Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000206089 |
Family | GT47 |
Protein Properties | Length: 482 Molecular Weight: 55064.5 Isoelectric Point: 7.9002 |
Chromosome | Chromosome/Scaffold: 017562444 Start: 11208 End: 13864 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 89 | 410 | 0 |
RLKVYVYELPSKYNKKILQKDPRCLNHMFAAEIYMHRFLLSSPVRTLNPEEADWFYTPIYPTCDLTPTGLPLPFKSPRMMRSAIQLISTNWPYWNRTEGA NHFFVVPHDFGACFHYQFGQQNLNKRFIHCIQIIICRSNRMLLEEKAIERGILPLLQRATLVQTFGQRNHVCLKDGSITIPPYAPPQKMQAHLIPKQTPR SIFVYFRGLFYDINNDPEGGYYARGARAAVWENFKNNPLFDISTDHPTTYYEDMQRSIFCLCPLGWAPWSPRLVEAVVFGCIPVIIADDIVLPFADAIPW EEIGVFVAEEDVPDLDTILTSI |
Full Sequence |
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Protein Sequence Length: 482 Download |
MDLNILFAAN SENHLRHENP FRFPVXLGVK GSVLTLSFQL GKKRRTQMWV FAVLVVCGLA 60 CGIGADQNVR TERISGSAGD VLEDNPVGRL KVYVYELPSK YNKKILQKDP RCLNHMFAAE 120 IYMHRFLLSS PVRTLNPEEA DWFYTPIYPT CDLTPTGLPL PFKSPRMMRS AIQLISTNWP 180 YWNRTEGANH FFVVPHDFGA CFHYQFGQQN LNKRFIHCIQ IIICRSNRML LEEKAIERGI 240 LPLLQRATLV QTFGQRNHVC LKDGSITIPP YAPPQKMQAH LIPKQTPRSI FVYFRGLFYD 300 INNDPEGGYY ARGARAAVWE NFKNNPLFDI STDHPTTYYE DMQRSIFCLC PLGWAPWSPR 360 LVEAVVFGCI PVIIADDIVL PFADAIPWEE IGVFVAEEDV PDLDTILTSI PPEVVLRKQR 420 LLANPSMKWA MMFPQPEQPG DAFHQILNGL ARKLPHDQSV YMKADEKVLN WTAGPVGDLK 480 PW |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-78 | 89 | 410 | 330 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX33320.1 | 0 | 45 | 482 | 2 | 412 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
RefSeq | NP_174064.1 | 0 | 64 | 482 | 20 | 412 | GUT2; catalytic/ glucuronoxylan glucuronosyltransferase [Arabidopsis thaliana] |
RefSeq | XP_002284685.1 | 0 | 49 | 482 | 6 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002297880.1 | 0 | 45 | 482 | 2 | 412 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002304637.1 | 0 | 45 | 482 | 2 | 413 | predicted protein [Populus trichocarpa] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
GO868810 | 357 | 102 | 458 | 0 |
EX131890 | 334 | 91 | 424 | 0 |
ES900637 | 333 | 150 | 482 | 0 |
GO846508 | 350 | 133 | 482 | 0 |
GO872051 | 351 | 100 | 450 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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