Basic Information | |
---|---|
Species | Malus domestica |
Cazyme ID | MDP0000304996 |
Family | GT1 |
Protein Properties | Length: 624 Molecular Weight: 69409.5 Isoelectric Point: 6.2661 |
Chromosome | Chromosome/Scaffold: 017855300 Start: 4156 End: 12017 |
Description | UDP-Glycosyltransferase superfamily protein |
View CDS |
External Links |
---|
NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT1 | 203 | 585 | 0 |
PLGGDPRVLAGYMARNKGLIPSGPAEISIQRKQLKAIIESLLPACTEPDIETGVPFKAQAIIANPPAYGELLQVEYXMSLQLNYVSGHAHVAEALGVPLH IFFTMPWTPTYEFPHPLARVPQSAGYWLSYIVVDLLIWWGIRGYINDFRKKKLKLPPIAYFSTYHGSISHLPTGYMWSPHVVPKPSDWGSLVDVVGYCFL NLGSKYQPQDEFVEWIQKGPKPIYIGFGSMPLDDPKKTTDMILEALKDTGQRGIIDRGWGDLGNFTEASDNVFLLEDCPHDWLFPQCSAVVHHGGAGTTA TGLRAGCPTTIVPFFGDQFFWGDRIHEKGLGPAXIPISQLSVESLSNAIRFMLEPEVKSRVLEMAKLIENEDGVAAAVNAFHR |
Full Sequence |
---|
Protein Sequence Length: 624 Download |
MGSNGVDHPL KHLEEEGVSS QGQSSFQGER KQKTXSARPS SVLEIFQEKE FNGASSPWRG 60 LDNSITAPIG TPKGLLIKEH EIRFSRSMME KKGRHDLKLD RLSEREKKKL IVEMVKIQND 120 GRVEVDLEKS APVASELLEL HTVEDVPINL DEMPSNTIKS IPRLKICILV VGTRGDEFGH 180 HVRLATHANF SSFVKSAGVD FYPLGGDPRV LAGYMARNKG LIPSGPAEIS IQRKQLKAII 240 ESLLPACTEP DIETGVPFKA QAIIANPPAY GELLQVEYXM SLQLNYVSGH AHVAEALGVP 300 LHIFFTMPWT PTYEFPHPLA RVPQSAGYWL SYIVVDLLIW WGIRGYINDF RKKKLKLPPI 360 AYFSTYHGSI SHLPTGYMWS PHVVPKPSDW GSLVDVVGYC FLNLGSKYQP QDEFVEWIQK 420 GPKPIYIGFG SMPLDDPKKT TDMILEALKD TGQRGIIDRG WGDLGNFTEA SDNVFLLEDC 480 PHDWLFPQCS AVVHHGGAGT TATGLRAGCP TTIVPFFGDQ FFWGDRIHEK GLGPAXIPIS 540 QLSVESLSNA IRFMLEPEVK SRVLEMAKLI ENEDGVAAAV NAFHRQLPXE LPLQPASSEE 600 VEPPXPMVWL FLQLEKWCCL PCGV |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
TIGR01426 | MGT | 5.0e-6 | 420 | 579 | 162 | + glycosyltransferase, MGT family. This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production [Cellular processes, Toxin production and resistance]. | ||
pfam03033 | Glyco_transf_28 | 2.0e-19 | 166 | 316 | 163 | + Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities. | ||
COG1819 | COG1819 | 9.0e-27 | 163 | 585 | 439 | + Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms] | ||
cd03784 | GT1_Gtf_like | 2.0e-112 | 165 | 585 | 437 | + This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0005975 | carbohydrate metabolic process |
GO:0008152 | metabolic process |
GO:0016758 | transferase activity, transferring hexosyl groups |
GO:0030259 | lipid glycosylation |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABC96116.1 | 0 | 30 | 623 | 109 | 700 | sterol glucosyltransferase [Withania somnifera] |
EMBL | CBI18214.1 | 0 | 1 | 623 | 68 | 697 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002265312.1 | 0 | 1 | 623 | 52 | 681 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002302172.1 | 0 | 1 | 622 | 1 | 615 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002524293.1 | 0 | 58 | 624 | 12 | 579 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3h4t_A | 2e-24 | 413 | 586 | 212 | 384 | A Chain A, Pectin Methylesterase Pema From Erwinia Chrysanthemi |
PDB | 3h4i_A | 2e-24 | 413 | 586 | 212 | 384 | A Chain A, Chimeric Glycosyltransferase For The Generation Of Novel Natural Products |
PDB | 1iir_A | 3e-24 | 413 | 588 | 229 | 403 | A Chain A, Crystal Structure Of Udp-Glucosyltransferase Gtfb |
PDB | 1rrv_B | 9e-22 | 284 | 570 | 104 | 383 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
PDB | 1rrv_A | 9e-22 | 284 | 570 | 104 | 383 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
EST Download unfiltered results here | ||||
---|---|---|---|---|
Hit | Length | Start | End | EValue |
DT547914 | 340 | 170 | 509 | 0 |
HO801427 | 412 | 182 | 586 | 0 |
CO103793 | 291 | 168 | 458 | 0 |
GT172550 | 328 | 139 | 454 | 0 |
GT172550 | 66 | 462 | 522 | 0.31 |
Sequence Alignments (This image is cropped. Click for full image.) |
---|