| Basic Information | |
|---|---|
| Species | Picea abies |
| Cazyme ID | MA_159153g0080 |
| Family | AA3 |
| Protein Properties | Length: 578 Molecular Weight: 62205.8 Isoelectric Point: 8.6847 |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| AA3 | 54 | 574 | 0 |
| RAYAASSKDIESIDGGYDYIVIGSGSSGGTLAYRLATKTDARILVLEAGSVDDIPELHDPRLWAAALATKATKSFDTVAQPHTAGRTHSWPRGNVLGGTS CLNAMIFARGHRSDYDGWAAAGCTGWDYASVLKHFKELETFEGGASDLRGASGPLYISQPKKDKAHPGAAAFIEAAVDLGYPETKDFNGPTMEGPAWVNF NIKDQQRQSTAVAFLKPAMERKNLTVLTDAPVTQLVFEGTRCVGVEYLHNGKPRTIRAEREVIVSAGAVDTPRILMLSGIGNASDLGKLGIKSIVDLKGV GENLQDHVLGAGPNYESPTPLPASNYNHSEVYMWWKSEAKLAAPDMITLYVSIPFSTPALPMKDVKNGWCMLSGVARPTSRGRLKLASAKYGDAPIIDPN YLATEHDRKVFSKATEIAREIALHKAYGSQRSREVLPGKDIKVGSPEWNEFLAKSVNTYFHPTSTCRMGADEMAVVDPQLKVRGVSGLRIADASIMPSIT TSNTNAPSIMIGWKCAEMISA | |||
| Full Sequence |
|---|
| Protein Sequence Length: 578 Download |
| MTSTKDRGHH LPIDESIRRL SLGQMSRRVF VGNAVAAGLT LGMAGSLASI YSSRAYAASS 60 KDIESIDGGY DYIVIGSGSS GGTLAYRLAT KTDARILVLE AGSVDDIPEL HDPRLWAAAL 120 ATKATKSFDT VAQPHTAGRT HSWPRGNVLG GTSCLNAMIF ARGHRSDYDG WAAAGCTGWD 180 YASVLKHFKE LETFEGGASD LRGASGPLYI SQPKKDKAHP GAAAFIEAAV DLGYPETKDF 240 NGPTMEGPAW VNFNIKDQQR QSTAVAFLKP AMERKNLTVL TDAPVTQLVF EGTRCVGVEY 300 LHNGKPRTIR AEREVIVSAG AVDTPRILML SGIGNASDLG KLGIKSIVDL KGVGENLQDH 360 VLGAGPNYES PTPLPASNYN HSEVYMWWKS EAKLAAPDMI TLYVSIPFST PALPMKDVKN 420 GWCMLSGVAR PTSRGRLKLA SAKYGDAPII DPNYLATEHD RKVFSKATEI AREIALHKAY 480 GSQRSREVLP GKDIKVGSPE WNEFLAKSVN TYFHPTSTCR MGADEMAVVD PQLKVRGVSG 540 LRIADASIMP SITTSNTNAP SIMIGWKCAE MISATSRT |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
 | ||||||||
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam00732 | GMC_oxred_N | 1.0e-44 | 138 | 360 | 231 | + GMC oxidoreductase. This family of proteins bind FAD as a cofactor. | ||
| TIGR03970 | Rv0697 | 4.0e-82 | 71 | 573 | 515 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
| TIGR01810 | betA | 9.0e-120 | 71 | 572 | 536 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| COG2303 | BetA | 3.0e-132 | 70 | 577 | 539 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| PRK02106 | PRK02106 | 3.0e-165 | 70 | 572 | 541 | + choline dehydrogenase; Validated | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | YP_001532771.1 | 0 | 25 | 573 | 1 | 541 | glucose-methanol-choline oxidoreductase [Dinoroseobacter shibae DFL 12] |
| RefSeq | YP_001865616.1 | 0 | 70 | 577 | 4 | 507 | glucose-methanol-choline oxidoreductase [Nostoc punctiforme PCC 73102] |
| RefSeq | YP_001923964.1 | 0 | 12 | 572 | 9 | 567 | glucose-methanol-choline oxidoreductase [Methylobacterium populi BJ001] |
| RefSeq | ZP_01890564.1 | 0 | 70 | 572 | 3 | 498 | Glucose-methanol-choline oxidoreductase [unidentified eubacterium SCB49] |
| RefSeq | ZP_05513194.1 | 0 | 70 | 572 | 10 | 506 | glucose-methanol-choline oxidoreductase [Streptomyces hygroscopicus ATCC 53653] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3t37_A | 0 | 71 | 564 | 19 | 512 | A Chain A, Crystal Structure Of Pyridoxine 4-Oxidase From Mesorbium Loti |
| PDB | 3nne_H | 0 | 62 | 574 | 5 | 528 | A Chain A, Crystal Structure Of Choline Oxidase S101a Mutant |
| PDB | 3nne_G | 0 | 62 | 574 | 5 | 528 | A Chain A, Crystal Structure Of Choline Oxidase S101a Mutant |
| PDB | 3nne_F | 0 | 62 | 574 | 5 | 528 | A Chain A, Crystal Structure Of Choline Oxidase S101a Mutant |
| PDB | 3nne_E | 0 | 62 | 574 | 5 | 528 | A Chain A, Crystal Structure Of Choline Oxidase S101a Mutant |
