| Basic Information | |
|---|---|
| Species | Malus domestica |
| Cazyme ID | MDP0000230907 |
| Family | GT48 |
| Protein Properties | Length: 2124 Molecular Weight: 244016 Isoelectric Point: 9.3389 |
| Chromosome | Chromosome/Scaffold: 010281291 Start: 4666 End: 22819 |
| Description | glucan synthase-like 12 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT48 | 1117 | 1880 | 0 |
| VPSNLEARRRISFFSNSLFMDMPPSPKVRNMLSFSVLTPYYTEEVLFSLRDLEVPNEDGVSILFYLQKIYPDEWNNFLQRVNCTSEEELKGSDELEEELR LWASYRGQTLTRTVRGLMYYRKALELQSFLDMAQDDDLMEGYKAIELNSEDQLKEGRSLWAQCQAVADLKFTYVVSCQLYGIHKRSGDPRAQDILRLMTT YPSLRVAYIDEVEEPSKDSSKKMNQKVYYSTLVKAALPKSIDSSEPVQNLDQGNCSLSFKVIYRIKLPGPAILGEGKPENQNHAIIFTRGEGLQTIDMNQ DNYMEEALKMRNLLQEFLEKHDGVRHPTILGLREHIFTGSVSSLAWFMSNQENSFVTIGQRLLANPLKVRFHYGHPDVFDRLFHLTRGGVSKASKVINLS EDIFAGFNSTLREGNVTHHEYIQVGKGRDVGLNQISMFEAKIANGNGEQTLSRDIYRLGHRFDFFRMMSCYFTTIGFYYSTLITVLTVYVFLYGRLYLVL SGLEEGLSTQRAIRDNKPLQVALASQAFVQIGFLMALPMLMEIGLEKGFRTALSEFVLMQLQLAPVFFTFSLGTKTHYYGRTLLHGGAKYRSTGRGFVVF HAKFADNYRLYSRSHFVKGIELLILLVVYQIFGHTYRSAVAYILITASMWFMVCTWLFAPFLFNPSGFEWQKIVDDWTDWNKWISNRGGIGVPPEKSWES WWEEEQEHLRYSGKRGIAAEILLSLRFFIYQYGLVYHLNIAKHTKSVMVYGISWLVIVLILFVM | |||
| Full Sequence |
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| Protein Sequence Length: 2124 Download |
| MASSSRGGGS EQPPQQPLQR RITRTQTAGN LGETAFDSEV VPSSLVEIAP ILRVANEVES 60 HNPRVAYLCR FYAFEKAHRL DPTSSGRGVR QFKTALLQRL ERVTIMDPLL CXSEXYRSIT 120 THTQCQENLG LRAENDPTLK GKGLKKXMHV KCRASTISTT KNIFKLCQIL IRLTGGFHWK 180 IVGLVRGSAY AQLTKAYQTA NVLFEVLKAV TMTQSMEVDR EILEAHDKVT EKTQLLVPYN 240 ILPLDPDSAN QAIMKYPEVQ AAVFALRNTR GLPRPKDDNK KNEEDILDWL QSMFGFQKDN 300 VANQREHLIL LLANVHIRQF PKPDQQPKLD DRALTEVMKK LFKNYKKWCK LPTIQQEVQQ 360 RKLLYMGLYL LIWGEAANLR FMPECLCYIY HHMAFELYGM LAGNVSPMTG ENVKPAYGGE 420 DEAFLRKVVT PIYEVIAKSG TSVLKNGLHL AFLNPAGQEA ERSKRGKSKH SQWRNYDDLN 480 EYFWSVDCFR LGWPMRAGAD FFCMPIDQRH FDKINEDKKP ASGDRWVGKV NFVEIRSFWH 540 IFRSFDRMWS FFILCLQVMI IVAWNGSGQP TALFNGDVFT KALSVFITAA VLKLGQAFLD 600 VILSWKGRRS MSFHVKLRYI LKVITAAGWV VILPITYAYS WKNPPAFAQT IKSWFGNGGH 660 QPSLFILAVV IYLSPNMLAA VLFLFPFIRR FLERSNYKIV MFMMWWSQPR LYVGRGMHES 720 TFSLFKYTMF WVLLIITKLA FSYYIEVSPL TTLDFSFSLT AKNNIGVVIA LWAPIILVWC 780 ILWIPRFGMP FSPQYLEEFM VHSVVLESSD GLYKLKELHI RTLGMLRSRF QSLPGAFNAR 840 LIPAEKSQPR KKGLKATLSR NFAQVEVNKE KEAARFAQLW NKIISSFREE DLINNREMDL 900 LLVPYWADRD LGRLTQWPPF LLASKIPIAL DMAKDSNGKD KELKKRIEAD NYMSCAVLEC 960 YASFRNIIKL LVQGEREKEV IDYIFSEVEK RIEVGDLMVE YKMSALPSLY DQFVKLIKHL 1020 LDNNKDERDQ VVILFQDMLE VVTRDIMMED HISSLVDSIH GASGYEGMMP LDQPQQYQLF 1080 ASSGAIRFPI QQVTEAWKEK IKRLDLLLTT KESAMDVPSN LEARRRISFF SNSLFMDMPP 1140 SPKVRNMLSF SVLTPYYTEE VLFSLRDLEV PNEDGVSILF YLQKIYPDEW NNFLQRVNCT 1200 SEEELKGSDE LEEELRLWAS YRGQTLTRTV RGLMYYRKAL ELQSFLDMAQ DDDLMEGYKA 1260 IELNSEDQLK EGRSLWAQCQ AVADLKFTYV VSCQLYGIHK RSGDPRAQDI LRLMTTYPSL 1320 RVAYIDEVEE PSKDSSKKMN QKVYYSTLVK AALPKSIDSS EPVQNLDQGN CSLSFKVIYR 1380 IKLPGPAILG EGKPENQNHA IIFTRGEGLQ TIDMNQDNYM EEALKMRNLL QEFLEKHDGV 1440 RHPTILGLRE HIFTGSVSSL AWFMSNQENS FVTIGQRLLA NPLKVRFHYG HPDVFDRLFH 1500 LTRGGVSKAS KVINLSEDIF AGFNSTLREG NVTHHEYIQV GKGRDVGLNQ ISMFEAKIAN 1560 GNGEQTLSRD IYRLGHRFDF FRMMSCYFTT IGFYYSTLIT VLTVYVFLYG RLYLVLSGLE 1620 EGLSTQRAIR DNKPLQVALA SQAFVQIGFL MALPMLMEIG LEKGFRTALS EFVLMQLQLA 1680 PVFFTFSLGT KTHYYGRTLL HGGAKYRSTG RGFVVFHAKF ADNYRLYSRS HFVKGIELLI 1740 LLVVYQIFGH TYRSAVAYIL ITASMWFMVC TWLFAPFLFN PSGFEWQKIV DDWTDWNKWI 1800 SNRGGIGVPP EKSWESWWEE EQEHLRYSGK RGIAAEILLS LRFFIYQYGL VYHLNIAKHT 1860 KSVMVYGISW LVIVLILFVM KTVSVGRRKF SADFQLVFRL IKGLIFITFV SILITLIVLP 1920 HMTLQDIIVC ILAFMPTGWG MLLIAQACKP VVHRAGLWPS VRTLARGFEI VMGLLLFTPV 1980 AFLAWFPFVS EFQTRMLFNQ AFSRGCDQAN GRSYPLDHAS MRETVMCSPS ARSYLLTSGF 2040 CCVSFKIAIA WKPLMEKIRL WKSIRSIALL YDAWMGMLIF IPIALSSWFP FVSTFQTRLM 2100 FNQAFARGLE ISLVLAGNKH NTGI |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam04652 | DUF605 | 5.0e-6 | 48 | 102 | 55 | + Vta1 like. Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ATPase that is required in the multivesicular body (MVB) sorting pathway to dissociate the endosomal sorting complex required for transport (ESCRT). Vta1 promotes correct assembly of Vps4 and stimulates its ATPase activity through its conserved Vta1/SBP1/LIP5 region. | ||
| pfam14288 | FKS1_dom1 | 2.0e-55 | 360 | 496 | 138 | + 1,3-beta-glucan synthase subunit FKS1, domain-1. The FKS1_dom1 domain is likely to be the 'Class I' region just N-terminal to the first set of transmembrane helices that is involved in 1,3-beta-glucan synthesis itself. This family is found on proteins with family Glucan_synthase, pfam02364. | ||
| pfam02364 | Glucan_synthase | 0 | 1117 | 1879 | 827 | + 1,3-beta-glucan synthase component. This family consists of various 1,3-beta-glucan synthase components including Gls1, Gls2 and Gls3 from yeast. 1,3-beta-glucan synthase EC:2.4.1.34 also known as callose synthase catalyzes the formation of a beta-1,3-glucan polymer that is a major component of the fungal cell wall. The reaction catalyzed is:- UDP-glucose + {(1,3)-beta-D-glucosyl}(N) <=> UDP + {(1,3)-beta-D-glucosyl}(N+1). | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0000148 | 1,3-beta-D-glucan synthase complex |
| GO:0003843 | 1,3-beta-D-glucan synthase activity |
| GO:0006075 | (1->3)-beta-D-glucan biosynthetic process |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI16456.1 | 0 | 1 | 2005 | 1 | 1928 | unnamed protein product [Vitis vinifera] |
| EMBL | CBI16456.1 | 0.001 | 2050 | 2121 | 1870 | 1941 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002283298.1 | 0 | 1 | 2005 | 1 | 1927 | PREDICTED: similar to Callose synthase 3 [Vitis vinifera] |
| RefSeq | XP_002528124.1 | 0 | 1 | 2005 | 1 | 1935 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
| RefSeq | XP_002528124.1 | 0.0001 | 2016 | 2121 | 1849 | 1948 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
