| Basic Information | |
|---|---|
| Species | Malus domestica |
| Cazyme ID | MDP0000296747 |
| Family | GH31 |
| Protein Properties | Length: 964 Molecular Weight: 106815 Isoelectric Point: 5.89 |
| Chromosome | Chromosome/Scaffold: 011610336 Start: 11192 End: 26260 |
| Description | heteroglycan glucosidase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH31 | 243 | 568 | 0 |
| SPDGVLISLSHVIGTVFMPPKWSLGYHQCRWSYDSDKKVQEITRTFRAKGIPCDVIWMDIDYMDGFRCFTFDKERFPDPKSLVKGLNQNGIKAIWMLDPG IKQEDGYFVYDSGCKSDVWISRADGRPFVGDVWPGPCVFPDYTQAKVRSWWSNLVKDFTLNGVXGIWNDMNEPAVFKTVTKTMPESNIHKGDDELGGCQN HSHYHNVYGMLMARSTYEGMKLGNEKKRPFVLTRAGFSGSQRYAATWTGDNLSTWEHLHMSISMVLQLGLSGQPLSGPDIGGFGGNATPKLFGRWMGIGS MFPFCRGHSEMDTIDHEPWSFGEEDL | |||
| Full Sequence |
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| Protein Sequence Length: 964 Download |
| MGEVGVAVSG SVVGGGGGSS KFALRHPLSP FAVVGLRNLR ALEFGIITIR KKRSAERLVT 60 ECLVSKMADY KGKAVAADAT SGAMIFEPIV EDGIFRFDCS ANDRNAAHPS VSFTNSKDRE 120 TPIMNHNTPS YVPSFECLLG QQIVKLELPS GTSFYGTGEV SGQLERTGKR VFTWNTDAWG 180 YGPGTTSLYQ SHPWVLAVLP TGEALGILAD TTRRCEIDLR KESMIQFIAP SSYPVVTFGP 240 FASPDGVLIS LSHVIGTVFM PPKWSLGYHQ CRWSYDSDKK VQEITRTFRA KGIPCDVIWM 300 DIDYMDGFRC FTFDKERFPD PKSLVKGLNQ NGIKAIWMLD PGIKQEDGYF VYDSGCKSDV 360 WISRADGRPF VGDVWPGPCV FPDYTQAKVR SWWSNLVKDF TLNGVXGIWN DMNEPAVFKT 420 VTKTMPESNI HKGDDELGGC QNHSHYHNVY GMLMARSTYE GMKLGNEKKR PFVLTRAGFS 480 GSQRYAATWT GDNLSTWEHL HMSISMVLQL GLSGQPLSGP DIGGFGGNAT PKLFGRWMGI 540 GSMFPFCRGH SEMDTIDHEP WSFGEEDLPA LYLQGGAIIP VGPPHQHLGE SDQLEDLTLL 600 VALDEDGKAK GVLYEDDGDG YEFMNGGFLL THYIAELQSS TVTVKVLKTE GSWKRPKRRL 660 HVQLLLGGGA MVDTWGNDGE VLQIVMPSEQ EVGKLVSTSE KQYRTRLETA KPIPDAEVTS 720 AHKGIELSRI PIELKGGDWD IKVVPWIGGR IISMMHRPSG TQWLHSRVDI NGYEEYSGTE 780 YRSAGCTEEY NVTERNLEHA GEEESILLEG DIGGGLVLQR QLHIPKNDPK VFRIDSSIIA 840 CKVGAGSGGY SRLVCLRVHP MFTLLHPTES YVSFTAIDGS KHEIWPESDE QLFQGDLLPN 900 GEWMLIDKCV GLGLVNRFDA SQVYKCLIHW GTGTVNLELW SEDRPVSKQS PLRIAHEYEV 960 VTLP |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| cd06603 | GH31_GANC_GANAB_alpha | 2.0e-117 | 256 | 566 | 315 | + This family includes the closely related glycosyl hydrolase family 31 (GH31) isozymes, neutral alpha-glucosidase C (GANC) and the alpha subunit of heterodimeric neutral alpha-glucosidase AB (GANAB). Initially distinguished on the basis of differences in electrophoretic mobility in starch gel, GANC and GANAB have been shown to have other differences, including those of substrate specificity. GANC and GANAB are key enzymes in glycogen metabolism that hydrolyze terminal, non-reducing 1,4-linked alpha-D-glucose residues from glycogen in the endoplasmic reticulum. The GANC/GANAB family includes the alpha-glucosidase II (ModA) from Dictyostelium discoideum as well as the alpha-glucosidase II (GLS2, or ROT2 - Reversal of TOR2 lethality protein 2) from Saccharomyces cerevisiae. |
| pfam01055 | Glyco_hydro_31 | 3.0e-132 | 236 | 571 | 338 | + Glycosyl hydrolases family 31. Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases. |
| PLN02763 | PLN02763 | 0 | 80 | 566 | 487 | + hydrolase, hydrolyzing O-glycosyl compounds |
| PLN02763 | PLN02763 | 0 | 567 | 961 | 395 | + hydrolase, hydrolyzing O-glycosyl compounds |
| cd06604 | GH31_glucosidase_II_MalA | 0 | 256 | 566 | 312 | + Alpha-glucosidase II (alpha-D-glucoside glucohydrolase) is a glycosyl hydrolase family 31 (GH31) enzyme, found in bacteria and plants, which has exo-alpha-1,4-glucosidase and oligo-1,6-glucosidase activities. Alpha-glucosidase II has been characterized in Bacillus thermoamyloliquefaciens where it forms a homohexamer. This family also includes the MalA alpha-glucosidase from Sulfolobus sulfataricus and the AglA alpha-glucosidase from Picrophilus torridus. MalA is part of the carbohydrate-metabolizing machinery that allows this organism to utilize carbohydrates, such as maltose, as the sole carbon and energy source. |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI37476.1 | 0 | 51 | 566 | 51 | 566 | unnamed protein product [Vitis vinifera] |
| EMBL | CBI37476.1 | 0 | 567 | 964 | 660 | 1057 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002263148.1 | 0 | 84 | 566 | 1 | 482 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002519886.1 | 0 | 67 | 566 | 1 | 500 | neutral alpha-glucosidase ab precursor, putative [Ricinus communis] |
| RefSeq | XP_002519886.1 | 0 | 567 | 960 | 594 | 987 | neutral alpha-glucosidase ab precursor, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2g3n_F | 0 | 143 | 560 | 53 | 490 | A Chain A, Crystal Structure At 1.45- Resolution Of The Major Allergen Endo-Beta-1,3-Glucanase Of Banana As A Molecular Basis For The Latex-Fruit Syndrome |
| PDB | 2g3n_E | 0 | 143 | 560 | 53 | 490 | A Chain A, Crystal Structure At 1.45- Resolution Of The Major Allergen Endo-Beta-1,3-Glucanase Of Banana As A Molecular Basis For The Latex-Fruit Syndrome |
| PDB | 2g3n_D | 0 | 143 | 560 | 53 | 490 | A Chain A, Crystal Structure At 1.45- Resolution Of The Major Allergen Endo-Beta-1,3-Glucanase Of Banana As A Molecular Basis For The Latex-Fruit Syndrome |
| PDB | 2g3n_C | 0 | 143 | 560 | 53 | 490 | A Chain A, Crystal Structure At 1.45- Resolution Of The Major Allergen Endo-Beta-1,3-Glucanase Of Banana As A Molecular Basis For The Latex-Fruit Syndrome |
| PDB | 2g3n_B | 0 | 143 | 560 | 53 | 490 | A Chain A, Crystal Structure At 1.45- Resolution Of The Major Allergen Endo-Beta-1,3-Glucanase Of Banana As A Molecular Basis For The Latex-Fruit Syndrome |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO779383 | 394 | 567 | 960 | 0 |
| HO779383 | 162 | 411 | 566 | 0 |
| EL478108 | 288 | 176 | 463 | 0 |
| EX405960 | 279 | 144 | 422 | 0 |
| GT034868 | 338 | 623 | 960 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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