| Basic Information | |
|---|---|
| Species | Malus domestica |
| Cazyme ID | MDP0000172457 |
| Family | AA1 |
| Protein Properties | Length: 426 Molecular Weight: 47955.6 Isoelectric Point: 7.5131 |
| Chromosome | Chromosome/Scaffold: 003965146 Start: 18357 End: 20695 |
| Description | Laccase/Diphenol oxidase family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
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| Family | Start | End | Evalue |
| AA1 | 31 | 294 | 0 |
| NQYHWVVKEATYTRLCSSKKILTVNGKFPGPVLRAHKGDTVYVNVHNEGSHNITIHWHGVRQPRNPWSDGPEYITQCPIQPGDNFTQKIIFSXEEGTIWW HAHSDWSRXTVHGAIIVYPKRGASYPFPKPDHEEVPIILGQWWKSDVMAVXEEFVRNXGEPNVSDAHTINGQPGDLYPCSGPDXFKLXVDQNKTXLLRLV NAAMNSILFFSVAQHNLTVVGVDGSYTKPVARDYVTISPGQTMDALLLTNQQVGQYYMAARAYS | |||
| Full Sequence |
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| Protein Sequence Length: 426 Download |
| MWSGKRDXAG IVQILSLLLL YFFXFDCTAS NQYHWVVKEA TYTRLCSSKK ILTVNGKFPG 60 PVLRAHKGDT VYVNVHNEGS HNITIHWHGV RQPRNPWSDG PEYITQCPIQ PGDNFTQKII 120 FSXEEGTIWW HAHSDWSRXT VHGAIIVYPK RGASYPFPKP DHEEVPIILG QWWKSDVMAV 180 XEEFVRNXGE PNVSDAHTIN GQPGDLYPCS GPDXFKLXVD QNKTXLLRLV NAAMNSILFF 240 SVAQHNLTVV GVDGSYTKPV ARDYVTISPG QTMDALLLTN QQVGQYYMAA RAYSSIDILE 300 AYYYHIHGVY KXGFPNSPPL VFNFTGETLP FLVQIPKXAT KVKVIKYGAN VEIVFQGTIV 360 TAPIDHPMHL HGYSFFIVGR GPGNFDEXQD PLNYNLVDPP MRNTATVPIS GWTAIRFKAD 420 NPGKYS |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| TIGR03388 | ascorbase | 2.0e-20 | 342 | 423 | 85 | + L-ascorbate oxidase, plant type. Members of this protein family are the copper-containing enzyme L-ascorbate oxidase (EC 1.10.3.3), also called ascorbase. This family is found in flowering plants, and shows greater sequence similarity to a family of laccases (EC 1.10.3.2) from plants than to other known ascorbate oxidases. | ||
| TIGR03388 | ascorbase | 4.0e-39 | 33 | 281 | 274 | + L-ascorbate oxidase, plant type. Members of this protein family are the copper-containing enzyme L-ascorbate oxidase (EC 1.10.3.3), also called ascorbase. This family is found in flowering plants, and shows greater sequence similarity to a family of laccases (EC 1.10.3.2) from plants than to other known ascorbate oxidases. | ||
| pfam07732 | Cu-oxidase_3 | 1.0e-46 | 36 | 152 | 119 | + Multicopper oxidase. This entry contains many divergent copper oxidase-like domains that are not recognised by the pfam00394 model. | ||
| TIGR03389 | laccase | 1.0e-51 | 295 | 423 | 129 | + laccase, plant. Members of this protein family include the copper-containing enzyme laccase (EC 1.10.3.2), often several from a single plant species, and additional, uncharacterized, closely related plant proteins termed laccase-like multicopper oxidases. This protein family shows considerable sequence similarity to the L-ascorbate oxidase (EC 1.10.3.3) family. Laccases are enzymes of rather broad specificity, and classification of all proteins scoring about the trusted cutoff of this model as laccases may be appropriate. | ||
| TIGR03389 | laccase | 1.0e-145 | 33 | 295 | 263 | + laccase, plant. Members of this protein family include the copper-containing enzyme laccase (EC 1.10.3.2), often several from a single plant species, and additional, uncharacterized, closely related plant proteins termed laccase-like multicopper oxidases. This protein family shows considerable sequence similarity to the L-ascorbate oxidase (EC 1.10.3.3) family. Laccases are enzymes of rather broad specificity, and classification of all proteins scoring about the trusted cutoff of this model as laccases may be appropriate. | ||
| Gene Ontology | |
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| GO Term | Description |
| GO:0005507 | copper ion binding |
| GO:0016491 | oxidoreductase activity |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN63600.1 | 0 | 11 | 423 | 4 | 453 | hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002269593.1 | 0 | 28 | 423 | 520 | 953 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002272618.1 | 0 | 13 | 300 | 7 | 292 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002272618.1 | 3.9937e-43 | 296 | 423 | 393 | 520 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002527126.1 | 0 | 9 | 423 | 7 | 376 | laccase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1gyc_A | 2e-32 | 49 | 425 | 22 | 449 | A Chain A, Crystal Structure Determination At Room Temperature Of A Laccase From Trametes Versicolor In Its Oxidised Form Containing A Full Complement Of Copper Ions |
| PDB | 2hzh_A | 6e-32 | 36 | 425 | 9 | 449 | A Chain A, Crystal Structure Of Laccase From Coriolus Zonatus At 2.6 A Resolution |
| PDB | 2qt6_B | 9e-32 | 49 | 425 | 22 | 448 | A Chain A, Crystal Structure Determination Of A Blue Laccase From Lentinus Tigrinus |
| PDB | 2qt6_A | 9e-32 | 49 | 425 | 22 | 448 | A Chain A, Crystal Structure Determination Of A Blue Laccase From Lentinus Tigrinus |
| PDB | 3kw7_B | 1e-31 | 37 | 425 | 10 | 452 | A Chain A, Crystal Structure Of Lacb From Trametes Sp. Ah28-2 |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| CB974476 | 273 | 27 | 299 | 0 |
| GR998871 | 259 | 31 | 289 | 0 |
| CB974655 | 254 | 27 | 280 | 0 |
| GT002481 | 251 | 31 | 281 | 0 |
| DY327982 | 258 | 37 | 294 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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