TIGR03970 | Rv0697 | 3.0e-82 | 7 | 527 | 536 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
TIGR01810 | betA | 1.0e-149 | 7 | 529 | 531 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
COG2303 | BetA | 8.0e-157 | 6 | 527 | 533 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
PRK02106 | PRK02106 | 0 | 1 | 529 | 547 | + choline dehydrogenase; Validated |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABC96764.1 | 0 | 3 | 531 | 1 | 528 | polyethylene glycol dehydrogenase [Ensifer sp. as08] |
GenBank | ACF98205.1 | 0 | 6 | 545 | 7 | 550 | putative choline dehydrogenase precursor [uncultured bacterium 1114] |
RefSeq | NP_102692.1 | 0 | 6 | 538 | 2 | 532 | dehydrogenase [Mesorhizobium loti MAFF303099] |
RefSeq | ZP_06122900.1 | 0 | 6 | 529 | 6 | 534 | glucose-methanol-choline oxidoreductase [Caulobacter segnis ATCC 21756] |
RefSeq | ZP_06356986.1 | 0 | 1 | 529 | 1 | 529 | glucose-methanol-choline oxidoreductase [Rhodopseudomonas palustris DX-1] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3t37_A | 0 | 7 | 524 | 19 | 517 | A Chain A, Crystal Structure Of Pyridoxine 4-Oxidase From Mesorbium Loti |
PDB | 3fim_B | 0 | 6 | 529 | 3 | 564 | B Chain B, Crystal Structure Of Aryl-Alcohol-Oxidase From Pleurotus Eryingii |
PDB | 2jbv_B | 0 | 6 | 527 | 14 | 526 | A Chain A, Crystal Structure Of Choline Oxidase Reveals Insights Into The Catalytic Mechanism |
PDB | 2jbv_A | 0 | 6 | 527 | 14 | 526 | A Chain A, Crystal Structure Of Choline Oxidase Reveals Insights Into The Catalytic Mechanism |
PDB | 3nne_H | 0 | 6 | 527 | 14 | 526 | A Chain A, Crystal Structure Of Choline Oxidase S101a Mutant |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO408029 | 425 | 119 | 507 | 0 |
GW450763 | 176 | 6 | 181 | 1.4013e-45 |
FG012833 | 206 | 6 | 205 | 4.2039e-45 |
EG737069 | 243 | 68 | 303 | 1.99965e-42 |
GW453775 | 254 | 255 | 499 | 1.99993e-41 |
Sequence Alignments (This image is cropped. Click for full image.) |
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