Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000304627 |
Family | GT47 |
Protein Properties | Length: 284 Molecular Weight: 32186.8 Isoelectric Point: 9.8501 |
Chromosome | Chromosome/Scaffold: 017711141 Start: 177 End: 2863 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 173 | 283 | 9.9e-27 |
KRFKIWSYKEGDLPMVHNXPTTYIYSIEGQFIFEMESGPSPFVAQQPDXAHASFLPLSVSKITDFLIRPHHETFXHRLDRTFTDYIYVVADKYPYWNRSG GADHFFVSCHD |
Full Sequence |
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Protein Sequence Length: 284 Download |
MAEALDFRSP YLLSVPLLLL LVVAIFFSPL NQRHHLSLNF SSSPTSFSSP SNFQHQTTGN 60 FNTTALHAVA PAPSPSPSPT TQPPLEPRSR HAPSSTSTAS KLSQATTKKK KSKTERIEEE 120 LGIARAIIRK AIXTKNRNKS IHSYHIQLCV NIIPMGGFVR PLILYKSHVE MVKRFKIWSY 180 KEGDLPMVHN XPTTYIYSIE GQFIFEMESG PSPFVAQQPD XAHASFLPLS VSKITDFLIR 240 PHHETFXHRL DRTFTDYIYV VADKYPYWNR SGGADHFFVS CHDW |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 8.0e-9 | 171 | 284 | 124 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI25527.1 | 0 | 112 | 284 | 2 | 168 | unnamed protein product [Vitis vinifera] |
EMBL | CBI25529.1 | 0 | 112 | 284 | 2 | 168 | unnamed protein product [Vitis vinifera] |
Swiss-Prot | Q3E9A4 | 0 | 53 | 284 | 27 | 246 | GLYT5_ARATH RecName: Full=Probable glycosyltransferase At5g20260 |
RefSeq | XP_002263848.1 | 0 | 109 | 284 | 2 | 176 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002515488.1 | 0 | 21 | 284 | 27 | 250 | catalytic, putative [Ricinus communis] |