| Basic Information | |
|---|---|
| Species | Malus domestica |
| Cazyme ID | MDP0000304346 |
| Family | GT1 |
| Protein Properties | Length: 854 Molecular Weight: 93997.4 Isoelectric Point: 7.0088 |
| Chromosome | Chromosome/Scaffold: 018243204 Start: 857 End: 9152 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT1 | 180 | 582 | 0 |
| VGTRGDVQPFIAIGKRLQDYGHRVRLATHSNFKEFVLTAGLEFYPLGGDPKVLAGYMVKNKGFLPSGPSDIPIQRNQLKEIINSLLPACKEADMDSGIAF KADAIIANPPAYGHTHVAEALKIPIHVFFTMPWTPTSEFPHPLSRVKQTTGYRLSYQIVDSLIWLGIRDMINDLRKKKLKLRPVTYLSGSQGSDSDVPYG YIWSPHLVPKPKDWGPKVDVVGFCFLDLASNYEPPELLVKWLEAGDKPIYIGFGSLPVQEPQKMTQIIVEALERTGQRGIINKGWGGLGELAEPKDFIYL LDNCPHDWLFLQCKAVVHHGGAGTTAAGLKAACPTTIVPFFGDQPFWGERVHARGVGPAPIAVDEFSLPKLVDAINFMLDPRVKERAVELAKAMEKEDGV TGA | |||
| Full Sequence |
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| Protein Sequence Length: 854 Download |
| MEEPPEKRRD SSASSGEVPV RIXDATGGAS SENSVELEKS VDISHGGSCS KGIXGGSLSK 60 GNTLPPAEIS SNSERRESNS VPXKLERSKT DTTRHQNKLS KDAAKIFDDK IPVHQKLKLL 120 NRIATVKDDG TVEFEVPAGV EPQYLGDRXR TASTGVADDE NLDTEDLQDI PPMQIVMLIV 180 GTRGDVQPFI AIGKRLQDYG HRVRLATHSN FKEFVLTAGL EFYPLGGDPK VLAGYMVKNK 240 GFLPSGPSDI PIQRNQLKEI INSLLPACKE ADMDSGIAFK ADAIIANPPA YGHTHVAEAL 300 KIPIHVFFTM PWTPTSEFPH PLSRVKQTTG YRLSYQIVDS LIWLGIRDMI NDLRKKKLKL 360 RPVTYLSGSQ GSDSDVPYGY IWSPHLVPKP KDWGPKVDVV GFCFLDLASN YEPPELLVKW 420 LEAGDKPIYI GFGSLPVQEP QKMTQIIVEA LERTGQRGII NKGWGGLGEL AEPKDFIYLL 480 DNCPHDWLFL QCKAVVHHGG AGTTAAGLKA ACPTTIVPFF GDQPFWGERV HARGVGPAPI 540 AVDEFSLPKL VDAINFMLDP RVKERAVELA KAMEKEDGVT GARINVNGAA AAAEKKKTNL 600 IMCQDKKPLR FAPLKSCRLH GLAHWFSLGQ QCLSISVGDL ISQIVPNMED EEKDVTEVDH 660 QESNAEEDRD ANSRVFPCLF CSRKFYSSQA LGGHQNAHKK ERTAARKAKR ASDYASSMNF 720 PILSHNTQPH MVFTPNYHLG LLHPYITPHA SNLRYFPNPD QFSSDSFGSN GAPKFENLVY 780 YGGNCSSPSN NMNGYQCEED DQSFLNWQRS IRRYNGLSGG GSSQHSSMAN GNHNSGIGGE 840 CKGKEQKLDL SLHL 900 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG1819 | COG1819 | 5.0e-37 | 172 | 583 | 420 | + Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms] | ||
| pfam03033 | Glyco_transf_28 | 1.0e-37 | 175 | 319 | 145 | + Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities. | ||
| cd03784 | GT1_Gtf_like | 6.0e-122 | 173 | 582 | 410 | + This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005975 | carbohydrate metabolic process |
| GO:0008152 | metabolic process |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| GO:0030259 | lipid glycosylation |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAC22616.1 | 0 | 5 | 582 | 2 | 576 | UDP-glucose:sterol 3-O-glucosyltransferase [Panax ginseng] |
| DDBJ | BAC22617.1 | 0 | 9 | 582 | 3 | 569 | UDP-glucose:sterol 3-O-glucosyltransferase [Panax ginseng] |
| EMBL | CBI37267.1 | 0 | 1 | 582 | 1 | 581 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002265023.1 | 0 | 1 | 582 | 48 | 628 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002521125.1 | 0 | 16 | 582 | 19 | 590 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3h4t_A | 7e-30 | 173 | 580 | 1 | 371 | A Chain A, The Structure Of A Putative 4-Hydroxybutyrate Coa-Transferase From Porphyromonas Gingivalis W83 |
| PDB | 3h4i_A | 7e-30 | 173 | 580 | 1 | 371 | A Chain A, Chimeric Glycosyltransferase For The Generation Of Novel Natural Products |
| PDB | 1rrv_B | 2e-22 | 173 | 578 | 1 | 387 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| PDB | 1rrv_A | 2e-22 | 173 | 578 | 1 | 387 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| PDB | 1iir_A | 7e-19 | 417 | 588 | 230 | 397 | A Chain A, Crystal Structure Of Udp-Glucosyltransferase Gtfb |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| GT046352 | 335 | 182 | 516 | 0 |
| GO883166 | 313 | 156 | 468 | 0 |
| DY295142 | 401 | 84 | 484 | 0 |
| CX664063 | 295 | 272 | 566 | 0 |
| GT046352 | 32 | 509 | 540 | 0.0001 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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