Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000086882 |
Family | GT47 |
Protein Properties | Length: 794 Molecular Weight: 90258.7 Isoelectric Point: 6.4969 |
Chromosome | Chromosome/Scaffold: 019413437 Start: 1788 End: 6665 |
Description | exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 349 | 702 | 0 |
KKRPLIYVYDLPPDFNSLLLEGRHFRLECVNRIYDDRNSTLWTDQLYGAQMALYESILASPYRTLNGEEADFFFVPVLDSCIITRAXDAPHLSXQEHKGL RSSLTLEYYRKAYDHIVEQYPFWNRSSGRDHIWFFSWDEGACYAPKEIWSSMMLVHWGNTNSKHKHSTTAYWADNWNDISSDKRGNHPCFDPDKDLVLPA WKSPDVNSLSSKLWSRSRENRKTLFYFNGNLGPAYPNGRPEASYSMGIRQKLAEEFGSSPNKEGKLGKQHAEDVIVTPLRXENYHLDIASSIFCGVFPGD GWSGRMEDCVLQGCIPVVIQDGIFLPYENVLNYESFAVRXREDEIPNLINILRA |
Full Sequence |
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Protein Sequence Length: 794 Download |
LXIQKWKCPX SQIATVTSVV ALVSIVLVPI VHLFWFPLVP SFAYFSQAQN SCVPINGSAD 60 SIXDHVKGNX KSPMDLDRQF PSDLHKAVVF RGAPWKAEIG RWLAGCHSIS NEVDIVEIIG 120 GSRCKNDCSG QGVCNHELGE CRCFHGYSGE GCSERQQLEC NYPATPDLPY GRWVVSICSA 180 HCDTTKAMCF CGEXTKYPNR PMAESCGFQV KLPSEPGAPK LTAWAEADLD NVFTTNSSKP 240 GWCNVDPAEA YALKVKFKEE CDCKYDGFGG RFCEVPTVCT CINQCSGRGH CRGGFCQCNN 300 GWYGIDCSIP SVASSVREWP QWLRPAQVDV PDSSHLPGKV DNLNAVVKKK RPLIYVYDLP 360 PDFNSLLLEG RHFRLECVNR IYDDRNSTLW TDQLYGAQMA LYESILASPY RTLNGEEADF 420 FFVPVLDSCI ITRAXDAPHL SXQEHKGLRS SLTLEYYRKA YDHIVEQYPF WNRSSGRDHI 480 WFFSWDEGAC YAPKEIWSSM MLVHWGNTNS KHKHSTTAYW ADNWNDISSD KRGNHPCFDP 540 DKDLVLPAWK SPDVNSLSSK LWSRSRENRK TLFYFNGNLG PAYPNGRPEA SYSMGIRQKL 600 AEEFGSSPNK EGKLGKQHAE DVIVTPLRXE NYHLDIASSI FCGVFPGDGW SGRMEDCVLQ 660 GCIPVVIQDG IFLPYENVLN YESFAVRXRE DEIPNLINIL RAFNETEIKF RLANVQKIWQ 720 RFLYRDSIML EAERQKTVFG RMREWAAQFS QLIEDDVXAT LIQVLHYKLH NDPWRQHVHV 780 KREFGLPQEC LFES |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam07974 | EGF_2 | 0.0008 | 279 | 307 | 31 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
pfam03016 | Exostosin | 2.0e-63 | 348 | 703 | 360 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN80640.1 | 0 | 3 | 785 | 5 | 809 | hypothetical protein [Vitis vinifera] |
EMBL | CBI29877.1 | 0 | 3 | 794 | 33 | 821 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002277596.1 | 0 | 3 | 794 | 5 | 793 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002308967.1 | 0 | 41 | 794 | 37 | 792 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002526728.1 | 0 | 76 | 791 | 23 | 725 | catalytic, putative [Ricinus communis] |