| Basic Information | |
|---|---|
| Species | Malus domestica |
| Cazyme ID | MDP0000308427 |
| Family | GH47 |
| Protein Properties | Length: 659 Molecular Weight: 74932.7 Isoelectric Point: 6.0294 |
| Chromosome | Chromosome/Scaffold: 019930276 Start: 3357 End: 14134 |
| Description | alpha-mannosidase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH47 | 196 | 627 | 0 |
| AMIHAWTYYEMYAWGHDELKPQTRNSVDSFGGLGATLVDSLDTLYIMGLDQQFQRAREWVANSLNFNKNYEASVFETTIRVIGGLLSAYDLSHDDIFLEK ARDIADRLLPAWNTPSGIPYNIINLMYGDAKNPQWTGGKSILADAGSEQLEFIALSQRTKDPKYQQKVEYVIKELHKIFPADGLLPIYINPLTGETSYSK ITFGAMGDSFYEYLLKAWIQGNKTEAVKNYREMWETSMKGLKSLIRRTTPSSFAYICEKTGSSLYDKMDELACFAPGMLALGSSGYVPDEAEKFLSLAEE LAWTCYNFYQRTPTKLAGENYFFPAGQDMTVGTLWSILRPETIESLFYLWRFTGNKTYQEWGWNIFQAFENNSRVDSGYSGLKDVSTGEKDDMMQSFFLA ETLKYLYLLFSPPSFISLDEWVFNTEAHPLRI | |||
| Full Sequence |
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| Protein Sequence Length: 659 Download |
| MEIFHFDLEI ESSKEGKPIA TKAYLIVIIV LXLRAVPXTL PLLESLTSSC QASGSGNRVK 60 YPVVVKXRXA SKRLTTKRTG EESLSLEIVD LVVKEASKPV SSVATXWWRY LHPXYHLKRS 120 QLLPLIVLSF VALTWLLSAL QSLTGDHQVA VSRLNKELKT LKNQLESVKK HLRGWSIVEE 180 DDDPLNFERR KAVKDAMIHA WTYYEMYAWG HDELKPQTRN SVDSFGGLGA TLVDSLDTLY 240 IMGLDQQFQR AREWVANSLN FNKNYEASVF ETTIRVIGGL LSAYDLSHDD IFLEKARDIA 300 DRLLPAWNTP SGIPYNIINL MYGDAKNPQW TGGKSILADA GSEQLEFIAL SQRTKDPKYQ 360 QKVEYVIKEL HKIFPADGLL PIYINPLTGE TSYSKITFGA MGDSFYEYLL KAWIQGNKTE 420 AVKNYREMWE TSMKGLKSLI RRTTPSSFAY ICEKTGSSLY DKMDELACFA PGMLALGSSG 480 YVPDEAEKFL SLAEELAWTC YNFYQRTPTK LAGENYFFPA GQDMTVGTLW SILRPETIES 540 LFYLWRFTGN KTYQEWGWNI FQAFENNSRV DSGYSGLKDV STGEKDDMMQ SFFLAETLKY 600 LYLLFSPPSF ISLDEWVFNT EAHPLRITDR HASGESDSTT EQDRLPETFQ GRKGRSGST 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01532 | Glyco_hydro_47 | 0 | 196 | 627 | 451 | + Glycosyl hydrolase family 47. Members of this family are alpha-mannosidases that catalyze the hydrolysis of the terminal 1,2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2). | ||
| PTZ00470 | PTZ00470 | 0 | 178 | 629 | 463 | + glycoside hydrolase family 47 protein; Provisional | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity |
| GO:0005509 | calcium ion binding |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI17906.1 | 0 | 107 | 644 | 45 | 585 | unnamed protein product [Vitis vinifera] |
| EMBL | CBI18472.1 | 0 | 108 | 653 | 11 | 568 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002310939.1 | 0 | 108 | 614 | 13 | 524 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002325257.1 | 0 | 111 | 657 | 15 | 570 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002519409.1 | 0 | 119 | 657 | 23 | 556 | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1nxc_A | 0 | 188 | 627 | 19 | 465 | A Chain A, Structure Of Mouse Golgi Alpha-1,2-Mannosidase Ia Reveals The Molecular Basis For Substrate Specificity Among Class I Enzymes (Family 47 Glycosidases) |
| PDB | 1fmi_A | 0 | 185 | 627 | 7 | 456 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo3_A | 0 | 185 | 627 | 7 | 456 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo2_A | 0 | 185 | 627 | 7 | 456 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase In Complex With 1-Deoxymannojirimycin |
| PDB | 1x9d_A | 0 | 185 | 627 | 85 | 534 | A Chain A, Crystal Structure Of Human Class I Alpha-1,2-Mannosidase In Complex With Thio-Disaccharide Substrate Analogue |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
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| Hit | Length | Start | End | EValue |
| HO780776 | 515 | 115 | 594 | 0 |
| DY974119 | 307 | 257 | 563 | 0 |
| CU615093 | 322 | 336 | 657 | 0 |
| GO877285 | 308 | 244 | 551 | 0 |
| HO780776 | 75 | 585 | 657 | 7e-16 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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