Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000300397 |
Family | GT2 |
Protein Properties | Length: 876 Molecular Weight: 100043 Isoelectric Point: 9.6383 |
Chromosome | Chromosome/Scaffold: 015316131 Start: 5582 End: 9771 |
Description | Cellulose-synthase-like C6 |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT2 | 235 | 409 | 1.5e-28 |
IPMCNEREVYHQSIAAVCIQDWPNERMLVQVLDDSDDIEVQQLIKAEVNKWQQRGVPILYRHRLIRTGYKAGNLKSAMSCDYVKNYEFVAIFDSDFQPEP EFLKKTIPYFKGNDDLGLVQTRWSFVNKDENLLTRLQNINLSFHFEVEQQVNGVFINFFGFNGTAGVWRIKALEE |
Full Sequence |
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Protein Sequence Length: 876 Download |
MSRAQNHEFQ EWWNKQRQTN HDLLLSSDES SHLLTVDIHS PRPDRTVGKD RSRSARQLSW 60 VCRLKFQQIA ASLASVANSF LVLLLTANRR VTSPDSPADS ASSRLYRAIK VFLVVVLLLL 120 CFELVAYFKG WHFSPPSVRS GELAELVYAN WLHVRVNYLA PPLQSFTNVC IVLFLIQSVD 180 RVVLVLGCFW IKFRRVKPKA VMEYKTTSSP SSSNVEEGNA EKVNLEDYPM VLLQIPMCNE 240 REVYHQSIAA VCIQDWPNER MLVQVLDDSD DIEVQQLIKA EVNKWQQRGV PILYRHRLIR 300 TGYKAGNLKS AMSCDYVKNY EFVAIFDSDF QPEPEFLKKT IPYFKGNDDL GLVQTRWSFV 360 NKDENLLTRL QNINLSFHFE VEQQVNGVFI NFFGFNGTAG VWRIKALEEC GGWLERTTVE 420 DMDVAVRAHL CGWKFIYLND VKCVCELPES YGAYKKQQHR WHSGPMQLFR MCFFDILRSK 480 VSVTKKANLI FLFFLLRKLI LPFYSFTLFC IILPLTMFLP EAQLPAWVVC YVPGIMSVLN 540 ILPAPRSFPF IVPYLLFENT MSVTKFNAMI SGLFQFGSSY EWIVTKKLGR SSETDLIAFE 600 RESVPLVPTT GLHRSASESG LEELTKLETT KKSGKKRRNR LYRKELVIAF VLLTASARSL 660 LSAQGIHFYF LLFQGITFLV VGLDLIGEQV ILIGALKSFS GTLMKVLSLL APCCFWRSAP 720 QMLSNQWRNA NVANCATHHL SVCCMALKTT STPFFSTSGE VIEHLIYSST NPPHPQFLMT 780 KFLSFGIPVT PEAKNSGNGG TIKHLTYSFP DRLMPLGDRH SSKQSTTLFV HATLGQRTRR 840 GWTKHVKFHH VQRNYVKSPG KMLRAKIIDS IRSNIS |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd06435 | CESA_NdvC_like | 1.0e-26 | 233 | 471 | 240 | + NdvC_like proteins in this family are putative bacterial beta-(1,6)-glucosyltransferase. NdvC_like proteins in this family are putative bacterial beta-(1,6)-glucosyltransferase. Bradyrhizobium japonicum synthesizes periplasmic cyclic beta-(1,3),beta-(1,6)-D-glucans during growth under hypoosmotic conditions. Two genes (ndvB, ndvC) are involved in the beta-(1, 3), beta-(1,6)-glucan synthesis. The ndvC mutant strain resulted in synthesis of altered cyclic beta-glucans composed almost entirely of beta-(1, 3)-glycosyl linkages. The periplasmic cyclic beta-(1,3),beta-(1,6)-D-glucans function for osmoregulation. The ndvC mutation also affects the ability of the bacteria to establish a successful symbiotic interaction with host plant. Thus, the beta-glucans may function as suppressors of a host defense response. | ||
cd06423 | CESA_like | 4.0e-27 | 235 | 421 | 187 | + CESA_like is the cellulose synthase superfamily. The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan. | ||
COG1215 | COG1215 | 8.0e-32 | 222 | 471 | 252 | + Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane] | ||
cd06421 | CESA_CelA_like | 2.0e-46 | 235 | 469 | 236 | + CESA_CelA_like are involved in the elongation of the glucan chain of cellulose. Family of proteins related to Agrobacterium tumefaciens CelA and Gluconacetobacter xylinus BscA. These proteins are involved in the elongation of the glucan chain of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues. They are putative catalytic subunit of cellulose synthase, which is a glycosyltransferase using UDP-glucose as the substrate. The catalytic subunit is an integral membrane protein with 6 transmembrane segments and it is postulated that the protein is anchored in the membrane at the N-terminal end. | ||
cd06437 | CESA_CaSu_A2 | 3.0e-103 | 229 | 465 | 237 | + Cellulose synthase catalytic subunit A2 (CESA2) is a catalytic subunit or a catalytic subunit substitute of the cellulose synthase complex. Cellulose synthase (CESA) catalyzes the polymerization reaction of cellulose using UDP-glucose as the substrate. Cellulose is an aggregate of unbranched polymers of beta-1,4-linked glucose residues, which is an abundant polysaccharide produced by plants and in varying degrees by several other organisms including algae, bacteria, fungi, and even some animals. Genomes from higher plants harbor multiple CESA genes. There are ten in Arabidopsis. At least three different CESA proteins are required to form a functional complex. In Arabidopsis, CESA1, 3 and 6 and CESA4, 7 and 8, are required for cellulose biosynthesis during primary and secondary cell wall formation. CESA2 is very closely related to CESA6 and is viewed as a prime substitute for CESA6. They functionally compensate each other. The cesa2 and cesa6 double mutant plants were significantly smaller, while the single mutant plants were almost normal. |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN82493.1 | 0 | 1 | 689 | 66 | 751 | hypothetical protein [Vitis vinifera] |
EMBL | CBI35705.1 | 0 | 1 | 690 | 1 | 629 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_187389.1 | 0 | 1 | 690 | 1 | 681 | ATCSLC6 (CELLULOSE-SYNTHASE LIKE C6); cellulose synthase/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002303072.1 | 0 | 2 | 690 | 3 | 677 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324379.1 | 0 | 9 | 690 | 7 | 691 | predicted protein [Populus trichocarpa] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 4hg6_A | 2e-24 | 226 | 538 | 137 | 458 | B Chain B, Structure Of A Cellulose Synthase - Cellulose Translocation Intermediate |