| Basic Information | |
|---|---|
| Species | Malus domestica |
| Cazyme ID | MDP0000139428 |
| Family | GH31 |
| Protein Properties | Length: 981 Molecular Weight: 112229 Isoelectric Point: 6.6508 |
| Chromosome | Chromosome/Scaffold: 011087269 Start: 5870 End: 11799 |
| Description | Glycosyl hydrolases family 31 protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH31 | 348 | 894 | 0 |
| FFFVGPGPKDVVRQYTSVTGTPAMPQLFAVAYHQCRWNYRDEEDVEQVDSKFDEHDIPYDVLWLDIEHTDGKRYFTWDRMLFPHPEEMQRKLAAKGRHMV TIVDPHIKRDDSYFLHKEATEKQYYVRDATGKDYDGWCWSGSSSYLDMLRPDIRSWWAEKFSYENYVGSTPSLYIWNDMNEPSVFNGPESIRLRFWVGDG SGNALQPPLGAPQPPSLALTTPRRVFAHSHWAEALSLPPRLQSRLGVPRGASFKTLAQTENPEHTNEFNIDFFSLLVTMPRDALHVEGVEHRELHNAYGY YFHMATADGLVKRGDGRDRPFVLSRAVFAGSQRHGAIWTGDNSADWDHLRVSVPMVLTLGITGISFSGADVGGFFGNPEPELLVRWYQLGAYYPFFRAHA HHDTKRREPWILPYLSLKSLNGLYLDYREKNTERIREAIHTRYMLLPYFYTLFREANTTGVPVIRPLWMEFPSEEATFSNDEAFMIGSSLLVQGIYTERA RHASVYLPGKELWYDTKTGVTYKGGKTYKLDVNEESIPAFQRAGTII | |||
| Full Sequence |
|---|
| Protein Sequence Length: 981 Download |
| MKMEMERQIR IPNRNPTVFV FLLLLVXCQL CSVVSWKKEE FRNCNQTPFC KRARGRKPSS 60 SSFAAHDVSI SDGDLTARLV PSDETLEDQD QIKQLILTLS VYQDGILRLR IDEDPKLDPP 120 KKRFEVPXVV MPEFLSKKLW LQRLSTETIG GDASPSSIVY LLDGYEAVLR HDPFEVYVRK 180 KGGNRVVSMN SHGLFDFEQL RVKKDGEDWE ERFKGHTDTR PFGPQSISFD VSFYDADHVY 240 GIPERATSFA LKPTRGPGVE VSEPYRLFNL DVFEYXHDSP FGLYGSIPLM ISHGKSRGTS 300 GFFWLNAAEM QIDVLGTGWD AESGISLPTS QSRIDTHWMS EAGIVDAFFF VGPGPKDVVR 360 QYTSVTGTPA MPQLFAVAYH QCRWNYRDEE DVEQVDSKFD EHDIPYDVLW LDIEHTDGKR 420 YFTWDRMLFP HPEEMQRKLA AKGRHMVTIV DPHIKRDDSY FLHKEATEKQ YYVRDATGKD 480 YDGWCWSGSS SYLDMLRPDI RSWWAEKFSY ENYVGSTPSL YIWNDMNEPS VFNGPESIRL 540 RFWVGDGSGN ALQPPLGAPQ PPSLALTTPR RVFAHSHWAE ALSLPPRLQS RLGVPRGASF 600 KTLAQTENPE HTNEFNIDFF SLLVTMPRDA LHVEGVEHRE LHNAYGYYFH MATADGLVKR 660 GDGRDRPFVL SRAVFAGSQR HGAIWTGDNS ADWDHLRVSV PMVLTLGITG ISFSGADVGG 720 FFGNPEPELL VRWYQLGAYY PFFRAHAHHD TKRREPWILP YLSLKSLNGL YLDYREKNTE 780 RIREAIHTRY MLLPYFYTLF REANTTGVPV IRPLWMEFPS EEATFSNDEA FMIGSSLLVQ 840 GIYTERARHA SVYLPGKELW YDTKTGVTYK GGKTYKLDVN EESIPAFQRA GTIIPRKDRF 900 RRSSTQMVND PYTLFSSECV IERIILQGLS TGHKGALIEP ANQKAEIELG PLLLHSKKGP 960 TAITIRKPNV RVADDWVIKL F |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01055 | Glyco_hydro_31 | 3.0e-71 | 348 | 536 | 189 | + Glycosyl hydrolases family 31. Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases. | ||
| COG1501 | COG1501 | 2.0e-74 | 634 | 914 | 283 | + Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism] | ||
| pfam01055 | Glyco_hydro_31 | 5.0e-98 | 626 | 894 | 273 | + Glycosyl hydrolases family 31. Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases. | ||
| cd06603 | GH31_GANC_GANAB_alpha | 1.0e-101 | 624 | 807 | 184 | + This family includes the closely related glycosyl hydrolase family 31 (GH31) isozymes, neutral alpha-glucosidase C (GANC) and the alpha subunit of heterodimeric neutral alpha-glucosidase AB (GANAB). Initially distinguished on the basis of differences in electrophoretic mobility in starch gel, GANC and GANAB have been shown to have other differences, including those of substrate specificity. GANC and GANAB are key enzymes in glycogen metabolism that hydrolyze terminal, non-reducing 1,4-linked alpha-D-glucose residues from glycogen in the endoplasmic reticulum. The GANC/GANAB family includes the alpha-glucosidase II (ModA) from Dictyostelium discoideum as well as the alpha-glucosidase II (GLS2, or ROT2 - Reversal of TOR2 lethality protein 2) from Saccharomyces cerevisiae. | ||
| cd06603 | GH31_GANC_GANAB_alpha | 6.0e-108 | 367 | 536 | 170 | + This family includes the closely related glycosyl hydrolase family 31 (GH31) isozymes, neutral alpha-glucosidase C (GANC) and the alpha subunit of heterodimeric neutral alpha-glucosidase AB (GANAB). Initially distinguished on the basis of differences in electrophoretic mobility in starch gel, GANC and GANAB have been shown to have other differences, including those of substrate specificity. GANC and GANAB are key enzymes in glycogen metabolism that hydrolyze terminal, non-reducing 1,4-linked alpha-D-glucose residues from glycogen in the endoplasmic reticulum. The GANC/GANAB family includes the alpha-glucosidase II (ModA) from Dictyostelium discoideum as well as the alpha-glucosidase II (GLS2, or ROT2 - Reversal of TOR2 lethality protein 2) from Saccharomyces cerevisiae. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_201189.1 | 0 | 19 | 536 | 4 | 523 | RSW3 (RADIAL SWELLING 3); glucosidase/ hydrolase, hydrolyzing O-glycosyl compounds [Arabidopsis thaliana] |
| RefSeq | XP_002268690.1 | 0 | 31 | 536 | 23 | 529 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002268690.1 | 0 | 624 | 981 | 530 | 926 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002270200.1 | 0 | 31 | 536 | 23 | 529 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002270200.1 | 0 | 624 | 981 | 530 | 926 | PREDICTED: hypothetical protein [Vitis vinifera] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3n04_B | 0 | 283 | 895 | 87 | 617 | A Chain A, The Crystal Structure Of The Alpha-Glucosidase (Family 31) From Ruminococcus Obeum Atcc 29174 |
| PDB | 3n04_A | 0 | 283 | 895 | 87 | 617 | A Chain A, The Crystal Structure Of The Alpha-Glucosidase (Family 31) From Ruminococcus Obeum Atcc 29174 |
| PDB | 3m46_B | 0 | 283 | 895 | 87 | 617 | A Chain A, The Crystal Structure Of The D73a Mutant Of Glycoside Hydrolase (Family 31) From Ruminococcus Obeum Atcc 29174 |
| PDB | 3m46_A | 0 | 283 | 895 | 87 | 617 | A Chain A, The Crystal Structure Of The D73a Mutant Of Glycoside Hydrolase (Family 31) From Ruminococcus Obeum Atcc 29174 |
| PDB | 3nuk_B | 0 | 283 | 895 | 87 | 617 | A Chain A, The Crystal Structure Of The W169y Mutant Of Alpha-Glucosidase (Family 31) From Ruminococcus Obeum Atcc 29174 |
