Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000258512 |
Family | GH19 |
Protein Properties | Length: 218 Molecular Weight: 23381.3 Isoelectric Point: 8.1925 |
Chromosome | Chromosome/Scaffold: 008758143 Start: 226 End: 2652 |
Description | homolog of carrot EP3-3 chitinase |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GH19 | 63 | 155 | 6.2e-22 |
VADIVTPDFFNGIINQASSDCAGKKFYSRNGFLDAVKSYSGFGRLGSADDSKHEIAAFFAHVTHETGRAPFVFVCIIFXKIIYITMLKLHIFC |
Full Sequence |
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Protein Sequence Length: 218 Download |
METKSLIALV VVFVAVAAAA AQQRIQYGYC GSSDEYCGQG CQQGLCTGGT TTHSTPSGTG 60 GSVADIVTPD FFNGIINQAS SDCAGKKFYS RNGFLDAVKS YSGFGRLGSA DDSKHEIAAF 120 FAHVTHETGR APFVFVCIIF XKIIYITMLK LHIFCYCSVE YEVVYNNFKK DINGYWKWFA 180 GNLASGGAAS GSSLLFVYSL DYARTRLASD AKAAKKGG |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam00182 | Glyco_hydro_19 | 3.0e-22 | 66 | 129 | 65 | + Chitinase class I. | ||
cd00325 | chitinase_glyco_hydro_19 | 4.0e-23 | 67 | 129 | 64 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. |
Gene Ontology | |
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GO Term | Description |
GO:0004568 | chitinase activity |
GO:0006032 | chitin catabolic process |
GO:0016998 | cell wall macromolecule catabolic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABK95688.1 | 1.99993e-41 | 4 | 129 | 2 | 140 | unknown [Populus trichocarpa] |
GenBank | ACM45716.1 | 1e-38 | 26 | 130 | 37 | 138 | class IV chitinase [Pyrus pyrifolia] |
RefSeq | XP_002326040.1 | 6e-40 | 26 | 130 | 37 | 136 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002326042.1 | 3.00004e-41 | 4 | 129 | 2 | 140 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002330661.1 | 5.99994e-41 | 26 | 130 | 38 | 139 | predicted protein [Populus trichocarpa] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3hbh_A | 4e-16 | 62 | 129 | 1 | 68 | B Chain B, The Avrptob-Bak1 Complex Reveals Two Structurally Similar Kinaseinteracting Domains In A Single Type Iii Effector |
PDB | 3hbe_X | 4e-16 | 62 | 129 | 1 | 68 | B Chain B, The Avrptob-Bak1 Complex Reveals Two Structurally Similar Kinaseinteracting Domains In A Single Type Iii Effector |
PDB | 3hbd_A | 4e-16 | 62 | 129 | 1 | 68 | A Chain A, Class Iv Chitinase Structure From Picea Abies At 1.8a |
PDB | 2c3e_A | 0.0000000007 | 175 | 210 | 108 | 143 | A Chain A, Class Iv Chitinase Structure From Picea Abies At 1.8a |
PDB | 1okc_A | 0.0000000007 | 175 | 210 | 108 | 143 | A Chain A, Structure Of Mitochondrial AdpATP CARRIER IN COMPLEX WITH Carboxyatractyloside |