| Basic Information | |
|---|---|
| Species | Malus domestica |
| Cazyme ID | MDP0000167309 |
| Family | GH47 |
| Protein Properties | Length: 630 Molecular Weight: 70267.8 Isoelectric Point: 6.9984 |
| Chromosome | Chromosome/Scaffold: 005651111 Start: 23788 End: 27539 |
| Description | alpha-mannosidase 3 |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GH47 | 141 | 623 | 0 |
| AFIHAWLGYKKYAMGYDELMPVSKRGVDGLGGLGATIVDALDTAMIMGADEVVSEAGLWIETQLSNKINQTGQVNLFETTIRVLGGLLSAYHLSSVENGM DPTHKGPKPVVYLETAKNLADRLLTGFTSSPTAIPFGDIVLRDPSAHPAPDGLSSTSEVSTLQLEFNYLSSVSGDPKYTVESMKVLEHIKTLPKVEGLIP IFISPSTGEFAGENIRLGSRGDSYYEYLLKVWLQKKRESNFTYLRDMYEEAMKGVRHRLVQKSIPNGLVFVGELPFGADSSFSSKMDHLVCFLPGTLALG ATKGLTKEEAMRNNMLNFEDLENLKLAEDLAKTCFEXYSVTSTGLAPEIAYFHTXEFSEGGLDGGNKSSEYMNDIIIKPADRHNLLRPETVESLFVLYRI TEDPKYREWGWQIFEAFEKYTRVDTGGYSSLDDVTSVPPHKRDKMETFFLGETLKYFYLLFGDSSVIPLDKFVFNTEAHPIPI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 630 Download |
| MSSKSLPYSK KDVHYDNAKF RHRSFFKVIT QTLQTSNVKN HCMSCSTGKF LLLLMIFGVA 60 YLMLTHTSPT TDGLVKGGNN GTYEHIKSGG IRFGNIFRKP PRLPPQLPPD EKGSRGNIGL 120 DHRKLNSDPK WIARQQNVKK AFIHAWLGYK KYAMGYDELM PVSKRGVDGL GGLGATIVDA 180 LDTAMIMGAD EVVSEAGLWI ETQLSNKINQ TGQVNLFETT IRVLGGLLSA YHLSSVENGM 240 DPTHKGPKPV VYLETAKNLA DRLLTGFTSS PTAIPFGDIV LRDPSAHPAP DGLSSTSEVS 300 TLQLEFNYLS SVSGDPKYTV ESMKVLEHIK TLPKVEGLIP IFISPSTGEF AGENIRLGSR 360 GDSYYEYLLK VWLQKKRESN FTYLRDMYEE AMKGVRHRLV QKSIPNGLVF VGELPFGADS 420 SFSSKMDHLV CFLPGTLALG ATKGLTKEEA MRNNMLNFED LENLKLAEDL AKTCFEXYSV 480 TSTGLAPEIA YFHTXEFSEG GLDGGNKSSE YMNDIIIKPA DRHNLLRPET VESLFVLYRI 540 TEDPKYREWG WQIFEAFEKY TRVDTGGYSS LDDVTSVPPH KRDKMETFFL GETLKYFYLL 600 FGDSSVIPLD KFVFNTEAHP IPIEGTAKMG |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
 | ||||||||
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PTZ00470 | PTZ00470 | 2.0e-171 | 132 | 623 | 496 | + glycoside hydrolase family 47 protein; Provisional | ||
| pfam01532 | Glyco_hydro_47 | 0 | 141 | 623 | 486 | + Glycosyl hydrolase family 47. Members of this family are alpha-mannosidases that catalyze the hydrolysis of the terminal 1,2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2). | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity |
| GO:0005509 | calcium ion binding |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAG52061.1 | 0 | 110 | 623 | 41 | 557 | AC022455_15 endoplasmic reticulum alpha-mannosidase, putative; 33510-31408 [Arabidopsis thaliana] |
| RefSeq | NP_564345.1 | 0 | 3 | 623 | 2 | 620 | glycoside hydrolase family 47 protein [Arabidopsis thaliana] |
| RefSeq | XP_002275664.1 | 0 | 3 | 628 | 2 | 637 | PREDICTED: similar to glycoside hydrolase family 47 protein [Vitis vinifera] |
| RefSeq | XP_002306001.1 | 0 | 3 | 626 | 2 | 631 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002519694.1 | 0 | 3 | 626 | 2 | 622 | endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1fmi_A | 0 | 134 | 623 | 10 | 456 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo3_A | 0 | 134 | 623 | 10 | 456 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo2_A | 0 | 134 | 623 | 10 | 456 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase In Complex With 1-Deoxymannojirimycin |
| PDB | 1x9d_A | 0 | 134 | 623 | 88 | 534 | A Chain A, Crystal Structure Of Human Class I Alpha-1,2-Mannosidase In Complex With Thio-Disaccharide Substrate Analogue |
| PDB | 1dl2_A | 0 | 135 | 623 | 6 | 494 | A Chain A, Crystal Structure Of Class I Alpha-1,2-Mannosidase From Saccharomyces Cerevisiae At 1.54 Angstrom Resolution |
