Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000277711 |
Family | GT4 |
Protein Properties | Length: 1102 Molecular Weight: 125764 Isoelectric Point: 8.3799 |
Chromosome | Chromosome/Scaffold: 005119811 Start: 140 End: 8871 |
Description | sucrose synthase 5 |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT4 | 463 | 628 | 0 |
DRKKPIIFSMARLDIVKNITGLVEWYGKNKRLRNLVNLVVVGGFFDPSKSKDREEIAEIKKMHTLIEKYQLRGQIRWIAAQTDRNRNGELYRCIADTRGA FVQPALYEAFGLTVIEAMNCGLPTFATNQGGPAEIIVDGVSGFHIDPNNGDEASKKIADFFENSKT |
Full Sequence |
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Protein Sequence Length: 1102 Download |
SNDEHVLEVD FRAIDFSTPH LTLSSSVGNG IDYVTKFTTS RLAGKLENAQ PLADYLLSLN 60 HQGEQLILNE TLNTASKLQA ALIVTEVYLS DLPKDTPFQN FELSFKEWGF EKGWGDTAER 120 TKETMKILLE VLQAPDPLNM DRFFSRLPTI FNVVIFSPHG YFGQADVLGL PDTGGQVVYI 180 LDQVKAMEEE LTLRIKQQGL TVKPQILVVT RLIPEARGTK CNQELEPING TKYSNILRVP 240 FRTEKGILRR WVSRFDIYPY LELFTQACFP SIFKFILLEC SIIDFVPYDA TAKILNLMEG 300 KPDLIIGNYT DGNLVASLMA NKLGITQATI AHALEKTKYE DSDINWKELD PKYHFSCQFL 360 ADTISMNATD FVIASTYQEI AGSKDRPGQY ESHTAFTLPG LCRVVSGINV FDPKFNIAAP 420 GADQSVYFPY SDKXKRLTSF YPAIEELLFS KEDXSEHLGF LVDRKKPIIF SMARLDIVKN 480 ITGLVEWYGK NKRLRNLVNL VVVGGFFDPS KSKDREEIAE IKKMHTLIEK YQLRGQIRWI 540 AAQTDRNRNG ELYRCIADTR GAFVQPALYE AFGLTVIEAM NCGLPTFATN QGGPAEIIVD 600 GVSGFHIDPN NGDEASKKIA DFFENSKTDV AYWDRFSKAG LQRIYECYTW KIYANKVLNM 660 GSTYTFWRQL NKEQKQAKQR YIQMFFNLQY RNXVKNVPVP XDEPEQPQTT SRHHKALTVS 720 IAKVVEVVHH YDKDCIPLKY ADNMLAYIQS SKTNKTCIRR LTIPKQMKSP VYIYYQLDHF 780 YQNHRRYVKS RSDKQLRSKS NENKTDDCAP ERYTTKGVIV PCGLVAWSLF NDTYKFSVNN 840 KQLGVSKKDI TWKSDQKNKF GSDVYPKNFQ SEGLIGGAKL NSSIPLSEQE DLMVWMRTAA 900 LPTFRKLYGR IEVDLEADAV VTVTIENNYN TYSFRGNKKL VLSTASWIGG KNYLLGVAYL 960 TVGGLCLFLA LAFLLLYLIK PRYVNYFTGH TVCNDQLKLD SILDNYGKFT LVFLLKWINS 1020 STKPIFSGLL SLYIEHNRQC CIYAQAXTEM CLKLFRPFCA GLLGIYRTCL GTGVHQEDTY 1080 TRSPSMHLSI RFDLFWDNLF CH |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03381 | CDC50 | 1.0e-90 | 717 | 982 | 280 | + LEM3 (ligand-effect modulator 3) family / CDC50 family. Members of this family have been predicted to contain transmembrane helices. The family member LEM3 is a ligand-effect modulator, mutation of which increases glucocorticoid receptor activity in response to dexamethasone and also confers increased activity on other intracellular receptors including the progesterone, oestrogen and mineralocorticoid receptors. LEM3 is thought to affect a downstream step in the glucocorticoid receptor pathway. Factors that modulate ligand responsiveness are likely to contribute to the context-specific actions of the glucocorticoid receptor in mammalian cells. The products of genes YNR048w, YNL323w and YCR094w (CDC50) show redundancy of function and are involved in regulation of transcription via CDC39. CDC39 (also known as NOT1) is normally a negative regulator of transcription either by affecting the general RNA polymerase II machinery or by altering chromatin structure. One function of CDC39 is to block activation of the mating response pathway in the absence of pheromone, and mutation causes arrest in G1 by activation of the pathway. It may be that the cold-sensitive arrest in G1 noticed in CDC50 mutants may be due to inactivation of CDC39. The effects of LEM3 on glucocorticoid receptor activity may also be due to effects on transcription via CDC39. | ||
cd03800 | GT1_Sucrose_synthase | 1.0e-103 | 152 | 658 | 507 | + This family is most closely related to the GT1 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light. | ||
PLN00142 | PLN00142 | 0 | 2 | 696 | 695 | + sucrose synthase | ||
TIGR02470 | sucr_synth | 0 | 1 | 695 | 696 | + sucrose synthase. This model represents sucrose synthase, an enzyme that, despite its name, generally uses rather produces sucrose. Sucrose plus UDP (or ADP) becomes D-fructose plus UDP-glucose (or ADP-glucose), which is then available for cell wall (or starch) biosynthesis. The enzyme is homologous to sucrose phosphate synthase, which catalyzes the penultimate step in sucrose synthesis. Sucrose synthase is found, so far, exclusively in plants and cyanobacteria [Energy metabolism, Biosynthesis and degradation of polysaccharides]. | ||
pfam00862 | Sucrose_synth | 0 | 1 | 450 | 450 | + Sucrose synthase. Sucrose synthases catalyze the synthesis of sucrose from UDP-glucose and fructose. This family includes the bulk of the sucrose synthase protein. However the carboxyl terminal region of the sucrose synthases belongs to the glycosyl transferase family pfam00534. |
Gene Ontology | |
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GO Term | Description |
GO:0005985 | sucrose metabolic process |
GO:0009058 | biosynthetic process |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI27338.1 | 0 | 1 | 707 | 131 | 822 | unnamed protein product [Vitis vinifera] |
EMBL | CBI35298.1 | 0 | 1 | 711 | 132 | 824 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002267020.1 | 0 | 1 | 724 | 131 | 835 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002270861.1 | 0 | 1 | 711 | 132 | 824 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002327452.1 | 0 | 1 | 709 | 128 | 804 | predicted protein [Populus trichocarpa] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3s29_H | 0 | 2 | 705 | 130 | 810 | A Chain A, Structural Insights Into The Processivity Of Endopolygalacturonase I From Aspergillus Niger |
PDB | 3s29_G | 0 | 2 | 705 | 130 | 810 | A Chain A, Structural Insights Into The Processivity Of Endopolygalacturonase I From Aspergillus Niger |
PDB | 3s29_F | 0 | 2 | 705 | 130 | 810 | A Chain A, Structural Insights Into The Processivity Of Endopolygalacturonase I From Aspergillus Niger |
PDB | 3s29_E | 0 | 2 | 705 | 130 | 810 | A Chain A, Structural Insights Into The Processivity Of Endopolygalacturonase I From Aspergillus Niger |
PDB | 3s29_D | 0 | 2 | 705 | 130 | 810 | A Chain A, Structural Insights Into The Processivity Of Endopolygalacturonase I From Aspergillus Niger |