y
Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000317931 |
Family | GT47 |
Protein Properties | Length: 515 Molecular Weight: 58843.1 Isoelectric Point: 6.9564 |
Chromosome | Chromosome/Scaffold: 02973515 Start: 13467 End: 15083 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 61 | 406 | 0 |
CFGRYVYMHDDLPEKFNSDLVRNCRFLTRGTDKPNLCMYFENYGFGPEIQNSEGVLSNGSWFSTNQFLLEFIFHNKMKRYKCLTNISSQASAVYVPFYAG LDASLHLWDSNLTVRDASAKELVSWLARKPEWGKLWGRDHFLVAGRISWDFRRQTDEVSDWGSKLRWLPESMNMTMLSVEGSSWNNDFAIPYPTNFHPAE EVDLVQWQNRMRKLDRPYLFTFAGAPRPDQQSSIRGKIIDQCVASSRCKLIDCSLGGNMDCDNPSSVMRVFQSSVYCLQPGGDSYTRRSTFDSILAGCIP VFFHPGAAYSQYLWHLPKNHSSYSVYIPVRVADDMPGSIEEILLGI |
Full Sequence |
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Protein Sequence Length: 515 Download |
MEKLPTVKCS QELWFALLIS SALCIIFLSF DYSTFSGLNL LPNKKVDPIG VLNHAITDSS 60 CFGRYVYMHD DLPEKFNSDL VRNCRFLTRG TDKPNLCMYF ENYGFGPEIQ NSEGVLSNGS 120 WFSTNQFLLE FIFHNKMKRY KCLTNISSQA SAVYVPFYAG LDASLHLWDS NLTVRDASAK 180 ELVSWLARKP EWGKLWGRDH FLVAGRISWD FRRQTDEVSD WGSKLRWLPE SMNMTMLSVE 240 GSSWNNDFAI PYPTNFHPAE EVDLVQWQNR MRKLDRPYLF TFAGAPRPDQ QSSIRGKIID 300 QCVASSRCKL IDCSLGGNMD CDNPSSVMRV FQSSVYCLQP GGDSYTRRST FDSILAGCIP 360 VFFHPGAAYS QYLWHLPKNH SSYSVYIPVR VADDMPGSIE EILLGISKDK ELSMREEVIR 420 LIPNLSYSDP RSRLETEDAF DLAIKGILER IEDVRKVIRE GNDPSIGFAD EDSYKMRWKR 480 RCRPTMADRT SKDSKLDETV PVLGFQVVTA AAKRL 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-64 | 103 | 406 | 318 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_193135.2 | 0 | 13 | 475 | 31 | 508 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002300146.1 | 0 | 1 | 475 | 7 | 509 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002321098.1 | 0 | 60 | 477 | 49 | 464 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002518609.1 | 0 | 11 | 480 | 9 | 491 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
RefSeq | XP_002532518.1 | 0 | 1 | 475 | 1 | 518 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |