y
Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000131594 |
Family | GT43 |
Protein Properties | Length: 301 Molecular Weight: 34596 Isoelectric Point: 10.3162 |
Chromosome | Chromosome/Scaffold: 02023984 Start: 10815 End: 11714 |
Description | Nucleotide-diphospho-sugar transferases superfamily protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT43 | 208 | 300 | 3.20001e-40 |
LGQLLGLVPRPLLWIVVETNAASMETAEILRKSGVMYRHLVCGNNSTRAKDRGVYQRNTALEHIERHRLDGIVYFADDDNIYSLDLFDRLRDI |
Full Sequence |
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Protein Sequence Length: 301 Download |
MASIRRTLSP AFQDRQYLNG GGSPFSVPSP SQKLLSSSRY SPPFPSAILA FSVSVRSFVA 60 GVLFHRPNRK GQQWRRGFYR CLLFFFLGFL LGLLPFGHVD DDEIRGRSFN FDIKPPHVNV 120 QLDTDNADRA VKXMNVQFNT DNADRAEKRR NVQFDTDNAD RTVKRREDLV DVRLGVVERR 180 VDLVPRKLLI IVTPTYNRAL QAYFLNRLGQ LLGLVPRPLL WIVVETNAAS METAEILRKS 240 GVMYRHLVCG NNSTRAKDRG VYQRNTALEH IERHRLDGIV YFADDDNIYS LDLFDRLRDI 300 X 360 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03360 | Glyco_transf_43 | 1.0e-30 | 208 | 300 | 102 | + Glycosyltransferase family 43. | ||
PLN02458 | PLN02458 | 3.0e-39 | 178 | 300 | 124 | + transferase, transferring glycosyl groups | ||
cd00218 | GlcAT-I | 2.0e-48 | 187 | 300 | 120 | + Beta1,3-glucuronyltransferase I (GlcAT-I) is involved in the initial steps of proteoglycan synthesis. Beta1,3-glucuronyltransferase I (GlcAT-I) domain; GlcAT-I is a Key enzyme involved in the initial steps of proteoglycan synthesis. GlcAT-I catalyzes the transfer of a glucuronic acid moiety from the uridine diphosphate-glucuronic acid (UDP-GlcUA) to the common linkage region of trisaccharide Gal-beta-(1-3)-Gal-beta-(1-4)-Xyl of proteoglycans. The enzyme has two subdomains that bind the donor and acceptor substrate separately. The active site is located at the cleft between both subdomains in which the trisaccharide molecule is oriented perpendicular to the UDP. This family has been classified as Glycosyltransferase family 43 (GT-43). |
Gene Ontology | |
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GO Term | Description |
GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAI93174.2 | 0 | 1 | 300 | 1 | 301 | beta-1,3-glucuronosyltransferase [Medicago truncatula] |
EMBL | CBI19320.1 | 0 | 1 | 300 | 1 | 241 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002283625.1 | 0 | 1 | 300 | 1 | 265 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002301102.1 | 0 | 1 | 300 | 1 | 255 | glycosyl transferase [Populus trichocarpa] |
RefSeq | XP_002510001.1 | 0 | 1 | 299 | 1 | 265 | beta-1,3-glucuronyltransferase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3cu0_B | 0.00000000000003 | 183 | 298 | 14 | 154 | A Chain A, Human Beta 1,3-Glucuronyltransferase I (Glcat-I) In Complex With Udp And Gal-Gal(6-So4)-Xyl(2-Po4)-O-Ser |
PDB | 3cu0_A | 0.00000000000003 | 183 | 298 | 14 | 154 | A Chain A, Human Beta 1,3-Glucuronyltransferase I (Glcat-I) In Complex With Udp And Gal-Gal(6-So4)-Xyl(2-Po4)-O-Ser |
PDB | 1kws_B | 0.00000000000007 | 189 | 298 | 3 | 134 | A Chain A, Human Beta 1,3-Glucuronyltransferase I (Glcat-I) In Complex With Udp And Gal-Gal(6-So4)-Xyl(2-Po4)-O-Ser |
PDB | 1kws_A | 0.00000000000007 | 189 | 298 | 3 | 134 | A Chain A, Human Beta 1,3-Glucuronyltransferase I (Glcat-I) In Complex With Udp And Gal-Gal(6-So4)-Xyl(2-Po4)-O-Ser |
PDB | 1fgg_B | 0.00000000000007 | 189 | 298 | 3 | 134 | A Chain A, Crystal Structure Of 1,3-Glucuronyltransferase I (Glcat-I) Complexed With Gal-Gal-Xyl, Udp, And Mn2+ |