| Basic Information | |
|---|---|
| Species | Picea abies |
| Cazyme ID | MA_9984677g0010 |
| Family | GT47 |
| Protein Properties | Length: 411 Molecular Weight: 47410.3 Isoelectric Point: 8.0162 |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GT47 | 78 | 360 | 0 |
| NFKIFIYPRKHHDFGSPEWCSNRTFRDLDKPVTLFYESLVNSAFTTDDPEEAHLFFMPFSIDALRITSVTRTSRFLRRYIDGLRAEYPYWNRTLGADHFY VSCEGIDIDSSRNVVELKKNAIQVSCYPLPVSGNLRFYPHKDINMPPIDSAAPGHKILNFEPNRRQSQTILAYCVSWPEAFPDLESTLSLWKTDPGFLLD PLVVEPSLYARRLSSSRFCLNFIGGGGNPLFLIDAMTFGCIPVIISSSPFFDLPFQDVLNWKEFLVIVNTRQVSKLKQLLQSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 411 Download |
| MAWRIFAAIL ISVLPLCIHH PKQACGIDNQ GSTIPNTLYE NTDINANERT PLSTYAVHNT 60 LYLSASIFEA NYEQMLPNFK IFIYPRKHHD FGSPEWCSNR TFRDLDKPVT LFYESLVNSA 120 FTTDDPEEAH LFFMPFSIDA LRITSVTRTS RFLRRYIDGL RAEYPYWNRT LGADHFYVSC 180 EGIDIDSSRN VVELKKNAIQ VSCYPLPVSG NLRFYPHKDI NMPPIDSAAP GHKILNFEPN 240 RRQSQTILAY CVSWPEAFPD LESTLSLWKT DPGFLLDPLV VEPSLYARRL SSSRFCLNFI 300 GGGGNPLFLI DAMTFGCIPV IISSSPFFDL PFQDVLNWKE FLVIVNTRQV SKLKQLLQSI 360 PEARSQKMKN LAKEASRHLK WHSTPRPYDA FYSIMYQLWL RRHTIRYAQE L 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-35 | 75 | 360 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001753053.1 | 0 | 44 | 411 | 94 | 463 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_002282317.1 | 0 | 62 | 410 | 32 | 357 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002311191.1 | 0 | 59 | 407 | 24 | 339 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002316258.1 | 0 | 60 | 409 | 25 | 335 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002524235.1 | 0 | 66 | 409 | 33 | 333 | conserved hypothetical protein [Ricinus communis] |
