| Basic Information | |
|---|---|
| Species | Malus domestica |
| Cazyme ID | MDP0000138607 |
| Family | GH89 |
| Protein Properties | Length: 443 Molecular Weight: 51099.2 Isoelectric Point: 8.3707 |
| Chromosome | Chromosome/Scaffold: 012292272 Start: 2229 End: 6125 |
| Description | alpha-N-acetylglucosaminidase family / NAGLU family |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH89 | 1 | 437 | 0 |
| MIVLDLFADVKPIWKTSSQFYGTPYIWCLLHNFGGNIEMYGILDAISSGPVDARTSENSTMVGVGMCMEGIEHNPVVYELTSEMAFRSEKVQVQDWLKIY SRRRYGNAVPKVEAAWDILHQTIYNCTDGIASFDASMTLSRLKKGKKHNHALAVSGIVIGWTLFDASMALIMFHDHNTDFIVKLPDWDPSPNHISNISKQ NQMQSFIPLDKKRRVLLQKTSSNLPQAHLWYSTQEVVNALRLFLDTGNEFSGSLTYRYDLVDLTRQVLSKLANQVYLDAVTAYRRRDVKAYSHHSQKFVQ LIMDIDELLASDDNFLLGTWLESAKNLAANPTEMQQYEWNARTQVTMWFDNTKTNQSRLHDYANKFWSGLLKSYYLPRASTYFGLLSKSLRDNKDFELEE WRKEWIAYSNNWQAGTELYRVKAKGDALAISKALYEK | |||
| Full Sequence |
|---|
| Protein Sequence Length: 443 Download |
| MIVLDLFADV KPIWKTSSQF YGTPYIWCLL HNFGGNIEMY GILDAISSGP VDARTSENST 60 MVGVGMCMEG IEHNPVVYEL TSEMAFRSEK VQVQDWLKIY SRRRYGNAVP KVEAAWDILH 120 QTIYNCTDGI ASFDASMTLS RLKKGKKHNH ALAVSGIVIG WTLFDASMAL IMFHDHNTDF 180 IVKLPDWDPS PNHISNISKQ NQMQSFIPLD KKRRVLLQKT SSNLPQAHLW YSTQEVVNAL 240 RLFLDTGNEF SGSLTYRYDL VDLTRQVLSK LANQVYLDAV TAYRRRDVKA YSHHSQKFVQ 300 LIMDIDELLA SDDNFLLGTW LESAKNLAAN PTEMQQYEWN ARTQVTMWFD NTKTNQSRLH 360 DYANKFWSGL LKSYYLPRAS TYFGLLSKSL RDNKDFELEE WRKEWIAYSN NWQAGTELYR 420 VKAKGDALAI SKALYEKYFV RAK 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam05089 | NAGLU | 3.0e-41 | 1 | 90 | 90 | + Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This central domain has a tim barrel fold. | ||
| pfam12972 | NAGLU_C | 4.0e-103 | 95 | 438 | 344 | + Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This C-terminal domain has an all alpha helical fold. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAA77084.1 | 0 | 1 | 439 | 409 | 810 | alpha-N-acetylglucosaminidase [Nicotiana tabacum] |
| EMBL | CBI24942.1 | 0 | 1 | 439 | 471 | 867 | unnamed protein product [Vitis vinifera] |
| GenBank | EEC75285.1 | 0 | 1 | 439 | 420 | 811 | hypothetical protein OsI_11626 [Oryza sativa Indica Group] |
| RefSeq | XP_002273084.1 | 0 | 1 | 439 | 406 | 802 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002314048.1 | 0 | 1 | 439 | 410 | 805 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2vcc_A | 2e-18 | 219 | 440 | 655 | 879 | A Chain A, Peanut Peroxidase |
| PDB | 2vcc_A | 1e-16 | 2 | 124 | 511 | 631 | A Chain A, Peanut Peroxidase |
| PDB | 2vcb_A | 2e-18 | 219 | 440 | 655 | 879 | A Chain A, Peanut Peroxidase |
| PDB | 2vcb_A | 1e-16 | 2 | 124 | 511 | 631 | A Chain A, Peanut Peroxidase |
| PDB | 2vca_A | 2e-18 | 219 | 440 | 655 | 879 | A Chain A, Peanut Peroxidase |
