| Basic Information | |
|---|---|
| Species | Picea abies |
| Cazyme ID | MA_18829g0010 |
| Family | GT47 |
| Protein Properties | Length: 420 Molecular Weight: 48020.6 Isoelectric Point: 8.2629 |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 53 | 348 | 0 |
| RLKVFIYELPSKYNKKILAKDPRCLTHMFATEIFMNRFLLGSPVRTLNPEEADWFYTPVYTTCDLTPNGLPLPFKSPRMMRSAIQYISTNWPYWNRTEGA DHFFVVPHDFGACFHYQEEKAIERGILPLLQRATLVQTFGQRYHVCLKKGSITVPPYAPPQKMQAHLIPPSTPRSIFVYFRGLFYDVGNDPEGGYYARGA RASVWENFKDNPLFDISTEHPATYYEDMQRAIFCLCPLGWAPWSPRLVEGVIFGCIPVIIADDIVLPFADAIPWEEIGVFVAEKDVPNLDTILTSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 420 Download |
| MRRKRELPQR SFFVLFLFLL IVPAFGQKQQ EHQRSERIAG SAGDVLEDDP VGRLKVFIYE 60 LPSKYNKKIL AKDPRCLTHM FATEIFMNRF LLGSPVRTLN PEEADWFYTP VYTTCDLTPN 120 GLPLPFKSPR MMRSAIQYIS TNWPYWNRTE GADHFFVVPH DFGACFHYQE EKAIERGILP 180 LLQRATLVQT FGQRYHVCLK KGSITVPPYA PPQKMQAHLI PPSTPRSIFV YFRGLFYDVG 240 NDPEGGYYAR GARASVWENF KDNPLFDIST EHPATYYEDM QRAIFCLCPL GWAPWSPRLV 300 EGVIFGCIPV IIADDIVLPF ADAIPWEEIG VFVAEKDVPN LDTILTSIPP EVILRKQRLL 360 ANPAMKQAML FPQPAQPGDA FHQILNGLAR KLPHDSSIYL KPNQKILNWT AGPPGDLKPW 420 |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| pfam03016 | Exostosin | 1.0e-81 | 53 | 348 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABK26875.1 | 0 | 1 | 420 | 1 | 420 | unknown [Picea sitchensis] |
| RefSeq | NP_568941.1 | 0 | 33 | 420 | 28 | 415 | GUT1; catalytic/ glucuronoxylan glucuronosyltransferase [Arabidopsis thaliana] |
| RefSeq | XP_002284685.1 | 0 | 6 | 420 | 2 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002318180.1 | 0 | 33 | 420 | 30 | 417 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002511079.1 | 0 | 14 | 420 | 11 | 417 | catalytic, putative [Ricinus communis] |
