| Basic Information | |
|---|---|
| Species | Malus domestica |
| Cazyme ID | MDP0000598998 |
| Family | GH18 |
| Protein Properties | Length: 652 Molecular Weight: 73275.5 Isoelectric Point: 8.8874 |
| Chromosome | Chromosome/Scaffold: 00191590 Start: 6507 End: 10337 |
| Description | Glycosyl hydrolase family protein with chitinase insertion domain |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH18 | 28 | 364 | 0 |
| AGYWYAGSESPIPEINSALFTHLICGFADVNXSTYQLSIPSAHVQYFSSFTDIVKRKNPSTITVLSIWNGQAETGRAILGENANFSVLSSMLENPSNRRS FIESSIKMARRYGFRGIDLFWLWPSEASDMNNMGKLLDEWRAAVTXESRNSSQSQLLLTMAVRYLPAFESLSYPIDSMKRNLDWAHVVAYDYHLPSKENV TGAHAALYNPLSHVNTDYGIRQWLNYSFPAGKLVLGLPYHGYAWTLXKPEENNGIGAPASGTAVTKDGSMSYKYIKGYTRSYQAPIVYNATYVVNYCIXG SSWVGFDDVEAIRAKIAYAKEKKLLGXNVFLVTNDDD | |||
| Full Sequence |
|---|
| Protein Sequence Length: 652 Download |
| MEFRNLPYLI IPLIFFVSCS SAQSWIRAGY WYAGSESPIP EINSALFTHL ICGFADVNXS 60 TYQLSIPSAH VQYFSSFTDI VKRKNPSTIT VLSIWNGQAE TGRAILGENA NFSVLSSMLE 120 NPSNRRSFIE SSIKMARRYG FRGIDLFWLW PSEASDMNNM GKLLDEWRAA VTXESRNSSQ 180 SQLLLTMAVR YLPAFESLSY PIDSMKRNLD WAHVVAYDYH LPSKENVTGA HAALYNPLSH 240 VNTDYGIRQW LNYSFPAGKL VLGLPYHGYA WTLXKPEENN GIGAPASGTA VTKDGSMSYK 300 YIKGYTRSYQ APIVYNATYV VNYCIXGSSW VGFDDVEAIR AKIAYAKEKK LLGXNVFLVT 360 NDDDNWALSR AGRIILGNSR ASDPSNPQVF SFSEIKAATN KFSSENKLGE GGFGPVYKGK 420 LRTGQEIAVK RLSKTSTQGL XEFGNEVTLT ANLQHVNLVR VLGFCSEKEE KMLIYEYMPN 480 RSLDFXLFAG HWYAGSKSHI PEINSALFTH LTCAFVNXNX STYRLSIPSA HEQYFXSFTD 540 IVKSKNPSIK XLLFXWNKEA AASQLILGQR AHFSALSKML XXXSNRKSFI ESSIELARCY 600 FQGIDLLWPW LNTALDMINM EKLLDEWRAA VTSEARNTGL SXLKLTMAFL F* 660 |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| smart00636 | Glyco_18 | 6.0e-12 | 495 | 648 | 160 | + Glyco_18 domain. |
| cd02879 | GH18_plant_chitinase_class_V | 1.0e-45 | 489 | 651 | 165 | + The class V plant chitinases have a glycosyl hydrolase family 18 (GH18) domain, but lack the chitin-binding domain present in other GH18 enzymes. The GH18 domain of the class V chitinases has endochitinase activity in some cases and no catalytic activity in others. Included in this family is a lectin found in black locust (Robinia pseudoacacia) bark, which binds chitin but lacks chitinase activity. Also included is a chitinase-related receptor-like kinase (CHRK1) from tobacco (Nicotiana tabacum), with an N-terminal GH18 domain and a C-terminal kinase domain, which is thought to be part of a plant signaling pathway. The GH18 domain of CHRK1 is expressed extracellularly where it binds chitin but lacks chitinase activity. |
| pfam00704 | Glyco_hydro_18 | 3.0e-65 | 28 | 362 | 344 | + Glycosyl hydrolases family 18. |
| smart00636 | Glyco_18 | 4.0e-71 | 28 | 353 | 345 | + Glyco_18 domain. |
| cd02879 | GH18_plant_chitinase_class_V | 5.0e-130 | 23 | 368 | 351 | + The class V plant chitinases have a glycosyl hydrolase family 18 (GH18) domain, but lack the chitin-binding domain present in other GH18 enzymes. The GH18 domain of the class V chitinases has endochitinase activity in some cases and no catalytic activity in others. Included in this family is a lectin found in black locust (Robinia pseudoacacia) bark, which binds chitin but lacks chitinase activity. Also included is a chitinase-related receptor-like kinase (CHRK1) from tobacco (Nicotiana tabacum), with an N-terminal GH18 domain and a C-terminal kinase domain, which is thought to be part of a plant signaling pathway. The GH18 domain of CHRK1 is expressed extracellularly where it binds chitin but lacks chitinase activity. |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
| GO:0004672 | protein kinase activity |
| GO:0005524 | ATP binding |
| GO:0005975 | carbohydrate metabolic process |
| GO:0006468 | protein phosphorylation |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_002263709.1 | 0 | 20 | 488 | 20 | 531 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002263709.1 | 3.9937e-43 | 489 | 648 | 28 | 188 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002263792.1 | 0 | 9 | 488 | 8 | 519 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002270006.1 | 0 | 20 | 488 | 20 | 531 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002270006.1 | 2.00386e-43 | 489 | 648 | 28 | 188 | PREDICTED: hypothetical protein [Vitis vinifera] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3aqu_D | 0 | 23 | 371 | 2 | 338 | A Chain A, Crystal Structure Of A Class V Chitinase From Arabidopsis Thaliana |
| PDB | 3aqu_D | 5e-28 | 489 | 651 | 7 | 159 | A Chain A, Crystal Structure Of A Class V Chitinase From Arabidopsis Thaliana |
| PDB | 3aqu_C | 0 | 23 | 371 | 2 | 338 | A Chain A, Crystal Structure Of A Class V Chitinase From Arabidopsis Thaliana |
| PDB | 3aqu_C | 5e-28 | 489 | 651 | 7 | 159 | A Chain A, Crystal Structure Of A Class V Chitinase From Arabidopsis Thaliana |
| PDB | 3aqu_B | 0 | 23 | 371 | 2 | 338 | A Chain A, Crystal Structure Of A Class V Chitinase From Arabidopsis Thaliana |
