Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000272655 |
Family | AA3 |
Protein Properties | Length: 476 Molecular Weight: 52333.9 Isoelectric Point: 7.5954 |
Chromosome | Chromosome/Scaffold: 003871314 Start: 5994 End: 8210 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 62 | 467 | 0 |
LQEEYDYIVVGVGTAGCPLVTTLSANYSVLLLERGNIPSAYPNVLCQNETLANFMQEDDGKTPVQRFTSEDGVANVRGRILGWSSMINIGIYSRADSEFY EKSGIKLDMNLVNNSYEWVENTVIFRPNVTRWQSVVKDAMLEAGVRPDNGLTLDHILGSKVTGTLLDNRGKRHGAVEHLNKGHPKNLRVAIHATVERIIF SSKASGLSAKGIIYSDSNGRSHRALIRGKGEVILSAGEIGSPQLLLLSGVGPKSYLSSRKIPVVHPQPYVGQFMRDNPRNYITTLAPFQVEPSTAQFVGI TSDYYIETFSGLPFSTQAFSLFPSPTIPMTINSSFGHIIFKFPGPLSYGSLKLQSSYDVKVAPNVVDEDLRVMGIKALRVVDGSVFNLSPGTNPQATLMM LGRYVG |
Full Sequence |
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Protein Sequence Length: 476 Download |
MEKSTTAAIL LLLYFFEFCP QPGVSSFANP SDDLGKYSLK VPLVFQNFSY LKFVCNATDL 60 PLQEEYDYIV VGVGTAGCPL VTTLSANYSV LLLERGNIPS AYPNVLCQNE TLANFMQEDD 120 GKTPVQRFTS EDGVANVRGR ILGWSSMINI GIYSRADSEF YEKSGIKLDM NLVNNSYEWV 180 ENTVIFRPNV TRWQSVVKDA MLEAGVRPDN GLTLDHILGS KVTGTLLDNR GKRHGAVEHL 240 NKGHPKNLRV AIHATVERII FSSKASGLSA KGIIYSDSNG RSHRALIRGK GEVILSAGEI 300 GSPQLLLLSG VGPKSYLSSR KIPVVHPQPY VGQFMRDNPR NYITTLAPFQ VEPSTAQFVG 360 ITSDYYIETF SGLPFSTQAF SLFPSPTIPM TINSSFGHII FKFPGPLSYG SLKLQSSYDV 420 KVAPNVVDED LRVMGIKALR VVDGSVFNLS PGTNPQATLM MLGRYVGVQM LEERSE 480 |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
COG2303 | BetA | 2.0e-6 | 426 | 474 | 49 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] |
PLN02785 | PLN02785 | 5.0e-17 | 426 | 474 | 49 | + Protein HOTHEAD |
TIGR01810 | betA | 6.0e-19 | 67 | 343 | 314 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. |
COG2303 | BetA | 2.0e-28 | 64 | 383 | 360 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] |
PLN02785 | PLN02785 | 6.0e-102 | 8 | 437 | 474 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAL11514.1 | 0 | 1 | 426 | 1 | 412 | AF412329_1 R-oxynitrile lyase isoenzyme 1 precursor [Prunus dulcis] |
GenBank | AAL11514.1 | 0.0000000009 | 426 | 475 | 496 | 545 | AF412329_1 R-oxynitrile lyase isoenzyme 1 precursor [Prunus dulcis] |
DDBJ | BAH23314.1 | 0 | 46 | 427 | 35 | 415 | (R)-hydroxynitrile lyase [Prunus mume] |
Swiss-Prot | P52707 | 0 | 1 | 426 | 1 | 413 | MDL3_PRUSE RecName: Full=(R)-mandelonitrile lyase 3; AltName: Full=Hydroxynitrile lyase 3; Short=(R)-oxynitrilase 3; Flags: Precursor |
Swiss-Prot | P52707 | 0.000000004 | 426 | 475 | 497 | 546 | MDL3_PRUSE RecName: Full=(R)-mandelonitrile lyase 3; AltName: Full=Hydroxynitrile lyase 3; Short=(R)-oxynitrilase 3; Flags: Precursor |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3red_L | 0 | 46 | 426 | 7 | 386 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_L | 0.00000000003 | 426 | 475 | 470 | 519 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_K | 0 | 46 | 426 | 7 | 386 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_K | 0.00000000003 | 426 | 475 | 470 | 519 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |
PDB | 3red_J | 0 | 46 | 426 | 7 | 386 | A Chain A, 3.0 A Structure Of The Prunus Mume Hydroxynitrile Lyase Isozyme-1 |