Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000258781 |
Family | GT20 |
Protein Properties | Length: 1371 Molecular Weight: 152512 Isoelectric Point: 6.6646 |
Chromosome | Chromosome/Scaffold: 008384173 Start: 5302 End: 13773 |
Description | trehalose-phosphatase/synthase 9 |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT20 | 52 | 545 | 0 |
SSSACRERKIVVANMLPLHAKRDPQTKKWCFSLDEDSILLHLKDGFSSKNEVVYVGSLKAEIDTSEQEEVAQKLLEEFNCVPTFLPSDLQKKFYLGFCKQ QLWPLFHYMLPMCPDHGDRFDRSLWQAYVSANKIFADKVMEVINPEDDCIWVHDYHLMVLPTFLRKRYYRVKLGFFLHSPFPSSEIYRTLPVRDEILRGL LNCDLIGFHTFDYARHFLSCCSRMMGLDYESKRGHIGLDYFGRTVYIKILPVGVHMGRLESVLNLPDTTSKIKEIQEQYKGKKLILGIDDMDIFKGISLK FIALEQLLQQNPELQGNXVLVQIINPARGSGKDVQEAKSETYLTARRINEVYGSPNYEPVVLIDRHVPQYEKTAYYAVAECCIVNAVRDGMNLVPYKYIV CRQGTPPMNKALGMTADSPQTSMLVVSEFIGCSPSLSGAIRVNPWDTDAVADALNLAITMSKSEQQLRHEKHYRYVSSHDVAYWARSFAHDLDR |
Full Sequence |
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Protein Sequence Length: 1371 Download |
MASRSCTNLF DLASGGLLDI PYTPRALPRV MTVPGIISDV DGNSNGDDSD ASSSACRERK 60 IVVANMLPLH AKRDPQTKKW CFSLDEDSIL LHLKDGFSSK NEVVYVGSLK AEIDTSEQEE 120 VAQKLLEEFN CVPTFLPSDL QKKFYLGFCK QQLWPLFHYM LPMCPDHGDR FDRSLWQAYV 180 SANKIFADKV MEVINPEDDC IWVHDYHLMV LPTFLRKRYY RVKLGFFLHS PFPSSEIYRT 240 LPVRDEILRG LLNCDLIGFH TFDYARHFLS CCSRMMGLDY ESKRGHIGLD YFGRTVYIKI 300 LPVGVHMGRL ESVLNLPDTT SKIKEIQEQY KGKKLILGID DMDIFKGISL KFIALEQLLQ 360 QNPELQGNXV LVQIINPARG SGKDVQEAKS ETYLTARRIN EVYGSPNYEP VVLIDRHVPQ 420 YEKTAYYAVA ECCIVNAVRD GMNLVPYKYI VCRQGTPPMN KALGMTADSP QTSMLVVSEF 480 IGCSPSLSGA IRVNPWDTDA VADALNLAIT MSKSEQQLRH EKHYRYVSSH DVAYWARSFA 540 HDLDRACQDH YSKRCWGIGL GLRFRVVSLS PNFRKLSIDH IVSAYKRTNR RAIFLDYDGT 600 VIPEASIIKS PSPEVLALLN SLCKDPKNTV FIVSGRGRXS LSDWFASCET LGIAAEHGYF 660 LRRNRSSEWE TSPVGADLDW KEIVEPVMRL YTEATDGSNI ESKESALVWH HQDADPDFGS 720 CQAKELLDHL ENVLSNEPAV VKRGQHIVEV KPQGVSKGLV AEKILSRMVN DGKAPDFVMC 780 VGDDRSDEDM FESILSTVSS PSLPSPPEIF ACTVGTKPSK AKYYLDDVSD VVKLLQGLAT 840 ASTPKPKHLP HIQLFGVVGS TGRTGVMGRS FLAATLIVLV LFGXVSSAAP TAPAKIVGGF 900 FSNAASAFMK RVWSLKATTK TAVSGRPVMK FESGFNVETV FDGSKLGIEP YTVEVLPSGE 960 LLILDSANSN LYRISSSLSL YSRPKLVAGS SDGNPGHVDG RTREARMNHP RGLTVDDSGN 1020 IYVADTMNMA IRKISNAGVT TIAGGKSGRG GSHVDGPSED AKFSDDFDVV YIGSSCSLLV 1080 IDRGNXAIRE IQLHFDDCAY QYGSGFPLGI AMLIGAGFFG YMLALLQRRV GTIVSSQNDX 1140 EPMKTSIPPS SYQKPLTSVR PPLIPEDEQE KQEEGFLGSL GNLLVNAGAC GMEILGAIFP 1200 GFRKKHLNYQ YQSQQQKHPN SWPVQDSYVI PDEDEPPSIE TRTSTPRKTY PFMAKDAETI 1260 HQLRQSRVFY NGWDNLQQQQ QQQXQXXKQP QQHYHRYQSS TPNTFYEQSS ENTTEVVFGA 1320 VQEQDGKGEA VVIKPIDYGA PHVSITTVSA PESIRTAIPM AIIDHIHKRE A 1380 |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
PLN03063 | PLN03063 | 4.0e-161 | 57 | 843 | 824 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional |
PLN02205 | PLN02205 | 0 | 1 | 842 | 848 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] |
pfam00982 | Glyco_transf_20 | 0 | 58 | 545 | 492 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. |
PRK14501 | PRK14501 | 0 | 59 | 839 | 787 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional |
cd03788 | GT1_TPS | 0 | 61 | 544 | 484 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005515 | protein binding |
GO:0005992 | trehalose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAV65494.1 | 0 | 1 | 854 | 1 | 855 | trehalose 6-phosphate synthase [Gossypium hirsutum] |
GenBank | AAV65495.1 | 0 | 1 | 854 | 1 | 855 | trehalose 6-phosphate synthase [Gossypium hirsutum] |
EMBL | CAN78769.1 | 0 | 1 | 854 | 1 | 851 | hypothetical protein [Vitis vinifera] |
RefSeq | XP_002264873.1 | 0 | 1 | 847 | 1 | 844 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002521023.1 | 0 | 1 | 849 | 1 | 850 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1gz5_D | 0 | 143 | 545 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_C | 0 | 143 | 545 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_B | 0 | 143 | 545 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_A | 0 | 143 | 545 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 2wtx_D | 0 | 143 | 545 | 75 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |