Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000308736 |
Family | GT57 |
Protein Properties | Length: 521 Molecular Weight: 59592.4 Isoelectric Point: 9.7705 |
Chromosome | Chromosome/Scaffold: 020340329 Start: 45912 End: 49112 |
Description | ALG6, ALG8 glycosyltransferase family |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT57 | 46 | 500 | 0 |
LLVRAAVSLHPYSGAGNPPKFGDFEAQRHWMEITINLPINQWYRNSTVNDLGYWGLDYPPLTAYQSYVHGLFLRHFSPESVALFASRGHESYLGKLLMRW TVLSSDALVFFPAVLYFVLVYYAGQNPSRRRSDIAWHITIILLNPCLILIDHGHFQYNCISLGLTVGAIASVLSDKDLVACVLYSLALNHKQMSAYFAPA FFSHLLGKCLRRRYPVLEVLKLGLVVLXTFVVVWWPYVHSTEAFFGVLSRLAPFERGIFEDYVANFWCTTSVLVKWKRLFPTQSLKLISLGATVSTFLPS MIQQIWAPSKPGFLYGLLNSAFSFYLFSFQVHEKSILLPLLPASLLAMEEPFLFTWMTLYALFSMFPLLHRDKLVLPYLALSALFILLNHVPNGRRTTRD TSALRSFVITVSVLCSVVLHVVYLSLHPPARYPFLFEAXIMLVCFSQFVXLTVYT |
Full Sequence |
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Protein Sequence Length: 521 Download |
MDKTSKKKGN FRKGKDEKLI VESDGWWWLI HRGITASFLS IALFSLLVRA AVSLHPYSGA 60 GNPPKFGDFE AQRHWMEITI NLPINQWYRN STVNDLGYWG LDYPPLTAYQ SYVHGLFLRH 120 FSPESVALFA SRGHESYLGK LLMRWTVLSS DALVFFPAVL YFVLVYYAGQ NPSRRRSDIA 180 WHITIILLNP CLILIDHGHF QYNCISLGLT VGAIASVLSD KDLVACVLYS LALNHKQMSA 240 YFAPAFFSHL LGKCLRRRYP VLEVLKLGLV VLXTFVVVWW PYVHSTEAFF GVLSRLAPFE 300 RGIFEDYVAN FWCTTSVLVK WKRLFPTQSL KLISLGATVS TFLPSMIQQI WAPSKPGFLY 360 GLLNSAFSFY LFSFQVHEKS ILLPLLPASL LAMEEPFLFT WMTLYALFSM FPLLHRDKLV 420 LPYLALSALF ILLNHVPNGR RTTRDTSALR SFVITVSVLC SVVLHVVYLS LHPPARYPFL 480 FEAXIMLVCF SQFVXLTVYT NAKQWMLLKH SNLVDKEKKL L |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03155 | Alg6_Alg8 | 7.0e-100 | 48 | 502 | 468 | + ALG6, ALG8 glycosyltransferase family. N-linked (asparagine-linked) glycosylation of proteins is mediated by a highly conserved pathway in eukaryotes, in which a lipid (dolichol phosphate)-linked oligosaccharide is assembled at the endoplasmic reticulum membrane prior to the transfer of the oligosaccharide moiety to the target asparagine residues. This oligosaccharide is composed of Glc(3)Man(9)GlcNAc(2). The addition of the three glucose residues is the final series of steps in the synthesis of the oligosaccharide precursor. Alg6 transfers the first glucose residue, and Alg8 transfers the second one. In the human alg6 gene, a C->T transition, which causes Ala333 to be replaced with Val, has been identified as the cause of a congenital disorder of glycosylation, designated as type Ic OMIM:603147. |
Gene Ontology | |
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GO Term | Description |
GO:0005789 | endoplasmic reticulum membrane |
GO:0016758 | transferase activity, transferring hexosyl groups |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_001145139.1 | 0 | 41 | 520 | 36 | 519 | hypothetical protein LOC100278369 [Zea mays] |
RefSeq | NP_198662.1 | 0 | 6 | 519 | 3 | 531 | ALG6, ALG8 glycosyltransferase family protein [Arabidopsis thaliana] |
RefSeq | XP_002280181.1 | 0 | 1 | 521 | 1 | 516 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002305159.1 | 0 | 49 | 520 | 15 | 490 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002329281.1 | 0 | 49 | 520 | 11 | 485 | predicted protein [Populus trichocarpa] |