Basic Information | |
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Species | Picea abies |
Cazyme ID | MA_165077g0010 |
Family | GH116 |
Protein Properties | Length: 337 Molecular Weight: 35821.6 Isoelectric Point: 4.3382 |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GH116 | 94 | 211 | 7.4e-31 |
TEVILDAFLKTTIAKGEKSFAHAVWPSVYMAMAYMDQFYQDKDGMIENEGFPDQIYDAWSVSGVSAYSGGLWVAALQAAAVMADESASAVDVGSSHVAES TPQRLANTSQHIPARLFN |
Full Sequence |
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Protein Sequence Length: 337 Download |
MSPLEILASS AIRTANKAKA TLIVVLTHGG TTTKLVAKYR PTIPILSIVV PILTTDSFDW 60 TCSDETPARH SLIYRGLIPL LAEGSTKATD SESTEVILDA FLKTTIAKGE KSFAHAVWPS 120 VYMAMAYMDQ FYQDKDGMIE NEGFPDQIYD AWSVSGVSAY SGGLWVAALQ AAAVMADESA 180 SAVDVGSSHV AESTPQRLAN TSQHIPARLF NTPPAIDPSH TQTGSTPIAG DHEHDIPLQP 240 EVAEPHAGAG GSGSGSDDTG SNNITEPITS TTEQFVDSRE QPQDGASVQP HESEVQPPDS 300 EVQPPESEVK PNPNITGSVQ PHDVALHESH DGNMVVY |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam02887 | PK_C | 4.0e-14 | 5 | 90 | 86 | + Pyruvate kinase, alpha/beta domain. As well as being found in pyruvate kinase this family is found as an isolated domain in some bacterial proteins. | ||
pfam04685 | DUF608 | 7.0e-21 | 109 | 166 | 58 | + Protein of unknown function, DUF608. This family represents a conserved region with a pankaryotic distribution in a number of uncharacterized proteins. | ||
cd00288 | Pyruvate_Kinase | 2.0e-21 | 1 | 109 | 109 | + Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer. | ||
PLN02765 | PLN02765 | 1.0e-27 | 1 | 112 | 112 | + pyruvate kinase | ||
PLN02461 | PLN02461 | 1.0e-56 | 1 | 109 | 109 | + Probable pyruvate kinase |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAY86035.1 | 0 | 1 | 117 | 376 | 492 | pyruvate kinase [Citrus sinensis] |
GenBank | ABR16411.1 | 0 | 1 | 109 | 376 | 484 | unknown [Picea sitchensis] |
GenBank | ABR18162.1 | 0 | 1 | 109 | 376 | 484 | unknown [Picea sitchensis] |
RefSeq | XP_002315362.1 | 0 | 1 | 109 | 378 | 486 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002513157.1 | 0 | 1 | 117 | 374 | 490 | pyruvate kinase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3pp7_B | 0.00001 | 1 | 61 | 374 | 434 | A Chain A, Crystal Structure Of Leishmania Mexicana Pyruvate Kinase In Complex With The Drug Suramin, An Inhibitor Of Glycolysis. |
PDB | 3pp7_A | 0.00001 | 1 | 61 | 374 | 434 | A Chain A, Crystal Structure Of Leishmania Mexicana Pyruvate Kinase In Complex With The Drug Suramin, An Inhibitor Of Glycolysis. |
PDB | 3srk_B | 0.00001 | 1 | 61 | 375 | 435 | A Chain A, Crystal Structure Of Leishmania Mexicana Pyruvate Kinase In Complex With The Drug Suramin, An Inhibitor Of Glycolysis. |
PDB | 3srk_A | 0.00001 | 1 | 61 | 375 | 435 | A Chain A, Crystal Structure Of Leishmania Mexicana Pyruvate Kinase In Complex With The Drug Suramin, An Inhibitor Of Glycolysis. |
PDB | 3qv8_A | 0.00001 | 1 | 61 | 375 | 435 | A Chain A, Crystal Structure Of Leishmania Mexicana Pyruvate Kinase In Complex With The Drug Suramin, An Inhibitor Of Glycolysis. |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
AM169200 | 109 | 1 | 109 | 0 |
AM168852 | 109 | 1 | 109 | 0 |
DR099020 | 109 | 1 | 109 | 0 |
ES671035 | 109 | 1 | 109 | 0 |
CO489490 | 109 | 1 | 109 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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