Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000251783 |
Family | AA3 |
Protein Properties | Length: 640 Molecular Weight: 70082.5 Isoelectric Point: 9.7495 |
Chromosome | Chromosome/Scaffold: 018653157 Start: 3491 End: 9113 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 176 | 620 | 0 |
PLQEKYDYIVVGGGTAGCPLAATLSANYSVLLLERGDIPTAYPNVLSNAGILANFMQEDDGKTPAQRFTSEDGVAFVRGRVLGGSNALLEAGVRPDNGLT LDHIKGTKITGTIFDNRGRRHGAVELLNKGHPKNLRVAIHAAVERILFSSKASGLSAKGIIYSDLNGRSHRALIRGKGEVILSAGAIGSPQLLLLSGVGS KSYFSSLKIPVVHPQPYVGQFMRDNPRNYITILPPFQLEPSTAQIAGITSDYYIETFSGLPFSTPAFSLFPNPTIPMTINSTFGHIVVKHPAPLSYGSLK LQSSSDVKVGPNVKFNYFAQKPDLSRCVSAVRKIGDLLKTNSLKPFKTQDLPGEEGFNFFGPSLPMNQSDVASFETFCRNTVATFWHYHGGCLVGRVVDG DLRVMGIKALRVVDGSVFKSLSPGTNPQATLMMLGRYVGLRMLEE |
Full Sequence |
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Protein Sequence Length: 640 Download |
MPRIFGGLAS IYIRRNKTQQ VYAIALRAKE FSEVASKSPK AILWFQSGMK MGKGGYVGAE 60 RPKRCLSGLG GRLDGLGVSN IFWRAAEYGL HSGSGCGFRF SNFYAHRRRR EEEEETNEKN 120 MSCFENNMEK SAIAAILLLL YFFVFCPQPM VHSFATPSDV EDFSYLKFVR NATDLPLQEK 180 YDYIVVGGGT AGCPLAATLS ANYSVLLLER GDIPTAYPNV LSNAGILANF MQEDDGKTPA 240 QRFTSEDGVA FVRGRVLGGS NALLEAGVRP DNGLTLDHIK GTKITGTIFD NRGRRHGAVE 300 LLNKGHPKNL RVAIHAAVER ILFSSKASGL SAKGIIYSDL NGRSHRALIR GKGEVILSAG 360 AIGSPQLLLL SGVGSKSYFS SLKIPVVHPQ PYVGQFMRDN PRNYITILPP FQLEPSTAQI 420 AGITSDYYIE TFSGLPFSTP AFSLFPNPTI PMTINSTFGH IVVKHPAPLS YGSLKLQSSS 480 DVKVGPNVKF NYFAQKPDLS RCVSAVRKIG DLLKTNSLKP FKTQDLPGEE GFNFFGPSLP 540 MNQSDVASFE TFCRNTVATF WHYHGGCLVG RVVDGDLRVM GIKALRVVDG SVFKSLSPGT 600 NPQATLMMLG RYVGLRMLEE RSVCKVVDHN STFQPYIGFL |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
COG2303 | BetA | 2.0e-10 | 179 | 260 | 91 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
TIGR01810 | betA | 1.0e-24 | 262 | 610 | 388 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
COG2303 | BetA | 1.0e-27 | 291 | 621 | 365 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
PLN02785 | PLN02785 | 5.0e-129 | 179 | 621 | 536 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAL11514.1 | 0 | 128 | 628 | 1 | 553 | AF412329_1 R-oxynitrile lyase isoenzyme 1 precursor [Prunus dulcis] |
GenBank | ACY69987.1 | 0 | 148 | 634 | 16 | 549 | mandelonitrile lyase 1 [Eriobotrya japonica] |
DDBJ | BAH23313.1 | 0 | 128 | 637 | 1 | 562 | (R)-hydroxynitrile lyase [Prunus mume] |
DDBJ | BAH23314.1 | 0 | 128 | 637 | 1 | 562 | (R)-hydroxynitrile lyase [Prunus mume] |
Swiss-Prot | O50048 | 0 | 128 | 637 | 1 | 562 | MDL2_PRUSE RecName: Full=(R)-mandelonitrile lyase 2; AltName: Full=Hydroxynitrile lyase 2; Short=(R)-oxynitrilase 2; Flags: Precursor |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3red_L | 0 | 154 | 624 | 1 | 521 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_K | 0 | 154 | 624 | 1 | 521 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_J | 0 | 154 | 624 | 1 | 521 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_I | 0 | 154 | 624 | 1 | 521 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_H | 0 | 154 | 624 | 1 | 521 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
DW341064 | 205 | 409 | 613 | 0 |
EX518322 | 313 | 258 | 566 | 0 |
CN493721 | 192 | 370 | 561 | 0 |
HO796743 | 531 | 182 | 621 | 0 |
CN859999 | 165 | 448 | 612 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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