Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000241559 |
Family | GT47 |
Protein Properties | Length: 412 Molecular Weight: 47359.2 Isoelectric Point: 6.5043 |
Chromosome | Chromosome/Scaffold: 012592365 Start: 198 End: 4659 |
Description | exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 9 | 115 | 2.20004e-41 |
HFQGGFVRQELFYLLQGEKDVHFTFGSVKKDGVNKASQGMHTSKFCLNIAGDTPSSNRLFDAIASHCVPVIISDEIELPYEDVLDYSEFCIFVRTRDALK KNFLVNL |
Full Sequence |
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Protein Sequence Length: 412 Download |
MALDFLVLHF QGGFVRQELF YLLQGEKDVH FTFGSVKKDG VNKASQGMHT SKFCLNIAGD 60 TPSSNRLFDA IASHCVPVII SDEIELPYED VLDYSEFCIF VRTRDALKKN FLVNLTRNXG 120 RDEWTRMWKR LQEVQKFYEF QFPSKEGDAV QMIWQAVARR VPAIRMKLHK SRRFSHSISR 180 EGKGVSRIPS PSNFCNTRSI LVPTSSRYYC CFGVSYRFSG AGEGEEEXDE EECSFDEAVV 240 LFNTREYYKC HDFLESLWNN AEEPSRTLIH GILQCAVGFH HLFNQNHKGA MMELGEGLCK 300 LRKMNFKSGS PFHEFEQEIS AALDFIYQTQ IELAACTDEV CVTMDQSERS YQLLGRYGAG 360 QLLYTLQRDP NSNRFMYNIV FSPHTSYGGE PLKVKLPTLN ATTQHLLACE YD 420 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
COG1547 | COG1547 | 7.0e-5 | 241 | 297 | 60 | + Predicted metal-dependent hydrolase [General function prediction only] | ||
pfam03745 | DUF309 | 1.0e-15 | 239 | 287 | 49 | + Domain of unknown function (DUF309). This domain is found in eubacterial and archaebacterial proteins of unknown function. The proteins contain a motif HXXXEXX(W/Y) where X can be any amino acid. This motif is likely to be functionally important and may be involved in metal binding. | ||
pfam03016 | Exostosin | 3.0e-24 | 15 | 108 | 94 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX33321.1 | 0 | 7 | 194 | 314 | 508 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
EMBL | CBI31205.1 | 0 | 7 | 194 | 260 | 454 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002268382.1 | 0 | 7 | 194 | 293 | 487 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325457.1 | 0 | 7 | 194 | 268 | 462 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002530948.1 | 0 | 7 | 191 | 305 | 496 | catalytic, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
DN492405 | 183 | 12 | 194 | 0 |
CV129948 | 144 | 51 | 194 | 0 |
CV129076 | 144 | 51 | 194 | 0 |
FQ365203 | 195 | 7 | 194 | 0 |
DK549022 | 185 | 6 | 183 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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