Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000130660 |
Family | GT47 |
Protein Properties | Length: 398 Molecular Weight: 45714.4 Isoelectric Point: 6.0659 |
Chromosome | Chromosome/Scaffold: 01878545 Start: 2739 End: 3989 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 4 | 321 | 0 |
DXPEIFNSDLVKNCKFLTRGTDKPNLCIYFENYGLGPEIENSEGVLSNKSWFSTNQFLLEFIFHNEIKHYKCLTKVSSQASAVYVPFYAGLDASLHLWDS NFTVRDASAKQLVSWLARKPEWAKMWGRDHFLVAGRISWDFRRQTDDVSDWSRSSWNNDIAIPYSTNFHPAEDVDLVQWQSRMRKLERPYLFTFAGAPRP DQQSSIRGKIIDLCVASSRCKLIDCSLGGNIDCDNPSSVTRVFQSSVYCLQPGGDSYTRRSTFDSILAGCIPVFFHPGAAYSQYLWNLPKNHSSYSVYIP VRVADDMPRSIEEILLGI |
Full Sequence |
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Protein Sequence Length: 398 Download |
MHDDXPEIFN SDLVKNCKFL TRGTDKPNLC IYFENYGLGP EIENSEGVLS NKSWFSTNQF 60 LLEFIFHNEI KHYKCLTKVS SQASAVYVPF YAGLDASLHL WDSNFTVRDA SAKQLVSWLA 120 RKPEWAKMWG RDHFLVAGRI SWDFRRQTDD VSDWSRSSWN NDIAIPYSTN FHPAEDVDLV 180 QWQSRMRKLE RPYLFTFAGA PRPDQQSSIR GKIIDLCVAS SRCKLIDCSL GGNIDCDNPS 240 SVTRVFQSSV YCLQPGGDSY TRRSTFDSIL AGCIPVFFHP GAAYSQYLWN LPKNHSSYSV 300 YIPVRVADDM PRSIEEILLG ISKEKELAIR EEVIRLIPNL IYVDPRSRLE TEDAFDLAIK 360 GILERIEDVR KAIREGNDLS IGFADEDSYK YTFHKKQE |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-57 | 36 | 321 | 308 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_193135.2 | 0 | 4 | 398 | 104 | 516 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002280815.1 | 0 | 4 | 393 | 102 | 507 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002300146.1 | 0 | 4 | 393 | 117 | 512 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002321098.1 | 0 | 6 | 390 | 61 | 462 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002532518.1 | 0 | 4 | 393 | 111 | 521 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
CN581993 | 200 | 177 | 376 | 0 |
GO521620 | 192 | 180 | 371 | 0 |
DV145943 | 263 | 48 | 289 | 0 |
ES802449 | 293 | 121 | 393 | 0 |
CV631551 | 168 | 160 | 327 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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