| Basic Information | |
|---|---|
| Species | Malus domestica |
| Cazyme ID | MDP0000316328 |
| Family | GH47 |
| Protein Properties | Length: 277 Molecular Weight: 31455.8 Isoelectric Point: 8.9396 |
| Chromosome | Chromosome/Scaffold: 0334267 Start: 15974 End: 22739 |
| Description | alpha-mannosidase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH47 | 114 | 263 | 7.29936e-42 |
| RGKSILADAGSEQLEFIALSQRTKDPKYQQKVEYVIKELHKIFPADGLLPIYINPLTGETSYSKITFGAMGDSFYEYLLKAWIQGNKTEAVKNYREMWET SMKGLKSLIRRTTPSSFAYICEKTGSSLYDKMDELACFAPGMLALGSSGY | |||
| Full Sequence |
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| Protein Sequence Length: 277 Download |
| MVGRRSLGQY SSRSNTLKEL QIWCPKLREI PLQPQLDHPG WPKEKXCGQQ LGFGNHGGLR 60 KHYQLVYVVV HPLLLKYRIE LVYPLRPALX FHQIEAKMPA SAEYGLGVNY FSLRGKSILA 120 DAGSEQLEFI ALSQRTKDPK YQQKVEYVIK ELHKIFPADG LLPIYINPLT GETSYSKITF 180 GAMGDSFYEY LLKAWIQGNK TEAVKNYREM WETSMKGLKS LIRRTTPSSF AYICEKTGSS 240 LYDKMDELAC FAPGMLALGS SGYVPDEAEK FLSLAEE 300 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PTZ00470 | PTZ00470 | 8.0e-44 | 114 | 277 | 168 | + glycoside hydrolase family 47 protein; Provisional | ||
| pfam01532 | Glyco_hydro_47 | 1.0e-50 | 114 | 277 | 171 | + Glycosyl hydrolase family 47. Members of this family are alpha-mannosidases that catalyze the hydrolysis of the terminal 1,2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2). | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity |
| GO:0005509 | calcium ion binding |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI18472.1 | 0 | 115 | 277 | 247 | 409 | unnamed protein product [Vitis vinifera] |
| EMBL | CBI18482.1 | 0 | 115 | 277 | 22 | 184 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002263484.1 | 0 | 104 | 277 | 126 | 299 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002325257.1 | 0 | 105 | 277 | 234 | 406 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002519409.1 | 0 | 115 | 277 | 234 | 396 | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1nxc_A | 5e-30 | 57 | 277 | 112 | 328 | A Chain A, Structure Of Mouse Golgi Alpha-1,2-Mannosidase Ia Reveals The Molecular Basis For Substrate Specificity Among Class I Enzymes (Family 47 Glycosidases) |
| PDB | 1fmi_A | 7e-25 | 117 | 259 | 154 | 297 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo3_A | 8e-25 | 117 | 259 | 154 | 297 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo2_A | 8e-25 | 117 | 259 | 154 | 297 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase In Complex With 1-Deoxymannojirimycin |
| PDB | 1x9d_A | 3e-24 | 117 | 259 | 232 | 375 | A Chain A, Crystal Structure Of Human Class I Alpha-1,2-Mannosidase In Complex With Thio-Disaccharide Substrate Analogue |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| BU044884 | 160 | 118 | 277 | 0 |
| DV147459 | 163 | 115 | 277 | 0 |
| EY159230 | 161 | 115 | 275 | 0 |
| GW453914 | 163 | 115 | 277 | 0 |
| GW436615 | 163 | 115 | 277 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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