Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000285243 |
Family | GH18 |
Protein Properties | Length: 635 Molecular Weight: 68368.3 Isoelectric Point: 5.0159 |
Chromosome | Chromosome/Scaffold: 00961638 Start: 20067 End: 24921 |
Description | Glycosyl hydrolase family protein with chitinase insertion domain |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GH18 | 43 | 364 | 0 |
ASSIDSTLFTHLFCAFADLNVDTYQVTVSSSNQAQFSSFTQTVQQNNPSVKTLLSIGGGGGAALADTFAAMASQPDRRKSFIDSSISLARSYNFHGLDVD WEYPSTTTHMTNFGTLLTELRAAVANESQTSGNTAXLLTAAVHRSADYYTINYPFESISNSLDWINVMAYDFYGSAWESSRANTGPPAALYNATASQING NAGITSWIGAGVAANKIVLGLPFYGYAWRLVNADDHGLFAPADGPANAGTDGSMVYHQIRDFISQNAAETVYNATVVTNYCYSGTTWIGYDDTESISAKV SYAKEEALLGYFAWQVSGDDSN |
Full Sequence |
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Protein Sequence Length: 635 Download |
MSSKTTTLPL LLSALLFLIQ LNVSAGQAAV KGAYWYWDSG LPASSIDSTL FTHLFCAFAD 60 LNVDTYQVTV SSSNQAQFSS FTQTVQQNNP SVKTLLSIGG GGGAALADTF AAMASQPDRR 120 KSFIDSSISL ARSYNFHGLD VDWEYPSTTT HMTNFGTLLT ELRAAVANES QTSGNTAXLL 180 TAAVHRSADY YTINYPFESI SNSLDWINVM AYDFYGSAWE SSRANTGPPA ALYNATASQI 240 NGNAGITSWI GAGVAANKIV LGLPFYGYAW RLVNADDHGL FAPADGPANA GTDGSMVYHQ 300 IRDFISQNAA ETVYNATVVT NYCYSGTTWI GYDDTESISA KVSYAKEEAL LGYFAWQVSG 360 DDSNWALSQT GDFGEENVEL VKSVANLDFA KAVILGNHDA WHTTQFSGKK KDGVQLQLEC 420 LGEEHVGYRC LDYPTLKLSV VGGRPFSGGG KKLFRQKLLS TRFGVQDMDG SAKRICKAAS 480 GAPDDHLVIF LAHNGPTGLG SNMDDICGKD WVFGGGDHGD PDLAQALSLL KETGKICAPL 540 VVFGHMHKEL ADGNGLRKMI VVGDDKTIYL NGAIVPRVKR LNVEQGTPES CGTMRAFTVV 600 EILNGTVDNI FESWVSVAGN RITLEEEHFL FKSGG |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam00704 | Glyco_hydro_18 | 8.0e-75 | 32 | 361 | 339 | + Glycosyl hydrolases family 18. | ||
TIGR04168 | TIGR04168 | 1.0e-84 | 371 | 626 | 265 | + TIGR04168 family protein. Members of this uncharacterized protein family are restricted, in 49 of 50 genomes, to organisms with a family TIGR04167 radical SAM protein, which occasionally is a selenoprotein. | ||
smart00636 | Glyco_18 | 5.0e-85 | 30 | 361 | 348 | + Glyco_18 domain. | ||
cd07397 | MPP_DevT | 2.0e-93 | 370 | 579 | 210 | + Myxococcus xanthus DevT and related proteins, metallophosphatase domain. DevT is a component in the C-signal response pathway in Myxococcus xanthus that stimulates the developmentally regulated expression of the FruA response regulator protein and is required for methylation of FrzCD during fruiting body formation. DevT mutants having an in-frame deletion in the devT gene, display delayed aggregation and a cell autonomous sporulation defect. DevT belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination. | ||
cd02879 | GH18_plant_chitinase_class_V | 4.0e-129 | 27 | 367 | 346 | + The class V plant chitinases have a glycosyl hydrolase family 18 (GH18) domain, but lack the chitin-binding domain present in other GH18 enzymes. The GH18 domain of the class V chitinases has endochitinase activity in some cases and no catalytic activity in others. Included in this family is a lectin found in black locust (Robinia pseudoacacia) bark, which binds chitin but lacks chitinase activity. Also included is a chitinase-related receptor-like kinase (CHRK1) from tobacco (Nicotiana tabacum), with an N-terminal GH18 domain and a C-terminal kinase domain, which is thought to be part of a plant signaling pathway. The GH18 domain of CHRK1 is expressed extracellularly where it binds chitin but lacks chitinase activity. |
Gene Ontology | |
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GO Term | Description |
GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
GO:0005975 | carbohydrate metabolic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACM45717.1 | 0 | 1 | 369 | 1 | 361 | class V chitinase [Pyrus pyrifolia] |
RefSeq | XP_002309323.1 | 0 | 29 | 420 | 2 | 372 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002309324.1 | 0 | 8 | 368 | 6 | 361 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002336275.1 | 0 | 25 | 371 | 22 | 360 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523517.1 | 0 | 1 | 368 | 1 | 362 | chitinase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3aqu_D | 0 | 27 | 364 | 2 | 333 | A Chain A, Crystal Structure Of A Class V Chitinase From Arabidopsis Thaliana |
PDB | 3aqu_C | 0 | 27 | 364 | 2 | 333 | A Chain A, Crystal Structure Of A Class V Chitinase From Arabidopsis Thaliana |
PDB | 3aqu_B | 0 | 27 | 364 | 2 | 333 | A Chain A, Crystal Structure Of A Class V Chitinase From Arabidopsis Thaliana |
PDB | 3aqu_A | 0 | 27 | 364 | 2 | 333 | A Chain A, Crystal Structure Of A Class V Chitinase From Arabidopsis Thaliana |
PDB | 3alf_A | 0 | 30 | 370 | 4 | 340 | A Chain A, Crystal Structure Of Class V Chitinase From Nicotiana Tobaccum |