| Basic Information | |
|---|---|
| Species | Picea abies |
| Cazyme ID | MA_46380g0010 |
| Family | AA3 |
| Protein Properties | Length: 561 Molecular Weight: 61443.9 Isoelectric Point: 8.2405 |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| AA3 | 52 | 545 | 0 |
| TLMSEVEEYDYIVVGGGTAGCPLASTLSQNFRVLLLERGGLGYTMPTVVQEEGFYVNLLSADDDASPAQSFTSEEGVVNSRGRVLGGSSSINAGFYTRAG SAYIRGAGWDEALVNESYRWVEDTVVFRPALRQWQSAFRNGLYEAGVRPYNGYSLEHVAGTKIGGSTFDSDGRRHSSADLLQHANFSNLRIVLHAMVSRI LFTNAAPEGDRSRPKSTGVEYMDAYGIAHRAVLNPARGGEVIISSGAIGSPQLLLLSGIGPREHLASLRIPVVLDLPAVGQGMADNPRNGITVISPLPLE YSLIQVVGILPESFIEASSAPIYNRFYESGRPIENDPDQASSMRNGERPNSFGRYVYMGSIIEKVAAPLSKGELRLRSVDVRANPSVRFNYFSNRVDLQN CVRGLRTINRVLKTRSIKPYITRFIGPQLPANTSDNEAMEAFCRQTVTTLWHYHGGCQVGTVVNEKYQVLGIDSLRVIDGSTFNMSPGTNPQGS | |||
| Full Sequence |
|---|
| Protein Sequence Length: 561 Download |
| MKRTLAFTML RKMLYTPAMI FLFVCLIANI QFITVAAAAR NPSYMSVCYN ATLMSEVEEY 60 DYIVVGGGTA GCPLASTLSQ NFRVLLLERG GLGYTMPTVV QEEGFYVNLL SADDDASPAQ 120 SFTSEEGVVN SRGRVLGGSS SINAGFYTRA GSAYIRGAGW DEALVNESYR WVEDTVVFRP 180 ALRQWQSAFR NGLYEAGVRP YNGYSLEHVA GTKIGGSTFD SDGRRHSSAD LLQHANFSNL 240 RIVLHAMVSR ILFTNAAPEG DRSRPKSTGV EYMDAYGIAH RAVLNPARGG EVIISSGAIG 300 SPQLLLLSGI GPREHLASLR IPVVLDLPAV GQGMADNPRN GITVISPLPL EYSLIQVVGI 360 LPESFIEASS APIYNRFYES GRPIENDPDQ ASSMRNGERP NSFGRYVYMG SIIEKVAAPL 420 SKGELRLRSV DVRANPSVRF NYFSNRVDLQ NCVRGLRTIN RVLKTRSIKP YITRFIGPQL 480 PANTSDNEAM EAFCRQTVTT LWHYHGGCQV GTVVNEKYQV LGIDSLRVID GSTFNMSPGT 540 NPQGSTDRPS ICLLELIPKL Q |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
 | ||||||||
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| TIGR03970 | Rv0697 | 8.0e-34 | 61 | 545 | 526 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
| TIGR01810 | betA | 2.0e-45 | 61 | 534 | 535 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| COG2303 | BetA | 8.0e-55 | 58 | 548 | 539 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| PRK02106 | PRK02106 | 1.0e-58 | 58 | 555 | 585 | + choline dehydrogenase; Validated | ||
| PLN02785 | PLN02785 | 0 | 43 | 545 | 538 | + Protein HOTHEAD | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABE65766.1 | 0 | 40 | 545 | 34 | 534 | mandelonitrile lyase [Arabidopsis thaliana] |
| RefSeq | NP_177448.1 | 0 | 40 | 545 | 34 | 534 | (R)-mandelonitrile lyase, putative / (R)-oxynitrilase, putative [Arabidopsis thaliana] |
| RefSeq | XP_002277531.1 | 0 | 9 | 545 | 1 | 530 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002311915.1 | 0 | 41 | 545 | 1 | 501 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002454481.1 | 0 | 18 | 545 | 10 | 563 | hypothetical protein SORBIDRAFT_04g031910 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1ju2_B | 0 | 43 | 544 | 10 | 500 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 1ju2_A | 0 | 43 | 544 | 10 | 500 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdp_B | 0 | 43 | 544 | 10 | 500 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdp_A | 0 | 43 | 544 | 10 | 500 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdn_B | 0 | 43 | 544 | 10 | 500 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
