| Basic Information | |
|---|---|
| Species | Malus domestica |
| Cazyme ID | MDP0000319902 |
| Family | CE11 |
| Protein Properties | Length: 248 Molecular Weight: 27595.2 Isoelectric Point: 6.2459 |
| Chromosome | Chromosome/Scaffold: 02002449 Start: 218 End: 1839 |
| Description | UDP-3-O-acyl N-acetylglycosamine deacetylase family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| CE11 | 25 | 247 | 0 |
| QQTLAGCIERKGKSLHSGKVSAVKLWPDHAGKGRYFVCRSNAIRASVEFAEESPLCTTLCKDGVKIRTVEHLLSALEAMEVDNCRIEVKNSDPEDIDVEV PIFDGSAREWVEAIKQVGLKEATDEHGNCCEKMAAHMNEPVHVWRNNSFVAAFPSPEIRITYGIDFPQVDAIGCQWFSVTSLDNSFYSKQIALSRTFCIY EEVERMREAGLIKGGGLENAIVC | |||
| Full Sequence |
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| Protein Sequence Length: 248 Download |
| MTLSSAFNAF KSSKSIFWKS TGRLQQTLAG CIERKGKSLH SGKVSAVKLW PDHAGKGRYF 60 VCRSNAIRAS VEFAEESPLC TTLCKDGVKI RTVEHLLSAL EAMEVDNCRI EVKNSDPEDI 120 DVEVPIFDGS AREWVEAIKQ VGLKEATDEH GNCCEKMAAH MNEPVHVWRN NSFVAAFPSP 180 EIRITYGIDF PQVDAIGCQW FSVTSLDNSF YSKQIALSRT FCIYEEVERM REAGLIKGGG 240 LENAIVCX |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PRK13188 | PRK13188 | 5.0e-46 | 25 | 246 | 229 | + bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Reviewed | ||
| TIGR00325 | lpxC | 1.0e-48 | 25 | 247 | 228 | + UDP-3-0-acyl N-acetylglucosamine deacetylase. UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc deacetylase from E. coli , LpxC, was previously designated EnvA. This enzyme is involved in lipid-A precursor biosynthesis. It is essential for cell viability [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]. | ||
| COG0774 | LpxC | 7.0e-58 | 23 | 247 | 232 | + UDP-3-O-acyl-N-acetylglucosamine deacetylase [Cell envelope biogenesis, outer membrane] | ||
| pfam03331 | LpxC | 2.0e-59 | 25 | 247 | 227 | + UDP-3-O-acyl N-acetylglycosamine deacetylase. The enzymes in this family catalyze the second step in the biosynthetic pathway for lipid A. | ||
| PRK13186 | lpxC | 2.0e-71 | 25 | 247 | 228 | + UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008759 | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity |
| GO:0009245 | lipid A biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI26831.1 | 0 | 1 | 247 | 1 | 247 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_001117351.1 | 0 | 7 | 246 | 21 | 260 | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Arabidopsis thaliana] |
| RefSeq | NP_173874.2 | 0 | 7 | 247 | 21 | 261 | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Arabidopsis thaliana] |
| RefSeq | NP_173884.5 | 0 | 7 | 247 | 64 | 304 | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Arabidopsis thaliana] |
| RefSeq | XP_002281269.1 | 0 | 1 | 247 | 1 | 247 | PREDICTED: hypothetical protein [Vitis vinifera] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1xxe_A | 3e-24 | 24 | 247 | 3 | 206 | A Chain A, Rdc Refined Solution Structure Of The AalpxcTU-514 Complex |
| PDB | 4j3d_B | 4e-24 | 25 | 247 | 4 | 217 | A Chain A, Pseudomonas Aeruginosa Lpxc In Complex With A Hydroxamate Inhibitor |
| PDB | 4j3d_A | 4e-24 | 25 | 247 | 4 | 217 | A Chain A, Pseudomonas Aeruginosa Lpxc In Complex With A Hydroxamate Inhibitor |
| PDB | 3p76_A | 2e-23 | 24 | 247 | 3 | 206 | A Chain A, Pseudomonas Aeruginosa Lpxc In Complex With A Hydroxamate Inhibitor |
| PDB | 2o3z_B | 2e-23 | 24 | 247 | 3 | 206 | A Chain A, Pseudomonas Aeruginosa Lpxc In Complex With A Hydroxamate Inhibitor |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| FC462005 | 227 | 16 | 242 | 0 |
| FG933373 | 224 | 16 | 239 | 0 |
| GW831538 | 197 | 16 | 212 | 0 |
| FG425892 | 216 | 16 | 231 | 0 |
| FE708350 | 219 | 21 | 239 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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