Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000316785 |
Family | GT47 |
Protein Properties | Length: 591 Molecular Weight: 66322.6 Isoelectric Point: 8.6313 |
Chromosome | Chromosome/Scaffold: 02937243 Start: 27740 End: 32929 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 44 | 339 | 0 |
RLKVFVYELPSKYNKKILQKDPRCLNHMFAAEIFMHRFLLSSPVRTLNPEEADWFYTPVYTTCDLTPNGLPLPFKSPRMMRSAIQLISSNWPYWNRTEGA DHFFVVPHDFGACFHYLEEKAIERGILPMLQRATLVQTFGQKNHVCLKEGSITVPPYAPPQKMQTHLIPEKTPRSIFVYFRGLFYDVGNDPEGGYYARGA RAAVWENFKDNPLFDISTEHPTTYYEDMQRAVFCLCPLGWAPWSPRLVEAVIFGCIPVIIADDIVLPFADAIPWEEIGVFVDEKDVPNLDTILTSI |
Full Sequence |
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Protein Sequence Length: 591 Download |
MVGVDLALII VNLHIVLNFD LTIISLVSET SSAGDVLDDD PVGRLKVFVY ELPSKYNKKI 60 LQKDPRCLNH MFAAEIFMHR FLLSSPVRTL NPEEADWFYT PVYTTCDLTP NGLPLPFKSP 120 RMMRSAIQLI SSNWPYWNRT EGADHFFVVP HDFGACFHYL EEKAIERGIL PMLQRATLVQ 180 TFGQKNHVCL KEGSITVPPY APPQKMQTHL IPEKTPRSIF VYFRGLFYDV GNDPEGGYYA 240 RGARAAVWEN FKDNPLFDIS TEHPTTYYED MQRAVFCLCP LGWAPWSPRL VEAVIFGCIP 300 VIIADDIVLP FADAIPWEEI GVFVDEKDVP NLDTILTSIP PELILRKQRL LANPSMKQAM 360 LFPQPAESGD AFHQVLNGLA RKLPHSPDVF LKPGEKILNW TAGPAPTTRS HLAPPSPLAA 420 PKGNAGLRQP PDRFALKSSF FSSSHDLLLL SPKHRPRASS AAPKFSMRVA SKGAYICRDC 480 GYHILHLLFL TRRYSNYSNL RERDSNLGFS LFFFNLDGHG DAAAVCGAPK RRFRPYQPPV 540 TKDANSKDVR KQRKAQLQRE ETIGKALPIA VAVGAVALVG LYFYINVGFQ G 600 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-79 | 44 | 339 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAM64940.1 | 0 | 30 | 405 | 34 | 409 | unknown [Arabidopsis thaliana] |
RefSeq | NP_568941.1 | 0 | 30 | 405 | 34 | 409 | GUT1; catalytic/ glucuronoxylan glucuronosyltransferase [Arabidopsis thaliana] |
RefSeq | XP_002284685.1 | 0 | 30 | 405 | 35 | 410 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002318180.1 | 0 | 30 | 405 | 36 | 411 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002511079.1 | 0 | 30 | 405 | 36 | 411 | catalytic, putative [Ricinus communis] |