Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000312089 |
Family | GH18 |
Protein Properties | Length: 561 Molecular Weight: 63302.9 Isoelectric Point: 4.8501 |
Chromosome | Chromosome/Scaffold: 01939049 Start: 34349 End: 38287 |
Description | |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GH18 | 25 | 192 | 8.5e-21 |
VPIDNEIDFHFILGFAIDADSSGKQQNGIFSPYWQSTLTPQSVAAIKEKNPNVKVMASLSGWSLGDKVLHWYNPTNPKKWVSNAVSSLGSIITTYHLDGI DIDYENFPKRGNSSSFAFCIGELITGLKKKGLISVASIAPFYSTAAPYVQLFDDYADVIDYVNHQFYT |
Full Sequence |
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Protein Sequence Length: 561 Download |
MHDSDGKLMM EYIGATGVPX TFDSVPIDNE IDFHFILGFA IDADSSGKQQ NGIFSPYWQS 60 TLTPQSVAAI KEKNPNVKVM ASLSGWSLGD KVLHWYNPTN PKKWVSNAVS SLGSIITTYH 120 LDGIDIDYEN FPKRGNSSSF AFCIGELITG LKKKGLISVA SIAPFYSTAA PYVQLFDDYA 180 DVIDYVNHQF YTDKVXTPKX YLQAFKIRAA QFGKEKLLPA YEVDGRGIQG DAFFDALTLL 240 QTNGFXINGV MIFSADASLK NNFHYERKSQ AFLLNSTTPI TARARPFARE GIRPLRVXWF 300 ALTSXXLIGN MSRLKLSLQR LVMVMWVYGV IICKNLGDNK QLIVKQFFSD LYELYLEKTG 360 QPIIRKEAKV MENDISLCQE TVEAKVEAKE QVIFLDENLV DEDLRKHDNS EVEAQEIQGM 420 SESKSVMTLE NHESSKLDLN SIVDQTRELG KEEYFDSQLP YFDLIYGINF MIIPPKYTES 480 WASQVEELIF LTRELSTSYQ DRFKTNSRSS SLQVDESDVG QKSDYFTHMH EVDDVIRTQG 540 SRDGVAGDSA TADGRLTALQ L |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd06548 | GH18_chitinase | 4.0e-9 | 36 | 132 | 101 | + The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an eight-stranded alpha/beta barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel. | ||
smart00636 | Glyco_18 | 2.0e-12 | 34 | 192 | 174 | + Glyco_18 domain. | ||
cd00598 | GH18_chitinase-like | 3.0e-15 | 9 | 191 | 191 | + The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods. Chitinases have been identified in viruses, bacteria, fungi, protozoan parasites, insects, and plants. The structure of the GH18 domain is an eight-stranded beta/alpha barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel. The GH18 family includes chitotriosidase, chitobiase, hevamine, zymocin-alpha, narbonin, SI-CLP (stabilin-1 interacting chitinase-like protein), IDGF (imaginal disc growth factor), CFLE (cortical fragment-lytic enzyme) spore hydrolase, the type III and type V plant chitinases, the endo-beta-N-acetylglucosaminidases, and the chitolectins. The GH85 (glycosyl hydrolase, family 85) ENGases (endo-beta-N-acetylglucosaminidases) are closely related to the GH18 chitinases and are included in this alignment model. | ||
pfam00704 | Glyco_hydro_18 | 8.0e-17 | 34 | 191 | 165 | + Glycosyl hydrolases family 18. | ||
cd06544 | GH18_narbonin | 2.0e-99 | 8 | 258 | 257 | + Narbonin is a plant 2S protein from the globulin fraction of narbon bean (Vicia narbonensis L.) cotyledons with unknown function. Narbonin has a glycosyl hydrolase family 18 (GH18) domain without the conserved catalytic residues and with no known enzymatic activity. Narbonin amounts to up to 3% of the total seed globulins of mature seeds and was thought to be a storage protein but was found to degrade too slowly during germination. This family also includes the VfNOD32 nodulin from Vicia faba. |
Gene Ontology | |
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GO Term | Description |
GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
GO:0005975 | carbohydrate metabolic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAE98134.1 | 0 | 5 | 273 | 151 | 421 | chitinase A [Pteris ryukyuensis] |
EMBL | CAN65355.1 | 0 | 4 | 277 | 138 | 409 | hypothetical protein [Vitis vinifera] |
RefSeq | XP_002274616.1 | 0 | 1 | 277 | 59 | 333 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002328469.1 | 0 | 10 | 278 | 1 | 267 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002517257.1 | 0 | 9 | 278 | 1 | 268 | Chitinase 1 precursor, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3sim_B | 0 | 8 | 275 | 2 | 275 | A Chain A, Crystallographic Structure Analysis Of Family 18 Chitinase From Crocus Vernus |
PDB | 3sim_A | 0 | 8 | 275 | 2 | 275 | A Chain A, Crystallographic Structure Analysis Of Family 18 Chitinase From Crocus Vernus |
PDB | 1nar_A | 4e-26 | 8 | 259 | 4 | 267 | A Chain A, Crystal Structure Of Narbonin Refined At 1.8 Angstroms Resolution |
PDB | 3qok_A | 0.005 | 54 | 135 | 87 | 161 | A Chain A, Crystal Structure Of Putative Chitinase Ii From Klebsiella Pneumoniae |
PDB | 1h0i_B | 0.006 | 67 | 170 | 78 | 184 | A Chain A, Crystal Structure Of Putative Chitinase Ii From Klebsiella Pneumoniae |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
DY831286 | 271 | 4 | 270 | 0 |
JG186119 | 195 | 4 | 195 | 0 |
CO165323 | 281 | 4 | 273 | 0 |
HO825986 | 276 | 5 | 273 | 0 |
DY618350 | 274 | 8 | 273 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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