Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000148940 |
Family | GT47 |
Protein Properties | Length: 308 Molecular Weight: 34905.5 Isoelectric Point: 10.0089 |
Chromosome | Chromosome/Scaffold: 00841984 Start: 308 End: 2943 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 197 | 307 | 7e-28 |
KRFKIWSYKEGDLPMVHNGPTTYIYSIEGQFIFEXESGPSPFVAQHPDEAHAFFLPXSVSKITDFLYRPHHETFFHRLDRTFTDYIFVVADKYPYWNRSG GADHFFVSCHD |
Full Sequence |
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Protein Sequence Length: 308 Download |
MAEALDFRSP YLLSVTLLLL LVVAVFFSPL NQRHHLSLNL SSSPTSSSSP SNFQHQTTRN 60 FNTTALHAVA PAPSPSPSPT SQPPLELRRR HAPSSTSTAS KLSXATTKKK KSKTERIEEE 120 LGIARAXIRK AILTKNVTSD RKEIYIPRGS VYRNPYAFHQ LNVLVGFLLG GAGTISHSTX 180 VFSLGRFFKM SHVEMMKRFK IWSYKEGDLP MVHNGPTTYI YSIEGQFIFE XESGPSPFVA 240 QHPDEAHAFF LPXSVSKITD FLYRPHHETF FHRLDRTFTD YIFVVADKYP YWNRSGGADH 300 FFVSCHDW |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-10 | 195 | 308 | 124 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI25527.1 | 0 | 112 | 308 | 2 | 168 | unnamed protein product [Vitis vinifera] |
EMBL | CBI25529.1 | 0 | 112 | 308 | 2 | 168 | unnamed protein product [Vitis vinifera] |
EMBL | CBI25537.1 | 0 | 109 | 308 | 83 | 257 | unnamed protein product [Vitis vinifera] |
Swiss-Prot | Q3E9A4 | 0 | 53 | 308 | 27 | 246 | GLYT5_ARATH RecName: Full=Probable glycosyltransferase At5g20260 |
RefSeq | XP_002263848.1 | 0 | 109 | 308 | 2 | 176 | PREDICTED: hypothetical protein [Vitis vinifera] |