| Basic Information | |
|---|---|
| Species | Malus domestica |
| Cazyme ID | MDP0000157943 |
| Family | AA7 |
| Protein Properties | Length: 1016 Molecular Weight: 114528 Isoelectric Point: 9.0495 |
| Chromosome | Chromosome/Scaffold: 000226496 Start: 1220 End: 7996 |
| Description | FAD-binding Berberine family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA7 | 69 | 524 | 0 |
| NLRFNTSTTRKPFLILTALHESHVQISVVCAQIHNLQMKIRSGGHDYEGVSYVAVVPFFILDMFNLRSIHVDIKSKTAWVQAGATLGEVSYRIAEKSKTH GFPAGVGPTVGVGGHFSGGGYGNMMRKYGLSVDNIVDAQLVNVHGELLDRKSMGEDLFWAITGGGGASFGVVIAYKINLVRVPEIVTVFKVPRTLEQNAT DIVYRWQYIADKLDDDLFIRLTMGVVNGTSSNSSGENNKTFTASFIAMFLGDSERLLSIMDKSFPELRLTQSDCTEMSWAQSMLFWSILPTGSATEALLN RTQVRRFFKRKSDYVKKPIPKTGLKWIFKKMIELEKPRLTFNPYGGKMSEISASATPFPHRAGNLWKVQYATDWDIPGTEASDHHIEFTRKLHMYMTPFV SKNPREAFYNYKDLDIGINHNANGMSSYLEGRVYGIKYFKHNFDRLVNVKTKVDPX | |||
| Full Sequence |
|---|
| Protein Sequence Length: 1016 Download |
| MAIPRLPHIX QLSVLLVXST SWATSASADP ENFVHCLLNH SQXSHPIAPA IYSPXNASYS 60 SVLEXYIXNL RFNTSTTRKP FLILTALHES HVQISVVCAQ IHNLQMKIRS GGHDYEGVSY 120 VAVVPFFILD MFNLRSIHVD IKSKTAWVQA GATLGEVSYR IAEKSKTHGF PAGVGPTVGV 180 GGHFSGGGYG NMMRKYGLSV DNIVDAQLVN VHGELLDRKS MGEDLFWAIT GGGGASFGVV 240 IAYKINLVRV PEIVTVFKVP RTLEQNATDI VYRWQYIADK LDDDLFIRLT MGVVNGTSSN 300 SSGENNKTFT ASFIAMFLGD SERLLSIMDK SFPELRLTQS DCTEMSWAQS MLFWSILPTG 360 SATEALLNRT QVRRFFKRKS DYVKKPIPKT GLKWIFKKMI ELEKPRLTFN PYGGKMSEIS 420 ASATPFPHRA GNLWKVQYAT DWDIPGTEAS DHHIEFTRKL HMYMTPFVSK NPREAFYNYK 480 DLDIGINHNA NGMSSYLEGR VYGIKYFKHN FDRLVNVKTK VDPXKAEPPF PSTHTHTQKP 540 KNLHTPSPRR PTSPHLAXAX PVAARLPSPP ATISFGDDKL SRTCPRRQAP VVEPPPSAVC 600 GSWSYDKEYV LKRNLGLGFS RLGCQVVLTP ELQGMVVAVP KDEKKEEKPH EVCDKKTEEV 660 ARENEKEAEE GEEVKKSEDG CEVVDKDISL WGVPLFLGKG FEGIDVVFLK FLRAREFKVN 720 EAFEMLKKTL QWRKESKIDS ILDEDVCADL SFAAYLNGVD REGHPVCYNI FGVFDNEELY 780 QMTFGNEENG GQFLRWRLQL MEKSVQKLDL RPGGVTSLLQ INDLKNSPGP VKKELRIATK 840 QAVGLLQDNY HELVAKKIFI NVPFWYYALN ALLSPFLTQR TKSKFVVARP AKVTETLLKY 900 IPTQEIPAQY GGFKRDNDSE FSAEDGADLC FVCSTLLWDL TVLGWEVNYK EEFVPTDEGS 960 YTIIVQKKKK MGSNESPIRN TLRRNEPGKV VLTIENNSRK KKKVLYRYKA KKCSTL 1020 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG0277 | GlcD | 6.0e-10 | 92 | 274 | 193 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] | ||
| pfam01565 | FAD_binding_4 | 7.0e-13 | 80 | 217 | 141 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. | ||
| pfam00650 | CRAL_TRIO | 2.0e-18 | 754 | 912 | 160 | + CRAL/TRIO domain. | ||
| smart00516 | SEC14 | 1.0e-24 | 758 | 912 | 156 | + Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p). Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p) and in RhoGAPs, RhoGEFs and the RasGAP, neurofibromin (NF1). Lipid-binding domain. The SEC14 domain of Dbl is known to associate with G protein beta/gamma subunits. | ||
| cd00170 | SEC14 | 2.0e-25 | 755 | 912 | 158 | + Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to associate with G protein beta/gamma subunits. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
| GO:0016491 | oxidoreductase activity |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN60572.1 | 0 | 22 | 523 | 22 | 516 | hypothetical protein [Vitis vinifera] |
| EMBL | CAN80091.1 | 0 | 22 | 523 | 22 | 516 | hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002270585.1 | 0 | 22 | 523 | 22 | 516 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002333959.1 | 0 | 15 | 531 | 14 | 531 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523151.1 | 0 | 23 | 531 | 27 | 537 | Reticuline oxidase precursor, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3vte_A | 0 | 28 | 534 | 1 | 517 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
| PDB | 4dns_B | 0 | 31 | 523 | 11 | 483 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 4dns_A | 0 | 31 | 523 | 11 | 483 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 3tsj_B | 0 | 28 | 523 | 6 | 483 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 3tsj_A | 0 | 28 | 523 | 6 | 483 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
