| Basic Information | |
|---|---|
| Species | Malus domestica |
| Cazyme ID | MDP0000287243 |
| Family | GT43 |
| Protein Properties | Length: 430 Molecular Weight: 48469.3 Isoelectric Point: 9.8355 |
| Chromosome | Chromosome/Scaffold: 009224310 Start: 19243 End: 23503 |
| Description | Nucleotide-diphospho-sugar transferases superfamily protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT43 | 195 | 342 | 6.2e-28 |
| NVKWFGAVSVGILAHSENTDESSESTVQKKEEGENLSMPIQGPACNSSNKLIGWHTFNTLPYEGKSANYIDDRAPVLPNKLEWAGFVLNSRLLWSEAEDK PEWVNDLDGIGGADELIVSPLFLLKDLSLVEPLGNCGRQVLLWWLRVE | |||
| Full Sequence |
|---|
| Protein Sequence Length: 430 Download |
| MKLSALHQSY LTRRSNSFRG SAPLDSSSDG KSPPTLSWLL LHGLCCLVSL VLGFRFSRLV 60 FFFLFSTSAS NLYPAPFRSV ADLTVRNLEL PANPVQNLEF NLNRNATTAS SSSRVIVGRH 120 GIRIRPWPHP NPTETMKAHR IIETVQREQR RQFGVSNPKT VIAVTPTYAR TFQALHLTGV 180 MHSLMLVPYD VVWINVKWFG AVSVGILAHS ENTDESSEST VQKKEEGENL SMPIQGPACN 240 SSNKLIGWHT FNTLPYEGKS ANYIDDRAPV LPNKLEWAGF VLNSRLLWSE AEDKPEWVND 300 LDGIGGADEL IVSPLFLLKD LSLVEPLGNC GRQVLLWWLR VEARFDSKFP PRWTINPPLE 360 ITVPSKRTPW PDAPPELPSN EKTETAVEEH TVKRPIKIRA PRTKRSSRSK RKHETKTIDM 420 QASARHTEQD |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd00218 | GlcAT-I | 3.0e-9 | 159 | 218 | 60 | + Beta1,3-glucuronyltransferase I (GlcAT-I) is involved in the initial steps of proteoglycan synthesis. Beta1,3-glucuronyltransferase I (GlcAT-I) domain; GlcAT-I is a Key enzyme involved in the initial steps of proteoglycan synthesis. GlcAT-I catalyzes the transfer of a glucuronic acid moiety from the uridine diphosphate-glucuronic acid (UDP-GlcUA) to the common linkage region of trisaccharide Gal-beta-(1-3)-Gal-beta-(1-4)-Xyl of proteoglycans. The enzyme has two subdomains that bind the donor and acceptor substrate separately. The active site is located at the cleft between both subdomains in which the trisaccharide molecule is oriented perpendicular to the UDP. This family has been classified as Glycosyltransferase family 43 (GT-43). | ||
| pfam03360 | Glyco_transf_43 | 3.0e-19 | 195 | 343 | 153 | + Glycosyltransferase family 43. | ||
| cd00218 | GlcAT-I | 4.0e-20 | 196 | 343 | 148 | + Beta1,3-glucuronyltransferase I (GlcAT-I) is involved in the initial steps of proteoglycan synthesis. Beta1,3-glucuronyltransferase I (GlcAT-I) domain; GlcAT-I is a Key enzyme involved in the initial steps of proteoglycan synthesis. GlcAT-I catalyzes the transfer of a glucuronic acid moiety from the uridine diphosphate-glucuronic acid (UDP-GlcUA) to the common linkage region of trisaccharide Gal-beta-(1-3)-Gal-beta-(1-4)-Xyl of proteoglycans. The enzyme has two subdomains that bind the donor and acceptor substrate separately. The active site is located at the cleft between both subdomains in which the trisaccharide molecule is oriented perpendicular to the UDP. This family has been classified as Glycosyltransferase family 43 (GT-43). | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAB16800.1 | 0 | 24 | 368 | 43 | 472 | UDP-glucuronyltransferase-like protein [Arabidopsis thaliana] |
| EMBL | CAI94900.1 | 0 | 1 | 430 | 1 | 491 | glycosyltransferase [Glycine max] |
| RefSeq | NP_195407.2 | 0 | 1 | 368 | 1 | 453 | IRX14 (irregular xylem 14); transferase, transferring glycosyl groups / xylosyltransferase [Arabidopsis thaliana] |
| RefSeq | XP_002306485.1 | 0 | 1 | 210 | 1 | 209 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002306485.1 | 0 | 181 | 430 | 261 | 503 | predicted protein [Populus trichocarpa] |
