| Basic Information | |
|---|---|
| Species | Malus domestica |
| Cazyme ID | MDP0000143766 |
| Family | GH47 |
| Protein Properties | Length: 350 Molecular Weight: 39911 Isoelectric Point: 5.8897 |
| Chromosome | Chromosome/Scaffold: 019930248 Start: 3358 End: 7980 |
| Description | alpha-mannosidase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH47 | 11 | 318 | 0 |
| AGSEQLEFIALSQRTKDPKYQQKVEYVIKELHKIFPADGLLPIYINPLTGETSYSKITFGAMGDSFYEYLLKAWIQGNKTEAVKNYREMWETSMKGLKSL IRRTTPSSFAYICEKTGSSLYDKMDELACFAPGMLALGSSGYVPDEAEKFLSLAEELAWTCYNFYQRTPTKLAGENYFFPAGQDMTVGTLWSILRPETIE SLFYLWRFTGNKTYQEWGWNIFQAFENNSRVDSGYSGLKDVGTPTXLIQKQIKGKEKKGKVSTGEKDDMMQSFFLAETLKYLYLLFSPPSFISLDEWVFN TEAHPLRI | |||
| Full Sequence |
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| Protein Sequence Length: 350 Download |
| MSVLKGCNQY AGSEQLEFIA LSQRTKDPKY QQKVEYVIKE LHKIFPADGL LPIYINPLTG 60 ETSYSKITFG AMGDSFYEYL LKAWIQGNKT EAVKNYREMW ETSMKGLKSL IRRTTPSSFA 120 YICEKTGSSL YDKMDELACF APGMLALGSS GYVPDEAEKF LSLAEELAWT CYNFYQRTPT 180 KLAGENYFFP AGQDMTVGTL WSILRPETIE SLFYLWRFTG NKTYQEWGWN IFQAFENNSR 240 VDSGYSGLKD VGTPTXLIQK QIKGKEKKGK VSTGEKDDMM QSFFLAETLK YLYLLFSPPS 300 FISLDEWVFN TEAHPLRITD RHASGESDST TEQDRLPETF QGRKGRSGST 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PTZ00470 | PTZ00470 | 8.0e-110 | 11 | 320 | 317 | + glycoside hydrolase family 47 protein; Provisional | ||
| pfam01532 | Glyco_hydro_47 | 1.0e-121 | 11 | 318 | 324 | + Glycosyl hydrolase family 47. Members of this family are alpha-mannosidases that catalyze the hydrolysis of the terminal 1,2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2). | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity |
| GO:0005509 | calcium ion binding |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI18472.1 | 0 | 11 | 344 | 254 | 568 | unnamed protein product [Vitis vinifera] |
| EMBL | CBI18482.1 | 0 | 11 | 322 | 29 | 320 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002263484.1 | 0 | 11 | 327 | 144 | 440 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002325257.1 | 0 | 11 | 348 | 251 | 570 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002519409.1 | 0 | 11 | 348 | 241 | 556 | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1nxc_A | 0 | 12 | 318 | 176 | 465 | A Chain A, Structure Of Mouse Golgi Alpha-1,2-Mannosidase Ia Reveals The Molecular Basis For Substrate Specificity Among Class I Enzymes (Family 47 Glycosidases) |
| PDB | 1fmi_A | 0 | 13 | 318 | 161 | 456 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo3_A | 0 | 13 | 318 | 161 | 456 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo2_A | 0 | 13 | 318 | 161 | 456 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase In Complex With 1-Deoxymannojirimycin |
| PDB | 1x9d_A | 0 | 13 | 318 | 239 | 534 | A Chain A, Crystal Structure Of Human Class I Alpha-1,2-Mannosidase In Complex With Thio-Disaccharide Substrate Analogue |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| CU615093 | 338 | 11 | 348 | 0 |
| EH768908 | 293 | 29 | 321 | 0 |
| GW895275 | 296 | 11 | 305 | 0 |
| JG883359 | 302 | 12 | 313 | 0 |
| GE608148 | 278 | 37 | 314 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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