Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000203531 |
Family | GT68 |
Protein Properties | Length: 793 Molecular Weight: 89579.8 Isoelectric Point: 7.783 |
Chromosome | Chromosome/Scaffold: 01372078 Start: 4218 End: 8610 |
Description | O-fucosyltransferase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT68 | 475 | 768 | 0 |
NRVLVIPSHKVDYQFSRVLDIDHINKCLGRTVVVTFEELAEKKKNHIHIDKFICYFLHPTPCYVDNEHVKKLKGAGVSMNKLESAWVEDVKKPTKRTVQD VQSKFSSNDDVIAIGDVFFADLEQEWVMQPGGPLAHKCKTLIEPSRLIMLTAQRFIQTFLGKNFVALHFRRHGFLKFCNNKQPSCFYPIPQAADCITRVA QRANAAVIYLSTDAAESETGLLQSLVVVNGKTVPLVKRPARNSAEKWDALLYRHGIEGDAQVEAMLDKTICAMSSVFIGASGSTFTEDILRLRK |
Full Sequence |
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Protein Sequence Length: 793 Download |
MREVVDDVVK LEWXHRIFGF ELNSLAIEKL NPTHTNPDSA ELTISIHLSL QSLIQMGXRP 60 AGVVDLENPW ARSTSYTVVC FXFEHVINXX SKRRKQKVKC GSGEELENLG FKGEGLGLGE 120 NEIRCFXXLA PPHIPPPRGL RLSPLLCVSL TPPISSHISV PPSSDSLTHT EAKRQQESAF 180 SNRQSNCHTA TYIPHCRFPE KPKAPPKMNR LSSSSEDDDD RQNLIDQNDR KLPTPRSTAA 240 AAAFHIADDY DDIDSNSNNR SYNHHQLRRR FTXLKLGDLF NKRSFVVLAI FVPTFFIILF 300 FVTDIKALLF TAGNFSSXPY DSASGKLRES ELRALYLLKQ QQVSLFNLWK QTLPNPTNSS 360 NSTSNHSDST QIPLLDDLKS AVLRQISINR DIQQVLLSPH RTGNSTEPDF RDFGDFENPS 420 LGDRCRTVDQ QFSQRRTIEW KPNSNKYLFA ICVSGQMSNH LICLEKHMFF AALLNRVLVI 480 PSHKVDYQFS RVLDIDHINK CLGRTVVVTF EELAEKKKNH IHIDKFICYF LHPTPCYVDN 540 EHVKKLKGAG VSMNKLESAW VEDVKKPTKR TVQDVQSKFS SNDDVIAIGD VFFADLEQEW 600 VMQPGGPLAH KCKTLIEPSR LIMLTAQRFI QTFLGKNFVA LHFRRHGFLK FCNNKQPSCF 660 YPIPQAADCI TRVAQRANAA VIYLSTDAAE SETGLLQSLV VVNGKTVPLV KRPARNSAEK 720 WDALLYRHGI EGDAQVEAML DKTICAMSSV FIGASGSTFT EDILRLRKDW GSASLCDEYL 780 CQGEDPNFIA ENE |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd11548 | NodZ_like | 0.001 | 613 | 768 | 161 | + Alpha 1,6-fucosyltransferase similar to Bradyrhizobium NodZ. Bradyrhizobium NodZ is an alpha 1,6-fucosyltransferase involved in the biosynthesis of the nodulation factor, a lipo-chitooligosaccharide formed by three-to-six beta-1,4-linked N-acetyl-d-glucosamine (GlcNAc) residues and a fatty acid acyl group attached to the nitrogen atom at the non-reducing end. NodZ transfers L-fucose from the GDP-beta-L-fucose donor to the reducing residue of the chitin oligosaccharide backbone, before the attachment of a fatty acid group. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
cd11296 | O-FucT_like | 3.0e-5 | 447 | 488 | 42 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
pfam10250 | O-FucT | 1.0e-6 | 470 | 760 | 328 | + GDP-fucose protein O-fucosyltransferase. This is a family of conserved proteins representing the enzyme responsible for adding O-fucose to EGF (epidermal growth factor-like) repeats. Six highly conserved cysteines are present in O-FucT-1 as well as a DXD-like motif (ERD), conserved in mammals, Drosophila, and C. elegans. Both features are characteristic of several glycosyltransferase families. The enzyme is a membrane-bound protein released by proteolysis and, as for most glycosyltransferases, is strongly activated by manganese. | ||
cd11298 | O-FucT-2 | 1.0e-7 | 620 | 760 | 145 | + GDP-fucose protein O-fucosyltransferase 2. O-FucT-2 adds O-fucose to thrombospondin type 1 repeats (TSRs), and appears conserved in bilateria. The O-fucosylation of TSRs appears to play a role in regulating secretion of metalloproteases of the ADAMTS superfamily. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
cd11296 | O-FucT_like | 8.0e-17 | 608 | 767 | 170 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAM66093.1 | 0 | 213 | 793 | 4 | 566 | unknown [Arabidopsis thaliana] |
RefSeq | NP_173170.2 | 0 | 213 | 793 | 4 | 564 | unknown protein [Arabidopsis thaliana] |
RefSeq | NP_199853.1 | 0 | 213 | 793 | 4 | 566 | unknown protein [Arabidopsis thaliana] |
RefSeq | XP_002264087.1 | 0 | 214 | 793 | 5 | 559 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002303337.1 | 0 | 321 | 793 | 64 | 527 | predicted protein [Populus trichocarpa] |