y
Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000301100 |
Family | GT47 |
Protein Properties | Length: 485 Molecular Weight: 55328.1 Isoelectric Point: 7.8352 |
Chromosome | Chromosome/Scaffold: 01591693 Start: 9311 End: 10768 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 63 | 405 | 0 |
CLNRYIYIHDGLPARFNYDFLNNCESLSPRASSSNKPSMCPQLVNLGLGPDVSKSEGVLSDKSWYQTNPHLLEVIFHNRMKKHECLTSNSNLASAIYVPF YPSMGVGVHLWDSNVEIRDASAKDFVKWISRQPEWRKMWGRDHFFAYGRTAWDFRRQEDDSSDWGSKLRFLPESLNMTILIEGSEWKNDIAIPYPTNFHP TEDSEVVAWQNKVRKQERPYLFTFAGAPRPNLEGSIQGKLIEHCQASNNCNFLHCTEKICGNPITVMRAFQSSVYCLQPVGDSFTRRSAFDAFLAGCIPV FFHPATAYAQYLWYLPKDHTKYSVFIPAKDGNDLKEGRIENIL |
Full Sequence |
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Protein Sequence Length: 485 Download |
MARKLSQEVW VGILVTFYIL CISLFCLRYS TSLGANNVIN LLVNKQVHPT CTMKINHTNS 60 DSCLNRYIYI HDGLPARFNY DFLNNCESLS PRASSSNKPS MCPQLVNLGL GPDVSKSEGV 120 LSDKSWYQTN PHLLEVIFHN RMKKHECLTS NSNLASAIYV PFYPSMGVGV HLWDSNVEIR 180 DASAKDFVKW ISRQPEWRKM WGRDHFFAYG RTAWDFRRQE DDSSDWGSKL RFLPESLNMT 240 ILIEGSEWKN DIAIPYPTNF HPTEDSEVVA WQNKVRKQER PYLFTFAGAP RPNLEGSIQG 300 KLIEHCQASN NCNFLHCTEK ICGNPITVMR AFQSSVYCLQ PVGDSFTRRS AFDAFLAGCI 360 PVFFHPATAY AQYLWYLPKD HTKYSVFIPA KDGNDLKEGR IENILLGISK EKGAAMREEV 420 IRLIPKLVYA DPRGRLKTPD AFDIAVQGML DRIENVRKVM NEGRDPSADF AGLENDKFKF 480 PDSTD 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-56 | 110 | 408 | 315 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_193135.2 | 0 | 9 | 480 | 31 | 511 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002280815.1 | 0 | 60 | 470 | 90 | 497 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002300146.1 | 0 | 8 | 480 | 19 | 512 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002321098.1 | 0 | 40 | 480 | 30 | 465 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002532518.1 | 0 | 8 | 480 | 13 | 521 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |