Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000126193 |
Family | GT21 |
Protein Properties | Length: 569 Molecular Weight: 64203.5 Isoelectric Point: 7.861 |
Chromosome | Chromosome/Scaffold: 011327222 Start: 213 End: 4659 |
Description | Nucleotide-diphospho-sugar transferases superfamily protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT21 | 105 | 289 | 1.2e-30 |
PRVTVVMPLKGFGEHNLHNWRTQVTSLYGGHLEFMFIVESTEDPAYXAVSMLLSELKDEVDAKIVVAGISTTCSQKIHNQLIGVEKMHKASKYVLFLDDD VRLHPGSIGALTTEMEKNPDIFIQTGYPLDLPSGSLGSYCIYEYHMPCSMGFATGGRTFFLWGGCMMMHADDFRLNRYGVVTGLK |
Full Sequence |
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Protein Sequence Length: 569 Download |
MSALDPLDSL LFSLSRAFCS PLAVFVQIQL YNGGQIYDFW VREVKNPENE GCLICLLLAF 60 GWACAAYVRN REINRMKDSM QRGNSFAFLC HDITELEHSN QLKLPRVTVV MPLKGFGEHN 120 LHNWRTQVTS LYGGHLEFMF IVESTEDPAY XAVSMLLSEL KDEVDAKIVV AGISTTCSQK 180 IHNQLIGVEK MHKASKYVLF LDDDVRLHPG SIGALTTEME KNPDIFIQTG YPLDLPSGSL 240 GSYCIYEYHM PCSMGFATGG RTFFLWGGCM MMHADDFRLN RYGVVTGLKN GGYSDDMTLA 300 AIAGAHKRLI TSPPVAVFPH PLASDLTFPR YWNYLRKQTF VLESYTTTVN WIMNRALFTV 360 HCYLSWGFVT PFLMAIIHIT AALRMYITGY SIEETTFTFG GLKLVGCLAT CTXIELLSMW 420 NLTRIEVHLC NMLSPEAPKL SLATYNWSLK NQSFVISISL KIQTSYLVGA LERLDDGYXV 480 FIALIVDNFL YPISAFRSHF SQSINWSGIR YHLKDGKIFK IERSKDMGPI YTDLGGKHLG 540 KKGAPPKLSF LSSLARSLAQ WXQPKKYDI |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam13632 | Glyco_trans_2_3 | 0.0003 | 197 | 387 | 202 | + Glycosyl transferase family group 2. Members of this family of prokaryotic proteins include putative glucosyltransferases, which are involved in bacterial capsule biosynthesis. | ||
cd04186 | GT_2_like_c | 7.0e-5 | 182 | 278 | 97 | + Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families. | ||
COG1215 | COG1215 | 8.0e-7 | 100 | 389 | 306 | + Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane] | ||
cd02520 | Glucosylceramide_synthase | 8.0e-8 | 105 | 225 | 124 | + Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid synthesis. UDP-glucose:N-acylsphingosine D-glucosyltransferase (glucosylceramide synthase or ceramide glucosyltransferase) catalyzes the first glycosylation step of glycosphingolipid synthesis. Its product, glucosylceramide, serves as the core of more than 300 glycosphingolipids (GSL). GSLs are a group of membrane components that have the lipid portion embedded in the outer plasma membrane leaflet and the sugar chains extended to the outer environment. Several lines of evidence suggest the importance of GSLs in various cellular processes such as differentiation, adhesion, proliferation, and cell-cell recognition. In pathogenic fungus Cryptococcus neoformans, glucosylceramide serves as an antigen that elicits an antibody response in patients and it is essential for fungal growth in host extracellular environment. | ||
pfam13506 | Glyco_transf_21 | 7.0e-12 | 163 | 336 | 178 | + Glycosyl transferase family 21. This is a family of ceramide beta-glucosyltransferases - EC:2.4.1.80. |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAK73021.1 | 0 | 2 | 569 | 3 | 520 | AF367245_1 ceramide glucosyltransferase [Gossypium arboreum] |
GenBank | ABK95617.1 | 0 | 5 | 569 | 3 | 517 | unknown [Populus trichocarpa] |
RefSeq | NP_565460.1 | 0 | 1 | 569 | 1 | 519 | ceramide glucosyltransferase, putative [Arabidopsis thaliana] |
RefSeq | XP_002329645.1 | 0 | 1 | 568 | 1 | 523 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002514215.1 | 0 | 2 | 568 | 5 | 521 | ceramide glucosyltransferase, putative [Ricinus communis] |