Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000309120 |
Family | GT47 |
Protein Properties | Length: 1241 Molecular Weight: 139376 Isoelectric Point: 8.5594 |
Chromosome | Chromosome/Scaffold: 019220296 Start: 446 End: 11847 |
Description | alpha/beta-Hydrolases superfamily protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 509 | 676 | 0 |
RHHMERCIKALCNADPTSGFKIARDVSLPETYVRSERNPLVDLGGKPPSXRKILAFYAGNMHGYLRPILLEYWKDKDPDMKIFGPMPPGVARKLNYIHHM QSSKYCICPKGYEVNSPRVVEAIFYECVPVIISDNFVPPFFEVLDWGAFSVILAEQDIPKLKEXLVSI |
Full Sequence |
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Protein Sequence Length: 1241 Download |
MTLMFQIRRK NLGMGLILIN RPACMDSHHK RKDWKWVAGE DNDCWWDWAV GSPEKRSHGI 60 HXMKELQSCX RKKRRNPSLK XCASLYSDVX VASELSALQV LVPXMEYTFQ FPKLCNIEPR 120 SRRWLFLLGV VSVTYLSIQS LLIPYGIALR SLSPHSEVPA QVXGSVLPVH SSAKSMMVRN 180 PLKVNSLDSI DVSMFGGDIR QGTEPKGNDV SKEIDLMLEE REIDNDFESD INRNVDDDFP 240 SENVVVVNES LALVSIMNRE NVTILHKADE TRHGFHLKKI VLPNSEITRE NASKENSTVT 300 AKRSDGVETA FHSSPLILPA ANLLENRSTS VGSTSLKSGV VASKNGSVVM TRPGKKKMRC 360 ELPPXSITSI SEMNRILVRK RVSSLSPKPR WSSXRDQEIL AAKSQIKHPP VAINDPELYA 420 PLFRNVSMFK RSYELMERTL KIYIYKEGNK PIFHQPILKG LYASEGWFMK LMQGYKRFLV 480 KDPSKAHLFY MPFSSRMLEY ALYAPYETRH HMERCIKALC NADPTSGFKI ARDVSLPETY 540 VRSERNPLVD LGGKPPSXRK ILAFYAGNMH GYLRPILLEY WKDKDPDMKI FGPMPPGVAR 600 KLNYIHHMQS SKYCICPKGY EVNSPRVVEA IFYECVPVII SDNFVPPFFE VLDWGAFSVI 660 LAEQDIPKLK EXLVSIPEEK YLQLQLGVRK VQKHFLWHAK PLKYDLFHMT LHSIWNLLLG 720 FSNRPSLTCQ SSNLLSFLVV SSGFKELMGD VVFENDISEM PVTNVMDGFG NDVIAEDLAR 780 TDADRCSDDL LVNSAGQYLR SLRHGVCNSF FEGYSSSSKS CLSGQNPGIC ERVSEPREDA 840 RTEIVAAKSS YAVVPFIFKG LVLPLHGLQF AWXLAMSCCR SSVAYVRCAH LRICSIASRI 900 QKSLRGSADD IGWLQRTDGM PGVEDGTARF LELLAGIRNF ELSGLFSNHG PLYFVGTKKF 960 FSKMGLACHI AKIHSEASVA HNAWELKQYI EELYWGSGKR VMLLGHSKGG VDAAAALSVY 1020 WGDLKDKVAG LALVQSPYGG TPLASDCLRE GQVADKETRR IMELLICKLI KGDIRALEDL 1080 TYEKRKEFIL NHKLPAEQIP LISFHSEASI APGVLATMTH IAHAELPWLP LPNFGNKESD 1140 EIIQAGRQLP VVIPLSAAMA LTALHLQLRY GEKSDGLVTC RDAEVPGSVV VRPDRKLDHA 1200 WMVYSTKKRN PGEADASEMC EAILTLLVEL GKLKEEAKAM N |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam07819 | PGAP1 | 0.004 | 988 | 1046 | 62 | + PGAP1-like protein. The sequences found in this family are similar to PGAP1. This is an endoplasmic reticulum membrane protein with a catalytic serine containing motif that is conserved in a number of lipases. PGAP1 functions as a GPI inositol-deacylase; this deacylation is important for the efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi body. | ||
pfam03016 | Exostosin | 3.0e-44 | 436 | 676 | 297 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN76867.1 | 0 | 105 | 503 | 1 | 399 | hypothetical protein [Vitis vinifera] |
EMBL | CAN76867.1 | 0 | 105 | 715 | 710 | 1384 | hypothetical protein [Vitis vinifera] |
EMBL | CAN76867.1 | 0 | 504 | 715 | 492 | 703 | hypothetical protein [Vitis vinifera] |
EMBL | CAN76867.1 | 0 | 861 | 1238 | 1538 | 1906 | hypothetical protein [Vitis vinifera] |
RefSeq | XP_002514248.1 | 0 | 105 | 715 | 1 | 666 | catalytic, putative [Ricinus communis] |