Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000304104 |
Family | AA2 |
Protein Properties | Length: 847 Molecular Weight: 92088.2 Isoelectric Point: 7.587 |
Chromosome | Chromosome/Scaffold: 016006277 Start: 49671 End: 56836 |
Description | GTP-binding protein, HflX |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA2 | 609 | 829 | 0 |
AIGKDPRVAASLLRLHFHDCFAQGCDASVLLDNSTTILSEKGAGPNVNSLRGFEVIDEIKAELEEACPRTVSCADIVALAARASTVLSDGPNWVLPLGRR DSKTASVKSSNNNIPSPRSNLSTLITAFKRQGLDETDLVALSVCPSRGGDNNITPLDFASPARFDNTYFQLLLMGKGLLTSDQVLLTGNGRKAAELVKTY ADNERLFFQQFAQSMVKMGNI |
Full Sequence |
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Protein Sequence Length: 847 Download |
MSACSCCSLI RSSPLSHDHP ISGPLAKLSR PIFSLSLRKQ YSDAATPRFV VVRAVQPGLG 60 VVEPGDVSVH DPTSIDVVET GNGEVLGVVG GVADAKLEDH KPLAPATRVR KKKEEESGDD 120 NRFKLRNGRE VFEEKAYIVG VEHKRGTADS FGVEESLKEL TQLADTAGLM VVGSTYQKLV 180 SPNSRTYIGS GKVAEIKSAI NALGVETVIF DDELSAGQLR NLEKAFGGEV ALAQMEYQLP 240 RLTKMWTHLE RQAGGQVKGM GEKQIEVDKR ILRTQIGVLK KELESVRKHR KQYRNQRLSV 300 PVPVVSLVGY TNAGKSTLLN QLTGANVLAE DRLFATLDPT TRRVQTKNGK EFLLTDTVGF 360 IQKLPTTVVA AFRATLEEIS ESSLLVHVVD ISHPLAEQQI EAVDKVLSEL DVSAIPKLMV 420 WNKVDKVSDP ESIKLEAEKR DDVICISALS GEGINEFCSA VQEKLKDSMV WVEALIPFEK 480 GELLSTIHKV GMVERTEYTD KGTLVKAHVP LRESKPYTQS LGLELSMAVF RGTFLGLVVV 540 TLVVSATLSA AHPEGFNFGW GSRWGSKPST DHHGGGHAPA GGSHGLFPQF YHSSCPQVND 600 IVISVLQRAI GKDPRVAASL LRLHFHDCFA QGCDASVLLD NSTTILSEKG AGPNVNSLRG 660 FEVIDEIKAE LEEACPRTVS CADIVALAAR ASTVLSDGPN WVLPLGRRDS KTASVKSSNN 720 NIPSPRSNLS TLITAFKRQG LDETDLVALS VCPSRGGDNN ITPLDFASPA RFDNTYFQLL 780 LMGKGLLTSD QVLLTGNGRK AAELVKTYAD NERLFFQQFA QSMVKMGNIN PLTGLKGEVR 840 KNCRRVN |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PRK11058 | PRK11058 | 8.0e-83 | 155 | 504 | 379 | + GTPase HflX; Provisional | ||
cd01878 | HflX | 1.0e-98 | 262 | 465 | 204 | + HflX GTPase family. HflX subfamily. A distinct conserved domain with a glycine-rich segment N-terminal of the GTPase domain characterizes the HflX subfamily. The E. coli HflX has been implicated in the control of the lambda cII repressor proteolysis, but the actual biological functions of these GTPases remain unclear. HflX is widespread, but not universally represented in all three superkingdoms. | ||
cd00693 | secretory_peroxidase | 5.0e-126 | 586 | 846 | 301 | + Horseradish peroxidase and related secretory plant peroxidases. Secretory peroxidases belong to class III of the plant heme-dependent peroxidase superfamily. All members of the superfamily share a heme prosthetic group and catalyze a multistep oxidative reaction involving hydrogen peroxide as the electron acceptor. Class III peroxidases are found in the extracellular space or in the vacuole in plants where they have been implicated in hydrogen peroxide detoxification, auxin catabolism and lignin biosynthesis, and stress response. Class III peroxidases contain four conserved disulphide bridges and two conserved calcium binding sites. | ||
COG2262 | HflX | 6.0e-131 | 133 | 515 | 408 | + GTPases [General function prediction only] | ||
TIGR03156 | GTP_HflX | 8.0e-141 | 135 | 465 | 356 | + GTP-binding protein HflX. This protein family is one of a number of homologous small, well-conserved GTP-binding proteins with pleiotropic effects. Bacterial members are designated HflX, following the naming convention in Escherichia coli where HflX is encoded immediately downstream of the RNA chaperone Hfq, and immediately upstream of HflKC, a membrane-associated protease pair with an important housekeeping function. Over large numbers of other bacterial genomes, the pairing with hfq is more significant than with hflK and hlfC. The gene from Homo sapiens in this family has been named PGPL (pseudoautosomal GTP-binding protein-like) [Unknown function, General]. |
Gene Ontology | |
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GO Term | Description |
GO:0004601 | peroxidase activity |
GO:0005525 | GTP binding |
GO:0005622 | intracellular |
GO:0006979 | response to oxidative stress |
GO:0015093 | ferrous iron transmembrane transporter activity |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI19757.1 | 0 | 15 | 518 | 32 | 553 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_001148067.1 | 0 | 73 | 511 | 69 | 535 | GTP-binding protein hflX [Zea mays] |
RefSeq | NP_200604.1 | 0 | 94 | 512 | 75 | 519 | GTP-binding family protein [Arabidopsis thaliana] |
RefSeq | XP_002281042.1 | 0 | 15 | 518 | 20 | 539 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002510444.1 | 0 | 1 | 518 | 1 | 533 | GTP-binding protein hflx, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1qo4_A | 0 | 590 | 847 | 7 | 304 | A Chain A, Crystal Structure Of Rice Bglu1 E386a Mutant |
PDB | 1pa2_A | 0 | 590 | 847 | 7 | 304 | A Chain A, Arabidopsis Thaliana Peroxidase A2 |
PDB | 4a5g_B | 0 | 581 | 847 | 1 | 305 | A Chain A, Raphanus Sativus Anionic Peroxidase. |
PDB | 4a5g_A | 0 | 581 | 847 | 1 | 305 | A Chain A, Raphanus Sativus Anionic Peroxidase. |
PDB | 1sch_B | 0 | 586 | 847 | 2 | 294 | A Chain A, Peanut Peroxidase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO780001 | 429 | 106 | 508 | 0 |
HO466041 | 430 | 113 | 515 | 0 |
JG865196 | 302 | 127 | 402 | 0 |
EY694209 | 268 | 229 | 496 | 0 |
EY694209 | 41 | 459 | 497 | 0.67 |
Sequence Alignments (This image is cropped. Click for full image.) |
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