Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000158474 |
Family | AA3 |
Protein Properties | Length: 605 Molecular Weight: 65838.2 Isoelectric Point: 9.786 |
Chromosome | Chromosome/Scaffold: 001635617 Start: 16199 End: 21996 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 35 | 595 | 0 |
SGHNNGYDYIVVGGGTAGCPLAATLSKNFNVLVLERGGVPFSNANVSFLQNFHIALADTSPTSASQPFVSTDGVINTRARVLGGGSCINAGFYTRASTRL NASCVPHVLKLSSHFYGGRLGSEIVRPNKFIKRVGWDAKIVNESYPWIEKQIVHQPKLEPWQVAIRDSLLSVGVSPFNGFTYDHVYGTKVGGTIYDRFGR RHTSAELLSSGNPQKLTVLVYATVQKIVFDISGKKPRAVGVIFKDEKGNQHQALLADKPQSEVILSTGAIGSPQMLLLSGIGPKADLQKLKIPVVLDNKF VGKGMADNPMNAVFVPSSKPEKQTLIETVGITKMGVYIEGSSGFSQSKDSIQCHHGIMSAEIGQLSTIPPKQRTPEAIQAYIRSKKNLPHEAFRGGFILE KIASPLSKGDLSLVNTNVDDNPSVTFNYFSHPYDLQRCVDGIRMATKVVQSEHFTNYTKCDRQTAEKVLDMSVKANVNLIPKHTNDTKSLEQFCKDTVIT IWHYHGGCHVGTVVSPEHKVLGVDRVRVVDGSTFSESPGTNPQATVMMMGRYFGVKIVRER |
Full Sequence |
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Protein Sequence Length: 605 Download |
MPVSVTAGKG NFYEFRYPFI KRASSFPSVS SSSSSGHNNG YDYIVVGGGT AGCPLAATLS 60 KNFNVLVLER GGVPFSNANV SFLQNFHIAL ADTSPTSASQ PFVSTDGVIN TRARVLGGGS 120 CINAGFYTRA STRLNASCVP HVLKLSSHFY GGRLGSEIVR PNKFIKRVGW DAKIVNESYP 180 WIEKQIVHQP KLEPWQVAIR DSLLSVGVSP FNGFTYDHVY GTKVGGTIYD RFGRRHTSAE 240 LLSSGNPQKL TVLVYATVQK IVFDISGKKP RAVGVIFKDE KGNQHQALLA DKPQSEVILS 300 TGAIGSPQML LLSGIGPKAD LQKLKIPVVL DNKFVGKGMA DNPMNAVFVP SSKPEKQTLI 360 ETVGITKMGV YIEGSSGFSQ SKDSIQCHHG IMSAEIGQLS TIPPKQRTPE AIQAYIRSKK 420 NLPHEAFRGG FILEKIASPL SKGDLSLVNT NVDDNPSVTF NYFSHPYDLQ RCVDGIRMAT 480 KVVQSEHFTN YTKCDRQTAE KVLDMSVKAN VNLIPKHTND TKSLEQFCKD TVITIWHYHG 540 GCHVGTVVSP EHKVLGVDRV RVVDGSTFSE SPGTNPQATV MMMGRYFGVK IVRERLGTAA 600 GSFDV |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
TIGR03970 | Rv0697 | 3.0e-19 | 42 | 343 | 337 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. |
TIGR01810 | betA | 7.0e-26 | 42 | 584 | 601 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. |
COG2303 | BetA | 2.0e-39 | 41 | 595 | 613 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] |
PLN02785 | PLN02785 | 0 | 4 | 601 | 599 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI35951.1 | 0 | 9 | 601 | 29 | 592 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002275841.1 | 0 | 1 | 601 | 12 | 583 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002327436.1 | 0 | 31 | 601 | 7 | 546 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002329018.1 | 0 | 11 | 601 | 28 | 590 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002527404.1 | 0 | 7 | 602 | 31 | 597 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3gdp_B | 0 | 41 | 595 | 27 | 517 | A Chain A, Structure Of The Thermostable Pectate Lyase Pl 47 |
PDB | 3gdp_A | 0 | 41 | 595 | 27 | 517 | A Chain A, Structure Of The Thermostable Pectate Lyase Pl 47 |
PDB | 3gdn_B | 0 | 41 | 595 | 27 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 3gdn_A | 0 | 41 | 595 | 27 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 1ju2_B | 0 | 41 | 595 | 27 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO796743 | 560 | 42 | 601 | 0 |
EX670905 | 327 | 99 | 425 | 0 |
ES808127 | 408 | 167 | 572 | 0 |
HO852522 | 375 | 223 | 597 | 0 |
GE636073 | 284 | 272 | 555 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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