Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000236768 |
Family | GH28 |
Protein Properties | Length: 1021 Molecular Weight: 110935 Isoelectric Point: 7.0369 |
Chromosome | Chromosome/Scaffold: 003279119 Start: 5606 End: 13485 |
Description | transducin family protein / WD-40 repeat family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GH28 | 22 | 309 | 0 |
GRRYGSLINGYMLRDVVITGDNGTINGQGSVWWDWFSSKSLNYSRPHLVEFVMSKYVVVSNLTFVNAPAYNIHPVYCSNVHVHNISVSAPPDSPHTVGIV PDSSDIVCIEDCSIGMGYDAIALKSGWDEYGIAYGRPTANVHIRRVTLQSATGSSLAFGSEMSGGISNVLVEKVRLNNSFSGIQFRTTKGRGGYIKDVII SDVEMENIYMAFGASGQFGSHPDDKYDPNALPVLDHITLQGVVGTNITIAGCFTGIKESPFTSFFLSNISLSLNSASPTTWNCSYVSG |
Full Sequence |
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Protein Sequence Length: 1021 Download |
DPSHWEIVEP LPSYGRGIEL PGRRYGSLIN GYMLRDVVIT GDNGTINGQG SVWWDWFSSK 60 SLNYSRPHLV EFVMSKYVVV SNLTFVNAPA YNIHPVYCSN VHVHNISVSA PPDSPHTVGI 120 VPDSSDIVCI EDCSIGMGYD AIALKSGWDE YGIAYGRPTA NVHIRRVTLQ SATGSSLAFG 180 SEMSGGISNV LVEKVRLNNS FSGIQFRTTK GRGGYIKDVI ISDVEMENIY MAFGASGQFG 240 SHPDDKYDPN ALPVLDHITL QGVVGTNITI AGCFTGIKES PFTSFFLSNI SLSLNSASPT 300 TWNCSYVSGS SESVFPEPCS DLNTSYSNPS SARFSLLTLN GKAACPCAKI LLSSGTSGFN 360 GFNSKKSKCI GYTEEQENPV IVKLLFAVVG NMSGESWYGK KGKSGIKLYN GVFVAKRSPD 420 GVQSXSGLVR HQLRRRSNQG NIWDTVKGQV QTEFTDIVAS EDTSIYAKRE RGHLSVDYTC 480 MKWFSSERKV ANLKKRKLGS SFLVLGTGGG DVLALDVAAG HLKWRVNDCH AGGVSSISFA 540 RNTSCLYTAG ADGMICQIDS LTGNLSGKFK ASTKAISSMS VSSNGXILAT AAAQMKIFNL 600 SDHKKIQKFS GHPGAVRCMX FTEDGKYILS SAVGERYIAV WSIDGGKKQS ASVVLKMEHP 660 AXFVDSRCID SGENIEELRS AKPTKISLSS EDILSTTYKG ALPTIFAAVI QGIAKAASGQ 720 VFVAYGSPVK PSFQKXLVHS GTDIKLSSSH DGVLLPMSQS LVKSKKGQNV QNRVIALDRA 780 NAEEALHPMP KVFDSHEKKK RHDKLSFGQD EEMADLDDSR GRAGLVKSKD DMVELEADTX 840 AICMEDRLKA LGILSKVDDH TFNSTLNSAT FKGIDLQRNM XHKKMREAVL SLEPSDACKL 900 LGVLVATWQT RSSSGNNVLP WIYSILVNHG HDIMSQKSET QMLSSLLKVT KSRGAAIQPL 960 LQVSGRLQLV MAQIDKATHA KTQISSHEHE MDESEDDDED VNEIHYGEEN DDSDISSDDD 1020 Q |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd00200 | WD40 | 2.0e-12 | 500 | 647 | 150 | + WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment. | ||
PLN02218 | PLN02218 | 8.0e-19 | 41 | 229 | 196 | + polygalacturonase ADPG | ||
PLN03003 | PLN03003 | 7.0e-20 | 37 | 229 | 197 | + Probable polygalacturonase At3g15720 | ||
pfam00295 | Glyco_hydro_28 | 5.0e-21 | 36 | 266 | 239 | + Glycosyl hydrolases family 28. Glycosyl hydrolase family 28 includes polygalacturonase EC:3.2.1.15 as well as rhamnogalacturonase A(RGase A), EC:3.2.1.-. These enzymes is important in cell wall metabolism. | ||
COG5434 | PGU1 | 6.0e-30 | 36 | 243 | 216 | + Endopygalactorunase [Cell envelope biogenesis, outer membrane] |
Gene Ontology | |
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GO Term | Description |
GO:0004650 | polygalacturonase activity |
GO:0005515 | protein binding |
GO:0005975 | carbohydrate metabolic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN79552.1 | 0 | 442 | 1020 | 31 | 691 | hypothetical protein [Vitis vinifera] |
EMBL | CBI22945.1 | 0 | 442 | 1020 | 31 | 627 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002271327.1 | 0 | 442 | 1020 | 31 | 630 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002315482.1 | 0 | 442 | 1020 | 33 | 616 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002516984.1 | 0 | 442 | 982 | 31 | 575 | nucleotide binding protein, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3jur_D | 1e-21 | 17 | 223 | 107 | 345 | A Chain A, The Crystal Structure Of A Hyperthermoactive Exopolygalacturonase From Thermotoga Maritima |
PDB | 3jur_C | 1e-21 | 17 | 223 | 107 | 345 | A Chain A, The Crystal Structure Of A Hyperthermoactive Exopolygalacturonase From Thermotoga Maritima |
PDB | 3jur_B | 1e-21 | 17 | 223 | 107 | 345 | A Chain A, The Crystal Structure Of A Hyperthermoactive Exopolygalacturonase From Thermotoga Maritima |
PDB | 3jur_A | 1e-21 | 17 | 223 | 107 | 345 | A Chain A, The Crystal Structure Of A Hyperthermoactive Exopolygalacturonase From Thermotoga Maritima |
PDB | 1bhe_A | 0.000000000007 | 44 | 229 | 117 | 304 | A Chain A, Polygalacturonase From Erwinia Carotovora Ssp. Carotovora |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO797483 | 345 | 1 | 345 | 0 |
CV713222 | 255 | 10 | 264 | 0 |
EY698033 | 283 | 4 | 281 | 0 |
JG465096 | 250 | 19 | 268 | 0 |
DY261990 | 266 | 1 | 265 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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