| Basic Information | |
|---|---|
| Species | Malus domestica |
| Cazyme ID | MDP0000239688 |
| Family | GT31 |
| Protein Properties | Length: 854 Molecular Weight: 95687.8 Isoelectric Point: 8.0468 |
| Chromosome | Chromosome/Scaffold: 009277486 Start: 3172 End: 15576 |
| Description | Galactosyltransferase family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT31 | 129 | 324 | 0 |
| NREAIRKAWMPTGEALKRLADEKGIIVRFVIGRSPNRGDSLDKEIDKENDRTNDFIILDDQVEASEERPKKTKLLYIHAVENWDAEFYVKVNDDVYVNLD VLGATLTTYIDKPRVYIGCMKSGEVFSEPTHKWYEPDWWKFGDAKSYFRHASGELYAISRALAQFISINRSILHAYAHDDVSAGSWFIGLDVKHID | |||
| Full Sequence |
|---|
| Protein Sequence Length: 854 Download |
| MHSRPSHNRL SGSAFHSRIS ALLLAMVSTM AAIYVAGRLW QDAADRVYLI QELDKRNGQG 60 QSAIAVDDTL KIIDCREQQK QLSALEMQLA GARQEGFIPK SLSKNEGAHS KKKLVAVIGI 120 ITTFGRKKNR EAIRKAWMPT GEALKRLADE KGIIVRFVIG RSPNRGDSLD KEIDKENDRT 180 NDFIILDDQV EASEERPKKT KLLYIHAVEN WDAEFYVKVN DDVYVNLDVL GATLTTYIDK 240 PRVYIGCMKS GEVFSEPTHK WYEPDWWKFG DAKSYFRHAS GELYAISRAL AQFISINRSI 300 LHAYAHDDVS AGSWFIGLDV KHIDERKFCC SSWMPDRYNI EKRRPREGDH RPMSLHAEHF 360 TQRNNGSESM QSAENDVKVH TQVSPTTKGE TNENSKSVSG TAPPAVGYVG ASLRPPYETI 420 GISTAFVAPS AGSGLPFGAP VLDERQMKRE KRKQANRESA RRSRLRKQAE YEELVKTCES 480 LNAEKMALQS KIKKLKEDSE TLRLENAALR VLLNVLVEFL ELLEKLKNAQ AVTQGGIASV 540 KIEVDLELPN DAKNIISNLG SPHITLGGLK NLINLTSGLR PAGGIQGIPV SLHGGQVLSW 600 KTERGEELLF TSSKAIFKPP KAVRGGIPIC FPQVGTGSLD QNGFARNRIW AIDNDPPPLH 660 PNDSNGKAYI DLLLKPSDDD LKIWPHSFEF RLRVSLAAEG HLTLISRIRN INSKPFSFSF 720 AFHTYFSISD ISEVRVEGLE TLDYLDNLCQ KERFTEQGDA LTFESEVDRA YLKSSDVIAV 780 FDHEKKRTFT VRKEGLPDVV VWNPWEKSKA MADLGDEEYK QMLCVNGASI EKPITLKPGE 840 EWTGRLELSV VPSS 900 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01762 | Galactosyl_T | 2.0e-26 | 130 | 324 | 201 | + Galactosyltransferase. This family includes the galactosyltransferases UDP-galactose:2-acetamido-2-deoxy-D-glucose3beta-galactosyltransferase and UDP-Gal:beta-GlcNAc beta 1,3-galactosyltranferase. Specific galactosyltransferases transfer galactose to GlcNAc terminal chains in the synthesis of the lacto-series oligosaccharides types 1 and 2. | ||
| pfam01263 | Aldose_epim | 7.0e-56 | 590 | 849 | 305 | + Aldose 1-epimerase. | ||
| COG0676 | COG0676 | 4.0e-57 | 590 | 850 | 265 | + Uncharacterized enzymes related to aldose 1-epimerase [Carbohydrate transport and metabolism] | ||
| PLN03193 | PLN03193 | 4.0e-77 | 80 | 332 | 260 | + beta-1,3-galactosyltransferase; Provisional | ||
| cd09020 | D-hex-6-P-epi_like | 9.0e-99 | 590 | 849 | 265 | + D-hexose-6-phosphate epimerase-like. D-Hexose-6-phosphate epimerase Ymr099c from Saccharomyces cerevisiae belongs to the large superfamily of aldose-1-epimerases. Its active site is very similar to the catalytic site of galactose mutarotase, the best studied member of the superfamily. It also contains the conserved glutamate and histidine residues that have been shown in galactose mutarotase to be critical for catalysis, the glutamate serving as the active site base to initiate the reaction by removing the proton from the C-1 hydroxyl group of the sugar substrate, and the histidine as the active site acid to protonate the C-5 ring oxygen. In addition Ymr099c contains 2 conserved arginine residues which are involved in phosphate binding, and exhibits hexose-6-phosphate mutarotase activity on glucose-6-P, galactose-6-P and mannose-6-P. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003700 | sequence-specific DNA binding transcription factor activity |
| GO:0005975 | carbohydrate metabolic process |
| GO:0006355 | regulation of transcription, DNA-dependent |
| GO:0006486 | protein glycosylation |
| GO:0008378 | galactosyltransferase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAD30015.1 | 0 | 1 | 333 | 1 | 334 | beta 1,3-glycosyltransferase-like protein I [Solanum lycopersicum] |
| EMBL | CBI34443.1 | 0 | 1 | 333 | 1 | 332 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002274812.1 | 0 | 1 | 333 | 1 | 332 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002303622.1 | 0 | 14 | 333 | 16 | 335 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002509913.1 | 0 | 1 | 333 | 1 | 338 | Beta-1,3-galactosyltransferase sqv-2, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2cis_A | 1e-33 | 580 | 844 | 14 | 282 | A Chain A, Crystal Structure Of The Nasturtium Seedling Xyloglucanase Isoform Nxg1 |
| PDB | 2cir_A | 1e-33 | 580 | 844 | 14 | 282 | A Chain A, Structure-Based Functional Annotation: Yeast Ymr099c Codes For A D-Hexose-6-Phosphate Mutarotase. Complex With Glucose-6-Phosphate |
| PDB | 2ciq_A | 1e-33 | 580 | 844 | 14 | 282 | A Chain A, Structure-Based Functional Annotation: Yeast Ymr099c Codes For A D-Hexose-6-Phosphate Mutarot |
| PDB | 2htb_D | 1e-25 | 591 | 833 | 56 | 289 | A Chain A, Structure-Based Functional Annotation: Yeast Ymr099c Codes For A D-Hexose-6-Phosphate Mutarot |
| PDB | 2htb_C | 1e-25 | 591 | 833 | 56 | 289 | A Chain A, Structure-Based Functional Annotation: Yeast Ymr099c Codes For A D-Hexose-6-Phosphate Mutarot |
